CA1117866A - Haemophilus influenzae vaccine - Google Patents

Haemophilus influenzae vaccine

Info

Publication number
CA1117866A
CA1117866A CA000310218A CA310218A CA1117866A CA 1117866 A CA1117866 A CA 1117866A CA 000310218 A CA000310218 A CA 000310218A CA 310218 A CA310218 A CA 310218A CA 1117866 A CA1117866 A CA 1117866A
Authority
CA
Canada
Prior art keywords
prp
combined vaccine
strain
vaccine according
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000310218A
Other languages
English (en)
French (fr)
Inventor
Joseph S.-C. Kuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/846,466 external-priority patent/US4196192A/en
Priority claimed from US05/846,488 external-priority patent/US4220717A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to CA000392369A priority Critical patent/CA1137901A/en
Application granted granted Critical
Publication of CA1117866A publication Critical patent/CA1117866A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000310218A 1977-10-28 1978-08-29 Haemophilus influenzae vaccine Expired CA1117866A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000392369A CA1137901A (en) 1977-12-22 1981-12-15 Isolation of capsular polysaccharide of haemophilus influenzae

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/846,466 US4196192A (en) 1977-10-28 1977-10-28 Combined Haemophilus influenzae type b and pertussis vaccine
US846,466 1977-10-28
US846,488 1977-12-22
US05/846,488 US4220717A (en) 1977-12-22 1977-12-22 Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b.

Publications (1)

Publication Number Publication Date
CA1117866A true CA1117866A (en) 1982-02-09

Family

ID=27126641

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000310218A Expired CA1117866A (en) 1977-10-28 1978-08-29 Haemophilus influenzae vaccine

Country Status (25)

Country Link
JP (1) JPS5480408A (it)
AR (1) AR218932A1 (it)
AU (1) AU520902B2 (it)
BE (1) BE871586A (it)
CA (1) CA1117866A (it)
CH (1) CH649781A5 (it)
DD (1) DD140701A5 (it)
DE (1) DE2845745A1 (it)
DK (1) DK154327C (it)
ES (1) ES474611A1 (it)
FI (1) FI63674C (it)
FR (1) FR2407000B1 (it)
GB (1) GB2007244B (it)
GR (1) GR73991B (it)
HU (1) HU178166B (it)
IE (1) IE47474B1 (it)
IL (1) IL55433A (it)
IT (1) IT1107570B (it)
NL (1) NL7810753A (it)
NO (1) NO149611C (it)
NZ (1) NZ188211A (it)
PH (1) PH15882A (it)
PL (1) PL210545A1 (it)
SE (1) SE430753B (it)
YU (1) YU250878A (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
CA1209036A (en) * 1982-08-20 1986-08-05 Joseph S.C. Kuo Combined haemophilus influenzae and diphtheria, pertussis, tetanus vaccine
US4744982A (en) * 1982-08-24 1988-05-17 Hunter Kenneth W Human monoclonal antibody reactive with polyribosylribitol phosphate
DE69113564T2 (de) * 1990-08-13 1996-05-30 American Cyanamid Co Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
CZ28694A3 (en) * 1991-08-16 1994-05-18 Merck & Co Inc Process for preparing capsular polysaccharide free of lipid and endotoxin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3395219A (en) * 1964-12-11 1968-07-30 Merck & Co Inc Process for production of pertussis antigen
NO116869B (it) * 1965-01-19 1969-06-02 Merck & Co Inc
US3465078A (en) * 1965-10-21 1969-09-02 Sydney Z Spiesel Method of recovering antigens from bordetella pertussis cells
NL174267B (nl) * 1969-05-20 Roussel Uclaf Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat.
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
FR2253499B1 (it) * 1973-12-10 1977-11-04 Fabre Sa Pierre
DE2461439C3 (de) * 1974-12-24 1980-03-20 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines schützenden Antigens von Bordetella Pertussis sowie jenes enthaltendes Mittel
US3978209A (en) * 1975-03-24 1976-08-31 Merck & Co., Inc. Endotoxin free meningococcus polysaccharides

