GB1378102A - Antihypertensive compositions - Google Patents

Antihypertensive compositions

Info

Publication number
GB1378102A
GB1378102A GB320873A GB320873A GB1378102A GB 1378102 A GB1378102 A GB 1378102A GB 320873 A GB320873 A GB 320873A GB 320873 A GB320873 A GB 320873A GB 1378102 A GB1378102 A GB 1378102A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compositions
alkenyl
hydroxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB320873A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of GB1378102A publication Critical patent/GB1378102A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1378102 Antihypertensive compositions GRUPPO LEPETIT SpA 22 Jan 1973 [14 March 1972] 3208/73 Heading A5B Antihypertensive compositions comprise a compound of the general formula wherein R and R 1 are each halogen atoms or C 1-8 alkyl groups, in association with a compound of the general formula: wherein X is H or Cl, R, is H, C 1-8 alkyl, alkenyl or hydroxy-C 1-4 alkyl, R 3 is C,-alkyl, C 2-8 alkenyl, hydroxy-C 1-4 alkyl or phenyl, or R 2 and R 3 together with the nitrogen atom form a heterocyclic ring of 5-7 atoms, R 4 is H 2 or a group =CR 5 R 6 wherein R 5 is H or C 1-8 alkyl and R 6 is C 1-8 alkyl, carboxy or phenyl. The compositions may be in conventional forms for oral and parenteral administration comprising conventional diluents and excipients.
GB320873A 1972-03-14 1973-01-22 Antihypertensive compositions Expired GB1378102A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2179872 1972-03-14

Publications (1)

Publication Number Publication Date
GB1378102A true GB1378102A (en) 1974-12-18

Family

ID=11186980

Family Applications (1)

Application Number Title Priority Date Filing Date
GB320873A Expired GB1378102A (en) 1972-03-14 1973-01-22 Antihypertensive compositions

Country Status (12)

Country Link
JP (1) JPS4899314A (en)
AU (1) AU473956B2 (en)
BE (1) BE796759A (en)
CA (1) CA1018458A (en)
DE (1) DE2308240C3 (en)
FR (1) FR2181820B1 (en)
GB (1) GB1378102A (en)
IE (1) IE37171B1 (en)
IL (1) IL41405A (en)
NL (1) NL149704B (en)
PH (1) PH10526A (en)
ZA (1) ZA73478B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE3294T1 (en) * 1978-10-02 1983-05-15 Gruppo Lepetit S.P.A. 6-AMINOSUBSTITUTED N-PYRROLYL-3-PYRIDAZINAMINES, THEIR PREPARATION AND PHARMACEUTICAL ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
NL7302391A (en) 1973-09-18
ZA73478B (en) 1973-10-31
FR2181820A1 (en) 1973-12-07
PH10526A (en) 1977-05-30
DE2308240A1 (en) 1973-09-20
JPS4899314A (en) 1973-12-15
AU5327073A (en) 1974-09-19
IL41405A (en) 1976-04-30
BE796759A (en) 1973-07-02
DE2308240C3 (en) 1978-07-13
CA1018458A (en) 1977-10-04
IE37171L (en) 1973-09-14
FR2181820B1 (en) 1975-10-31
DE2308240B2 (en) 1977-11-24
IL41405A0 (en) 1973-03-30
NL149704B (en) 1976-06-15
AU473956B2 (en) 1976-07-08
IE37171B1 (en) 1977-05-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee