NO793151L - Nye pyrrolyl-3-pyridazinaminer, fremgangsmaate til deres fremstilling og deres anvendelse som antihypertensive midler - Google Patents

Nye pyrrolyl-3-pyridazinaminer, fremgangsmaate til deres fremstilling og deres anvendelse som antihypertensive midler

Info

Publication number
NO793151L
NO793151L NO793151A NO793151A NO793151L NO 793151 L NO793151 L NO 793151L NO 793151 A NO793151 A NO 793151A NO 793151 A NO793151 A NO 793151A NO 793151 L NO793151 L NO 793151L
Authority
NO
Norway
Prior art keywords
formula
lower alkyl
hydrogen
new
pyrrol
Prior art date
Application number
NO793151A
Other languages
English (en)
Other versions
NO151620C (no
NO151620B (no
Inventor
Elvio Bellasio
Nunzio Di Mola
Ambrogio Campi
Emiliana Baldoli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of NO793151L publication Critical patent/NO793151L/no
Publication of NO151620B publication Critical patent/NO151620B/no
Publication of NO151620C publication Critical patent/NO151620C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
NO793151A 1978-10-02 1979-10-01 Analogifremgangsmaate for fremstilling av terapeutisk virksomme, nye pyrrolyl-3-pyridazinaminer NO151620C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7838898 1978-10-02

Publications (3)

Publication Number Publication Date
NO793151L true NO793151L (no) 1980-04-08
NO151620B NO151620B (no) 1985-01-28
NO151620C NO151620C (no) 1985-05-08

Family

ID=10500040

Family Applications (1)

Application Number Title Priority Date Filing Date
NO793151A NO151620C (no) 1978-10-02 1979-10-01 Analogifremgangsmaate for fremstilling av terapeutisk virksomme, nye pyrrolyl-3-pyridazinaminer

Country Status (15)

Country Link
EP (1) EP0009655B1 (no)
JP (1) JPS5569577A (no)
AT (1) ATE3294T1 (no)
AU (1) AU529482B2 (no)
CA (1) CA1144165A (no)
DE (1) DE2965377D1 (no)
DK (1) DK151803C (no)
ES (1) ES484616A1 (no)
FI (1) FI65998C (no)
GR (1) GR69856B (no)
IE (1) IE49017B1 (no)
IL (1) IL58256A (no)
NO (1) NO151620C (no)
YU (1) YU41886B (no)
ZA (1) ZA794923B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
US5254622A (en) * 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
KR20060037410A (ko) * 2003-07-30 2006-05-03 제논 파마슈티칼스 인크. 피리다진 유도체 및 그의 치료제로서의 용도
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
CA2580787A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
US7592343B2 (en) 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
EP1799668A1 (en) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0611187A2 (pt) 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168334A (en) * 1967-01-25 1969-10-22 Lepetit Spa New Pharmacologically Active Pyridazines
GB1378102A (en) * 1972-03-14 1974-12-18 Lepetit Spa Antihypertensive compositions
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives
AU477837B2 (en) * 1973-05-30 1974-12-05 I. S. F. Sp. A New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.

Also Published As

Publication number Publication date
AU529482B2 (en) 1983-06-09
DE2965377D1 (en) 1983-06-16
CA1144165A (en) 1983-04-05
DK151803C (da) 1988-06-13
JPH0321553B2 (no) 1991-03-22
ES484616A1 (es) 1980-05-16
IE791866L (en) 1980-04-02
DK151803B (da) 1988-01-04
IE49017B1 (en) 1985-07-10
JPS5569577A (en) 1980-05-26
YU237479A (en) 1983-02-28
ZA794923B (en) 1980-09-24
FI65998C (fi) 1984-08-10
NO151620C (no) 1985-05-08
EP0009655A1 (en) 1980-04-16
DK400679A (da) 1980-04-03
FI65998B (fi) 1984-04-30
YU41886B (en) 1988-02-29
FI792832A (fi) 1980-04-03
AU5086679A (en) 1980-04-17
ATE3294T1 (de) 1983-05-15
GR69856B (no) 1982-07-19
IL58256A (en) 1984-02-29
EP0009655B1 (en) 1983-05-11
IL58256A0 (en) 1979-12-30
NO151620B (no) 1985-01-28

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