CA1109395A - Non-adhesive ionene quaternary polymer compositions and process - Google Patents

Non-adhesive ionene quaternary polymer compositions and process

Info

Publication number
CA1109395A
CA1109395A CA296,622A CA296622A CA1109395A CA 1109395 A CA1109395 A CA 1109395A CA 296622 A CA296622 A CA 296622A CA 1109395 A CA1109395 A CA 1109395A
Authority
CA
Canada
Prior art keywords
methyl
poly
iminio
adsorbate
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA296,622A
Other languages
English (en)
French (fr)
Inventor
Arthur F. Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1109395A publication Critical patent/CA1109395A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CA296,622A 1977-02-17 1978-02-08 Non-adhesive ionene quaternary polymer compositions and process Expired CA1109395A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76949177A 1977-02-17 1977-02-17
US769,491 1977-02-17

Publications (1)

Publication Number Publication Date
CA1109395A true CA1109395A (en) 1981-09-22

Family

ID=25085598

Family Applications (1)

Application Number Title Priority Date Filing Date
CA296,622A Expired CA1109395A (en) 1977-02-17 1978-02-08 Non-adhesive ionene quaternary polymer compositions and process

Country Status (26)

Country Link
JP (1) JPS53102958A (no)
AT (1) AT363173B (no)
AU (1) AU518127B2 (no)
BE (1) BE863930A (no)
CA (1) CA1109395A (no)
CH (1) CH636012A5 (no)
DE (1) DE2806707A1 (no)
DK (1) DK46578A (no)
ES (1) ES466892A1 (no)
FI (1) FI67483C (no)
FR (1) FR2381079A1 (no)
GB (1) GB1567294A (no)
GR (1) GR66100B (no)
HU (1) HU177685B (no)
IE (1) IE46408B1 (no)
IL (1) IL53978A (no)
IT (1) IT7848013A0 (no)
LU (1) LU79071A1 (no)
NL (1) NL7801240A (no)
NO (1) NO148838C (no)
NZ (1) NZ186399A (no)
PH (1) PH15263A (no)
PL (1) PL122299B1 (no)
PT (1) PT67663B (no)
SE (1) SE433170B (no)
ZA (1) ZA78913B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5709880A (en) * 1995-07-10 1998-01-20 Buckman Laboratories International, Inc. Method of making tabletized ionene polymers
EP0778027A3 (de) 1995-12-04 1998-04-01 Helmut Univ.-Prof. Dr. Wachter Verwendung von Kieselerde zur Herstellung von Arzneimitteln
JP4010585B2 (ja) * 1996-10-15 2007-11-21 久光製薬株式会社 陰イオン交換樹脂を含有する錠剤
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado

Also Published As

Publication number Publication date
FR2381079A1 (fr) 1978-09-15
NZ186399A (en) 1980-11-28
IE780332L (en) 1978-08-17
FI780296A (fi) 1978-08-18
PL122299B1 (en) 1982-07-31
SE433170B (sv) 1984-05-14
AU518127B2 (en) 1981-09-17
IE46408B1 (en) 1983-06-01
AU3309978A (en) 1979-08-16
ATA87978A (de) 1980-12-15
PH15263A (en) 1982-11-02
IT7848013A0 (it) 1978-02-10
HU177685B (en) 1981-12-28
FI67483B (fi) 1984-12-31
PT67663A (en) 1978-03-01
IL53978A0 (en) 1978-04-30
JPS53102958A (en) 1978-09-07
NO148838C (no) 1983-12-28
GB1567294A (en) 1980-05-14
ZA78913B (en) 1979-09-26
CH636012A5 (en) 1983-05-13
NO148838B (no) 1983-09-19
PL204642A1 (pl) 1979-06-04
IL53978A (en) 1981-03-31
NL7801240A (nl) 1978-08-21
BE863930A (fr) 1978-08-14
FR2381079B1 (no) 1981-09-11
ES466892A1 (es) 1979-08-16
DK46578A (da) 1978-08-18
GR66100B (no) 1981-01-16
PT67663B (en) 1980-03-03
DE2806707A1 (de) 1978-08-24
LU79071A1 (fr) 1978-09-28
FI67483C (fi) 1985-04-10
AT363173B (de) 1981-07-10
SE7801242L (sv) 1978-08-18
NO780367L (no) 1978-08-18

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