CA1106369A - Traduction non-disponible - Google Patents

Traduction non-disponible

Info

Publication number
CA1106369A
CA1106369A CA320,321A CA320321A CA1106369A CA 1106369 A CA1106369 A CA 1106369A CA 320321 A CA320321 A CA 320321A CA 1106369 A CA1106369 A CA 1106369A
Authority
CA
Canada
Prior art keywords
compound
beta
ethyl
epoxy
cyclobutylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA320,321A
Other languages
English (en)
Inventor
Robert N. Schut
Michael P. Kotick
David L. Leland
Joseph O. Polazzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Application granted granted Critical
Publication of CA1106369A publication Critical patent/CA1106369A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA320,321A 1978-02-10 1979-01-26 Traduction non-disponible Expired CA1106369A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87664078A 1978-02-10 1978-02-10
US876,640 1978-02-10
US91193978A 1978-06-02 1978-06-02
US911,939 1978-06-02

Publications (1)

Publication Number Publication Date
CA1106369A true CA1106369A (fr) 1981-08-04

Family

ID=27128411

Family Applications (1)

Application Number Title Priority Date Filing Date
CA320,321A Expired CA1106369A (fr) 1978-02-10 1979-01-26 Traduction non-disponible

Country Status (7)

Country Link
JP (1) JPS54117499A (fr)
AU (1) AU507873B2 (fr)
CA (1) CA1106369A (fr)
DE (1) DE2900918A1 (fr)
FR (1) FR2424277A1 (fr)
GB (1) GB2014141B (fr)
IL (1) IL56222A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4259329A (en) * 1979-10-17 1981-03-31 Miles Laboratories, Inc. 17-Cyclobutylmethyl-3-hydroxy-β-methyl-6-methylene morphinane, and methods of treating pain with them
US4275205A (en) * 1980-05-05 1981-06-23 Miles Laboratories, Inc. 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols
WO1983003197A1 (fr) * 1982-03-16 1983-09-29 Univ Rockefeller Procede pour reduire la dysmotilite gastro-intestinale
JPH0174251U (fr) * 1987-11-02 1989-05-19
JPH043470U (fr) * 1990-04-24 1992-01-13
US5194637A (en) * 1991-08-22 1993-03-16 Syracuse University Method and apparatus for synthesis of highly isomerically pure stereoisomers of glycidol derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1355143A (fr) * 1963-04-05 1964-03-13 Shionogi & Co Dérivés du morphinane et procédé de fabrication

Also Published As

Publication number Publication date
DE2900918A1 (de) 1979-08-16
JPS5757476B2 (fr) 1982-12-04
FR2424277B1 (fr) 1982-03-12
IL56222A (en) 1981-11-30
JPS54117499A (en) 1979-09-12
GB2014141A (en) 1979-08-22
GB2014141B (en) 1982-09-15
AU4409079A (en) 1979-08-16
FR2424277A1 (fr) 1979-11-23
AU507873B2 (en) 1980-02-28
IL56222A0 (en) 1979-03-12

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Legal Events

Date Code Title Description
MKEX Expiry
MKEX Expiry

Effective date: 19980804