GB1168334A - New Pharmacologically Active Pyridazines - Google Patents
New Pharmacologically Active PyridazinesInfo
- Publication number
- GB1168334A GB1168334A GB3804/67A GB380467A GB1168334A GB 1168334 A GB1168334 A GB 1168334A GB 3804/67 A GB3804/67 A GB 3804/67A GB 380467 A GB380467 A GB 380467A GB 1168334 A GB1168334 A GB 1168334A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- possibly
- pyridazines
- substituted
- jan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1,168,334. 3 - Amino - 6 - pyridazylhydrazones. GRUPPO LEPETIT S.p.A. 5 Jan., 1968 [25 Jan., 1967], No. 3804/67. Heading C2C. The invention comprises compounds of formula wherein R<SP>1</SP> is H or alkyl (possibly OH-substituted), R<SP>11</SP> is Ph or alkyl (possibly OH-substituted), or NR<SP>1</SP>R<SP>11</SP> is a ring with possibly a further hetero-atom and alkyl substituents, R<SP>111</SP> is H or alkyl, and R<SP>1111</SP> is an alkyl, carboxy, aryl or optionally substituted furyl or thienyl, and a process for preparing them by reacting in an inert solvent the appropriate pyridazylhydrazine and carbonyl compound. All alkyl groups contain 1-8 C atoms. Therapeutic compositions with hypotensive activity comprise compounds of the above general formula with a pharmaceutically acceptable carrier.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3804/67A GB1168334A (en) | 1967-01-25 | 1967-01-25 | New Pharmacologically Active Pyridazines |
IL2924867A IL29248A (en) | 1967-01-25 | 1967-12-29 | Pharmacologically active 3-hydrazino-pyridazine derivatives |
NL6800466A NL6800466A (en) | 1967-01-25 | 1968-01-11 | |
DE19681695380 DE1695380C3 (en) | 1967-01-25 | 1968-01-12 | 3-hydrazinopyridazine derivatives and processes for their preparation |
SE54168A SE337382B (en) | 1967-01-25 | 1968-01-16 | |
FR1568058D FR1568058A (en) | 1967-01-25 | 1968-01-22 | |
FI16668A FI47663C (en) | 1967-01-25 | 1968-01-22 | Methods for preparing hypotensively active 3,6-disubstituted pyridazines. |
CH101668A CH471132A (en) | 1967-01-25 | 1968-01-23 | Process for the preparation of pharmacologically active pyridazine derivatives |
NO30368A NO120683B (en) | 1967-01-25 | 1968-01-24 | |
DK26468A DK117301B (en) | 1967-01-25 | 1968-01-24 | Analogous process for the preparation of 3,6-disubstituted pyridazines or acid addition salts thereof. |
BR19648568A BR6896485D0 (en) | 1967-01-25 | 1968-01-24 | NEW PHARMOCOLOGICALLY ACTIVE COMPOUNDS |
AT70768A AT271491B (en) | 1967-01-25 | 1968-01-24 | Process for the preparation of new 3,6-disubstituted pyridazines |
ES349741A ES349741A1 (en) | 1967-01-25 | 1968-01-25 | New Pharmacologically Active Pyridazines |
BE709868D BE709868A (en) | 1967-01-25 | 1968-01-25 | |
YU18468A YU32078B (en) | 1967-01-25 | 1968-01-25 | Postupak za dobijanje 3,6-disupstituisanog piridazina |
FR146475A FR7580M (en) | 1967-01-25 | 1968-03-29 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3804/67A GB1168334A (en) | 1967-01-25 | 1967-01-25 | New Pharmacologically Active Pyridazines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1168334A true GB1168334A (en) | 1969-10-22 |
Family
ID=9765208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3804/67A Expired GB1168334A (en) | 1967-01-25 | 1967-01-25 | New Pharmacologically Active Pyridazines |
Country Status (15)
Country | Link |
---|---|
AT (1) | AT271491B (en) |
BE (1) | BE709868A (en) |
BR (1) | BR6896485D0 (en) |
CH (1) | CH471132A (en) |
DE (1) | DE1695380C3 (en) |
DK (1) | DK117301B (en) |
ES (1) | ES349741A1 (en) |
FI (1) | FI47663C (en) |
FR (2) | FR1568058A (en) |
GB (1) | GB1168334A (en) |
IL (1) | IL29248A (en) |
NL (1) | NL6800466A (en) |
NO (1) | NO120683B (en) |
SE (1) | SE337382B (en) |
YU (1) | YU32078B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1298209A (en) * | 1968-12-30 | 1972-11-29 | Sandoz Ltd | Improvements in or relating to pyridazine derivatives |
IT1054107B (en) * | 1970-12-15 | 1981-11-10 | Isf Spa | NEW 3, HYDRAZINOPYRIDAZINE 6, SUBSTITUTED FOR ANTI-HYPERTEN SIVA ACTIVITIES AND THEIR PREPARATION |
ATE3294T1 (en) * | 1978-10-02 | 1983-05-15 | Gruppo Lepetit S.P.A. | 6-AMINOSUBSTITUTED N-PYRROLYL-3-PYRIDAZINAMINES, THEIR PREPARATION AND PHARMACEUTICAL ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM. |
-
1967
- 1967-01-25 GB GB3804/67A patent/GB1168334A/en not_active Expired
- 1967-12-29 IL IL2924867A patent/IL29248A/en unknown
-
1968
- 1968-01-11 NL NL6800466A patent/NL6800466A/xx unknown
- 1968-01-12 DE DE19681695380 patent/DE1695380C3/en not_active Expired
- 1968-01-16 SE SE54168A patent/SE337382B/xx unknown
- 1968-01-22 FI FI16668A patent/FI47663C/en active
- 1968-01-22 FR FR1568058D patent/FR1568058A/fr not_active Expired
- 1968-01-23 CH CH101668A patent/CH471132A/en not_active IP Right Cessation
- 1968-01-24 DK DK26468A patent/DK117301B/en not_active IP Right Cessation
- 1968-01-24 BR BR19648568A patent/BR6896485D0/en unknown
- 1968-01-24 NO NO30368A patent/NO120683B/no unknown
- 1968-01-24 AT AT70768A patent/AT271491B/en active
- 1968-01-25 YU YU18468A patent/YU32078B/en unknown
- 1968-01-25 ES ES349741A patent/ES349741A1/en not_active Expired
- 1968-01-25 BE BE709868D patent/BE709868A/xx not_active IP Right Cessation
- 1968-03-29 FR FR146475A patent/FR7580M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AT271491B (en) | 1969-06-10 |
BE709868A (en) | 1968-05-30 |
FI47663B (en) | 1973-10-31 |
CH471132A (en) | 1969-04-15 |
YU18468A (en) | 1973-10-31 |
NL6800466A (en) | 1968-07-26 |
BR6896485D0 (en) | 1973-05-10 |
DE1695380B2 (en) | 1973-11-08 |
FI47663C (en) | 1974-02-11 |
FR7580M (en) | 1970-01-05 |
IL29248A (en) | 1971-10-20 |
ES349741A1 (en) | 1969-04-01 |
NO120683B (en) | 1970-11-23 |
FR1568058A (en) | 1969-05-23 |
SE337382B (en) | 1971-08-09 |
YU32078B (en) | 1974-04-30 |
DK117301B (en) | 1970-04-13 |
DE1695380C3 (en) | 1974-07-04 |
DE1695380A1 (en) | 1972-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PE20 | Patent expired after termination of 20 years |