CA1144165A - N-pyrrolyl pyridazineamines - Google Patents

N-pyrrolyl pyridazineamines

Info

Publication number
CA1144165A
CA1144165A CA000336843A CA336843A CA1144165A CA 1144165 A CA1144165 A CA 1144165A CA 000336843 A CA000336843 A CA 000336843A CA 336843 A CA336843 A CA 336843A CA 1144165 A CA1144165 A CA 1144165A
Authority
CA
Canada
Prior art keywords
lower alkyl
hydrogen
phenyl
represent
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000336843A
Other languages
English (en)
French (fr)
Inventor
Ambrogio Campi
Elvio Bellasio
Nunzio Di Mola
Emiliana Baldoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of CA1144165A publication Critical patent/CA1144165A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000336843A 1978-10-02 1979-10-02 N-pyrrolyl pyridazineamines Expired CA1144165A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB38898/78 1978-10-02
GB7838898 1978-10-02

Publications (1)

Publication Number Publication Date
CA1144165A true CA1144165A (en) 1983-04-05

Family

ID=10500040

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000336843A Expired CA1144165A (en) 1978-10-02 1979-10-02 N-pyrrolyl pyridazineamines

Country Status (15)

Country Link
EP (1) EP0009655B1 (enExample)
JP (1) JPS5569577A (enExample)
AT (1) ATE3294T1 (enExample)
AU (1) AU529482B2 (enExample)
CA (1) CA1144165A (enExample)
DE (1) DE2965377D1 (enExample)
DK (1) DK151803C (enExample)
ES (1) ES484616A1 (enExample)
FI (1) FI65998C (enExample)
GR (1) GR69856B (enExample)
IE (1) IE49017B1 (enExample)
IL (1) IL58256A (enExample)
NO (1) NO151620C (enExample)
YU (1) YU41886B (enExample)
ZA (1) ZA794923B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
US5254622A (en) * 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
JP4831577B2 (ja) * 2003-07-30 2011-12-07 ゼノン・ファーマシューティカルズ・インコーポレイテッド ピリダジン誘導体および治療剤としての用途
AU2005286846A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
WO2006101521A2 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
US7951805B2 (en) 2004-09-20 2011-05-31 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
AU2005286647A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
AR051026A1 (es) 2004-09-20 2006-12-13 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
EP2316458A1 (en) 2004-09-20 2011-05-04 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
JP2009513563A (ja) 2005-06-03 2009-04-02 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトのステアロイル−ＣｏＡデサチュラーゼ阻害剤としてのアミノチアゾール誘導体
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168334A (en) * 1967-01-25 1969-10-22 Lepetit Spa New Pharmacologically Active Pyridazines
GB1378102A (en) * 1972-03-14 1974-12-18 Lepetit Spa Antihypertensive compositions
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives
AU477837B2 (en) * 1973-05-30 1974-12-05 I. S. F. Sp. A New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.

Also Published As

Publication number Publication date
NO793151L (no) 1980-04-08
NO151620B (no) 1985-01-28
GR69856B (enExample) 1982-07-19
ATE3294T1 (de) 1983-05-15
JPS5569577A (en) 1980-05-26
IE49017B1 (en) 1985-07-10
IE791866L (en) 1980-04-02
ZA794923B (en) 1980-09-24
ES484616A1 (es) 1980-05-16
EP0009655B1 (en) 1983-05-11
DK151803C (da) 1988-06-13
DK151803B (da) 1988-01-04
DK400679A (da) 1980-04-03
YU237479A (en) 1983-02-28
FI65998B (fi) 1984-04-30
JPH0321553B2 (enExample) 1991-03-22
DE2965377D1 (en) 1983-06-16
IL58256A (en) 1984-02-29
AU5086679A (en) 1980-04-17
YU41886B (en) 1988-02-29
NO151620C (no) 1985-05-08
IL58256A0 (en) 1979-12-30
AU529482B2 (en) 1983-06-09
FI792832A7 (fi) 1980-04-03
FI65998C (fi) 1984-08-10
EP0009655A1 (en) 1980-04-16

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Legal Events

Date Code Title Description
MKEX Expiry