CA1148172A - 1-(acylaminoaryloxy-)2-hydroxy-3-alkinylaminopropanes and processes for their production - Google Patents

1-(acylaminoaryloxy-)2-hydroxy-3-alkinylaminopropanes and processes for their production

Info

Publication number
CA1148172A
CA1148172A CA000372484A CA372484A CA1148172A CA 1148172 A CA1148172 A CA 1148172A CA 000372484 A CA000372484 A CA 000372484A CA 372484 A CA372484 A CA 372484A CA 1148172 A CA1148172 A CA 1148172A
Authority
CA
Canada
Prior art keywords
formula
group
acid addition
compound
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000372484A
Other languages
English (en)
French (fr)
Inventor
Herbert Koppe
Werner Kummer
Helmut Stahle
Gojko Muacevic
Werner Traunecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Application granted granted Critical
Publication of CA1148172A publication Critical patent/CA1148172A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Pyrrole Compounds (AREA)
CA000372484A 1980-03-08 1981-03-06 1-(acylaminoaryloxy-)2-hydroxy-3-alkinylaminopropanes and processes for their production Expired CA1148172A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3009036.9 1980-03-08
DE19803009036 DE3009036A1 (de) 1980-03-08 1980-03-08 Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CA1148172A true CA1148172A (en) 1983-06-14

Family

ID=6096683

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000372484A Expired CA1148172A (en) 1980-03-08 1981-03-06 1-(acylaminoaryloxy-)2-hydroxy-3-alkinylaminopropanes and processes for their production

Country Status (18)

Country Link
US (1) US4344964A (index.php)
EP (1) EP0035734B1 (index.php)
JP (1) JPS56139447A (index.php)
AT (1) ATE4704T1 (index.php)
AU (1) AU541550B2 (index.php)
CA (1) CA1148172A (index.php)
DE (2) DE3009036A1 (index.php)
DK (1) DK102681A (index.php)
ES (3) ES8205395A1 (index.php)
FI (1) FI73665C (index.php)
GB (1) GB2071097B (index.php)
GR (1) GR78243B (index.php)
IE (1) IE52016B1 (index.php)
IL (1) IL62310A (index.php)
NO (1) NO150960C (index.php)
NZ (1) NZ196447A (index.php)
PT (1) PT72621B (index.php)
ZA (1) ZA811501B (index.php)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3009047A1 (de) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung
DE3133719A1 (de) * 1981-08-26 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-aryloxy-3-alkinylamino-2-propanole und verfahren zu ihrer herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH546224A (en) * 1969-08-08 1974-02-28 Boehringer Sohn Ingelheim 1-(2-nitrilophenoxy)-2-hydroxy-3-ethylamino - propane
CH546227A (en) * 1969-08-08 1974-02-28 Boehringer Sohn Ingelheim 1-(2-nitrilophenoxy)-2-hydroxy-3-ethylamino - propane
DE2403809C2 (de) * 1974-01-26 1986-02-27 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropane und Verfahren zu ihrer Herstellung und pharmazeutische Präparate
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen

Also Published As

Publication number Publication date
FI810713L (fi) 1981-09-09
DE3160912D1 (en) 1983-10-27
NO150960B (no) 1984-10-08
PT72621A (de) 1981-04-01
DE3009036A1 (de) 1981-09-24
ATE4704T1 (de) 1983-10-15
NO810763L (no) 1981-09-09
NZ196447A (en) 1984-05-31
ES500153A0 (es) 1982-06-01
ES509452A0 (es) 1983-01-16
DK102681A (da) 1981-09-09
IE52016B1 (en) 1987-05-27
AU541550B2 (en) 1985-01-10
EP0035734B1 (de) 1983-09-21
EP0035734A1 (de) 1981-09-16
ES8205395A1 (es) 1982-06-01
FI73665B (fi) 1987-07-31
GR78243B (index.php) 1984-09-26
ES8302637A1 (es) 1983-01-16
NO150960C (no) 1985-01-16
ZA811501B (en) 1982-11-24
IL62310A0 (en) 1981-05-20
ES8302636A1 (es) 1983-01-16
AU6815681A (en) 1981-09-17
JPS56139447A (en) 1981-10-30
GB2071097A (en) 1981-09-16
GB2071097B (en) 1983-07-06
IE810487L (en) 1981-09-08
IL62310A (en) 1984-12-31
PT72621B (de) 1982-11-15
ES509451A0 (es) 1983-01-16
FI73665C (fi) 1987-11-09
US4344964A (en) 1982-08-17

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Legal Events

Date Code Title Description
MKEX Expiry