IL56222A - 3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production - Google Patents
3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their productionInfo
- Publication number
- IL56222A IL56222A IL56222A IL5622278A IL56222A IL 56222 A IL56222 A IL 56222A IL 56222 A IL56222 A IL 56222A IL 5622278 A IL5622278 A IL 5622278A IL 56222 A IL56222 A IL 56222A
- Authority
- IL
- Israel
- Prior art keywords
- 8beta
- epoxymorphinan
- 5alpha
- methoxy
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87664078A | 1978-02-10 | 1978-02-10 | |
US91193978A | 1978-06-02 | 1978-06-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL56222A0 IL56222A0 (en) | 1979-03-12 |
IL56222A true IL56222A (en) | 1981-11-30 |
Family
ID=27128411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL56222A IL56222A (en) | 1978-02-10 | 1978-12-15 | 3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS54117499A (xx) |
AU (1) | AU507873B2 (xx) |
CA (1) | CA1106369A (xx) |
DE (1) | DE2900918A1 (xx) |
FR (1) | FR2424277A1 (xx) |
GB (1) | GB2014141B (xx) |
IL (1) | IL56222A (xx) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4272541A (en) * | 1978-06-02 | 1981-06-09 | Miles Laboratories, Inc. | 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them |
US4259329A (en) * | 1979-10-17 | 1981-03-31 | Miles Laboratories, Inc. | 17-Cyclobutylmethyl-3-hydroxy-β-methyl-6-methylene morphinane, and methods of treating pain with them |
US4275205A (en) * | 1980-05-05 | 1981-06-23 | Miles Laboratories, Inc. | 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols |
DE3381877D1 (de) * | 1982-03-16 | 1990-10-18 | Univ Rockefeller | Verwendung von opium antagonisten zur herstellung von arzneimitteln zur behebung gastro-intestinaler stoerungen. |
JPH0174251U (xx) * | 1987-11-02 | 1989-05-19 | ||
JPH043470U (xx) * | 1990-04-24 | 1992-01-13 | ||
US5194637A (en) * | 1991-08-22 | 1993-03-16 | Syracuse University | Method and apparatus for synthesis of highly isomerically pure stereoisomers of glycidol derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1355143A (fr) * | 1963-04-05 | 1964-03-13 | Shionogi & Co | Dérivés du morphinane et procédé de fabrication |
-
1978
- 1978-12-15 IL IL56222A patent/IL56222A/xx unknown
-
1979
- 1979-01-11 DE DE19792900918 patent/DE2900918A1/de not_active Withdrawn
- 1979-01-26 CA CA320,321A patent/CA1106369A/en not_active Expired
- 1979-02-06 GB GB7904029A patent/GB2014141B/en not_active Expired
- 1979-02-08 AU AU44090/79A patent/AU507873B2/en not_active Ceased
- 1979-02-08 JP JP1288479A patent/JPS54117499A/ja active Granted
- 1979-02-09 FR FR7903388A patent/FR2424277A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
GB2014141A (en) | 1979-08-22 |
FR2424277B1 (xx) | 1982-03-12 |
IL56222A0 (en) | 1979-03-12 |
AU507873B2 (en) | 1980-02-28 |
DE2900918A1 (de) | 1979-08-16 |
JPS5757476B2 (xx) | 1982-12-04 |
CA1106369A (en) | 1981-08-04 |
JPS54117499A (en) | 1979-09-12 |
AU4409079A (en) | 1979-08-16 |
FR2424277A1 (fr) | 1979-11-23 |
GB2014141B (en) | 1982-09-15 |
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