ES437803A1 - Novel thiophene derivatives and their preparation - Google Patents

Novel thiophene derivatives and their preparation

Info

Publication number
ES437803A1
ES437803A1 ES437803A ES437803A ES437803A1 ES 437803 A1 ES437803 A1 ES 437803A1 ES 437803 A ES437803 A ES 437803A ES 437803 A ES437803 A ES 437803A ES 437803 A1 ES437803 A1 ES 437803A1
Authority
ES
Spain
Prior art keywords
thiophene derivatives
preparation
novel thiophene
chr5
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437803A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES437803A1 publication Critical patent/ES437803A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Thiophene derivatives of the formula < IMAGE > IN WHICH Rx is -S-CHR5-CONHOH or -S-CHR5-5-tetrazolyl in which R5 is H or alkyl of 1-6 carbon atoms and Ry is 0-2 of alkyl or alkoxy of 1-6 carbon atoms or halogen, and their pharmacologically acceptable salts with bases, possess antilipolytic activity.
ES437803A 1974-05-21 1975-05-20 Novel thiophene derivatives and their preparation Expired ES437803A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2424742A DE2424742C3 (en) 1974-05-21 1974-05-21 Thiophene derivatives Process for their preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
ES437803A1 true ES437803A1 (en) 1977-01-01

Family

ID=5916183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES437803A Expired ES437803A1 (en) 1974-05-21 1975-05-20 Novel thiophene derivatives and their preparation

Country Status (17)

Country Link
US (1) US4031236A (en)
JP (1) JPS50160267A (en)
AT (1) ATA385775A (en)
AU (1) AU8138475A (en)
BE (1) BE829307A (en)
DD (1) DD121111A5 (en)
DE (1) DE2424742C3 (en)
DK (1) DK136366C (en)
ES (1) ES437803A1 (en)
FI (1) FI751474A (en)
FR (1) FR2271816A1 (en)
GB (1) GB1512236A (en)
IL (1) IL47291A0 (en)
NL (1) NL7505571A (en)
NO (1) NO751779L (en)
SE (1) SE7505711L (en)
ZA (1) ZA753296B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2464953A1 (en) * 1979-09-06 1981-03-20 Sanofi Sa Alpha-2-thienyl-thio phenyl-acetamide derivs. - hypocholesterolaemics, antiinflammatories and analgesics prepd. by condensing amine with appropriate phenyl acetic acid chloride
GR78697B (en) * 1982-10-21 1984-09-27 Lilly Industries Ltd
US4885355A (en) * 1982-12-09 1989-12-05 The Dow Chemical Company Water-insoluble polymers from cyclic sulfonium compounds
GB8725260D0 (en) * 1987-10-28 1987-12-02 Lilly Industries Ltd Organic compounds
DK0970046T3 (en) * 1997-02-27 2004-04-13 Wyeth Corp N-Hydroxy-2- (alkyl, aryl or heteroarylsulfanyl, sulfinyl or sulfonyl) -3-substituted alkyl or heteroaryl amides as matrix metalloproteinase inhibitors
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2581626A (en) * 1948-10-06 1952-01-08 Socony Vacuum Oil Co Inc Thienylthio carboxylic acids and thienylthio carboxylic acid esters in lubricating compositions
US3560525A (en) * 1967-10-13 1971-02-02 Parke Davis & Co 5-phenyl-2-furanacetic acids,5-phenyl-2-thiopheneacetic acids,and their derivatives

Also Published As

Publication number Publication date
GB1512236A (en) 1978-05-24
US4031236A (en) 1977-06-21
AU8138475A (en) 1976-11-25
DE2424742C3 (en) 1982-04-22
BE829307A (en) 1975-11-21
DE2424742B2 (en) 1981-02-19
SE7505711L (en) 1975-11-24
FI751474A (en) 1975-11-22
DE2424742A1 (en) 1975-12-04
ZA753296B (en) 1976-04-28
FR2271816A1 (en) 1975-12-19
DK136366C (en) 1978-02-27
IL47291A0 (en) 1975-07-28
ATA385775A (en) 1978-03-15
NO751779L (en) 1975-11-24
NL7505571A (en) 1975-11-25
DK136366B (en) 1977-10-03
DK224175A (en) 1975-11-22
DD121111A5 (en) 1976-07-12
JPS50160267A (en) 1975-12-25

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