Also Published As

Publication number Publication date
FI783269A (fi) 1979-04-29
IT1107570B (it) 1985-11-25
DE2845745A1 (de) 1979-05-10
AU520902B2 (en) 1982-03-04
NO149611C (no) 1984-05-23
NO783635L (no) 1979-05-02
IL55433A0 (en) 1978-10-31
HU178166B (en) 1982-03-28
JPS6231694B2 (it) 1987-07-09
BE871586A (fr) 1979-04-27
AU4108178A (en) 1980-05-01
DK154327C (da) 1989-04-03
IL55433A (en) 1982-09-30
SE430753B (sv) 1983-12-12
SE7811192L (sv) 1979-04-29
DE2845745C2 (it) 1987-10-01
FI63674B (fi) 1983-04-29
FR2407000A1 (it) 1979-05-25
GB2007244B (en) 1982-03-31
GR73991B (it) 1984-06-06
NO149611B (no) 1984-02-13
DD140701A5 (de) 1980-03-26
YU250878A (en) 1983-12-31
AR218932A1 (es) 1980-07-15
IE782146L (en) 1979-04-28
FI63674C (fi) 1983-08-10
FR2407000B1 (it) 1983-01-21
PH15882A (en) 1983-04-13
NZ188211A (en) 1984-09-28
CH649781A5 (de) 1985-06-14
JPS5480408A (en) 1979-06-27
IT7851621A0 (it) 1978-10-24
IE47474B1 (en) 1984-03-21
PL210545A1 (it) 1980-02-25
ES474611A1 (es) 1980-01-16
DK154327B (da) 1988-11-07
DK479578A (da) 1979-04-29
NL7810753A (nl) 1979-05-02
GB2007244A (en) 1979-05-16

Similar Documents

Publication Publication Date Title
US4220717A (en) Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b.
US4196192A (en) Combined Haemophilus influenzae type b and pertussis vaccine
EP0339667B1 (en) Hepatitis A,B,-combined adjuvanted vaccine
DE69736709T2 (de) Vielwertige dtp-polio-impfstoffe
US4197290A (en) Vaccine
JP4980868B2 (ja) 非細胞性百日咳ワクチンおよびその製造方法
JPH0231689A (ja) 百日咳トキシンの精製法
HU185404B (en) Process for preparing pertussis toxoide
Anderson et al. Isolation of the capsular polysaccharide from culture supernatant of Haemophilus influenzae type b
EP0407037B1 (en) Process for removing bacterial endotoxin from gram-negative polysaccharides
US4203971A (en) Neisseria gonorrhoeae vaccine
JPH0662436B2 (ja) 静注用免疫グロブリン製剤の製造方法
KR100401423B1 (ko) 혼합 백신의 제조 방법
CA1117866A (en) Haemophilus influenzae vaccine
US4239749A (en) Neisseria gonorrhoeae vaccine
EP0287732B1 (en) A method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
JPH02149530A (ja) 水酸化亜鉛または水酸化鉄をアジュバントとして含有する抗原溶液
HELTING et al. SEROTYPE DETERMINANT PROTEIN OF NEISSERIA MENINGITIDIS: Large Scale Preparation by Direct Detergent Treatment of the Bacterial Cells
KR810001317B1 (ko) 혼합백신의 제조방법
US3208909A (en) Anaerobic process for production of a gel-adsorbed anthrax immunizing antigen
CA1137901A (en) Isolation of capsular polysaccharide of haemophilus influenzae
JPS5872526A (ja) モノクロ−ルhbs抗体の製造方法
CN118373889A (zh) YjgB家族蛋白的制备方法及其作为驯化免疫激动剂类疫苗佐剂的用途
Fuenfer et al. 1094 THE EFFECT OF BETAMETHASONE ON THE CHEMOTACTIC RESPONSE OF NEONATAL NEUTROPHILS
JPH06316533A (ja) クレブシェラ莢膜多糖ワクチン

Legal Events

Date Code Title Description
MKEX Expiry