CA1106367A - Semi-synthetic 4"-erythromycin a derivatives - Google Patents

Semi-synthetic 4"-erythromycin a derivatives

Info

Publication number
CA1106367A
CA1106367A CA296,037A CA296037A CA1106367A CA 1106367 A CA1106367 A CA 1106367A CA 296037 A CA296037 A CA 296037A CA 1106367 A CA1106367 A CA 1106367A
Authority
CA
Canada
Prior art keywords
erythromycin
deoxy
reaction
product
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA296,037A
Other languages
English (en)
French (fr)
Inventor
Frank C. Sciavolino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/856,479 external-priority patent/US4150220A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Priority to CA381,481A priority Critical patent/CA1128506A/en
Application granted granted Critical
Publication of CA1106367A publication Critical patent/CA1106367A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA296,037A 1977-02-04 1978-02-02 Semi-synthetic 4"-erythromycin a derivatives Expired CA1106367A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA381,481A CA1128506A (en) 1977-02-04 1981-07-09 Semi-synthetic 4"-erythromycin a derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76548077A 1977-02-04 1977-02-04
US765,480 1977-02-04
US856,479 1977-12-01
US05/856,479 US4150220A (en) 1977-02-04 1977-12-01 Semi-synthetic 4"-erythromycin A derivatives

Publications (1)

Publication Number Publication Date
CA1106367A true CA1106367A (en) 1981-08-04

Family

ID=27117613

Family Applications (1)

Application Number Title Priority Date Filing Date
CA296,037A Expired CA1106367A (en) 1977-02-04 1978-02-02 Semi-synthetic 4"-erythromycin a derivatives

Country Status (30)

Country Link
JP (1) JPS5827798B2 (xx)
AR (1) AR222147A1 (xx)
AU (1) AU501298B1 (xx)
BG (2) BG32718A3 (xx)
CA (1) CA1106367A (xx)
CH (1) CH628906A5 (xx)
CS (1) CS221801B2 (xx)
DD (1) DD140048A5 (xx)
DE (1) DE2804507C2 (xx)
DK (1) DK148036C (xx)
ES (2) ES466057A1 (xx)
FI (1) FI780354A (xx)
FR (2) FR2379550A1 (xx)
GB (2) GB1585316A (xx)
GR (1) GR68691B (xx)
HU (1) HU182559B (xx)
IE (1) IE46661B1 (xx)
IL (2) IL53968A0 (xx)
IT (1) IT1094209B (xx)
LU (1) LU79004A1 (xx)
NL (1) NL176174C (xx)
NO (2) NO146472C (xx)
NZ (1) NZ186385A (xx)
PH (2) PH14421A (xx)
PL (1) PL116228B1 (xx)
PT (1) PT67568B (xx)
RO (4) RO77345A (xx)
SE (2) SE445223B (xx)
SU (1) SU927122A3 (xx)
YU (3) YU40913B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4124755A (en) * 1978-01-03 1978-11-07 Pfizer Inc. 11-Alkanoyl-4"-deoxy-4"-isonitrilo-oleandomycin derivatives
US4133950A (en) * 1978-01-03 1979-01-09 Pfizer Inc. 4"-Deoxy-4"-carbamate and dithiocarbamate derivatives of oleandomycin and its esters
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
US6407074B1 (en) 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3836519A (en) * 1973-05-04 1974-09-17 Abbott Lab Sulfonyl derivatives of erythromycin
US3884903A (en) * 1973-06-21 1975-05-20 Abbott Lab 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives

Also Published As

Publication number Publication date
FR2385735B1 (xx) 1980-10-24
GR68691B (xx) 1982-02-01
FR2385735A1 (fr) 1978-10-27
NO146472B (no) 1982-06-28
RO81622A (ro) 1983-04-29
HU182559B (en) 1984-02-28
IT7820005A0 (it) 1978-02-03
ES472429A1 (es) 1979-04-01
YU40799B (en) 1986-06-30
DK51878A (da) 1978-08-05
PH14421A (en) 1981-07-10
NL176174B (nl) 1984-10-01
NO150484C (no) 1984-10-24
IL53968A0 (en) 1978-04-30
SE8300870L (sv) 1983-02-16
PT67568B (en) 1979-06-18
RO79687A7 (ro) 1982-08-17
SE445223B (sv) 1986-06-09
GB1585315A (en) 1981-02-25
IE780239L (en) 1978-08-04
RO81622B (ro) 1983-04-30
NL176174C (nl) 1985-03-01
PT67568A (en) 1978-02-01
AU501298B1 (en) 1979-06-14
BG33159A3 (en) 1982-12-15
YU227983A (en) 1984-04-30
IL61997A0 (en) 1981-02-27
SE457086B (sv) 1988-11-28
CS221801B2 (en) 1983-04-29
FR2379550A1 (fr) 1978-09-01
LU79004A1 (fr) 1979-09-06
YU40798B (en) 1986-06-30
PL204428A1 (pl) 1979-06-04
RO79686A7 (ro) 1982-08-17
YU40913B (en) 1986-08-31
ES466057A1 (es) 1978-10-01
FR2379550B1 (xx) 1980-07-04
IE46661B1 (en) 1983-08-24
BG32718A3 (en) 1982-09-15
SE8300870D0 (sv) 1983-02-16
CH628906A5 (en) 1982-03-31
NO150484B (no) 1984-07-16
NO780389L (no) 1978-08-07
YU7378A (en) 1983-04-30
FI780354A (fi) 1978-08-05
DE2804507C2 (de) 1982-11-04
YU26583A (en) 1984-02-29
DD140048A5 (de) 1980-02-06
DE2804507A1 (de) 1978-08-10
GB1585316A (en) 1981-02-25
NO146472C (no) 1982-10-06
RO77345A (ro) 1981-08-17
DK148036C (da) 1985-07-15
NL7801262A (nl) 1978-08-08
DK148036B (da) 1985-02-11
SU927122A3 (ru) 1982-05-07
PL116228B1 (en) 1981-05-30
SE7800270L (sv) 1978-08-05
PH16675A (en) 1983-12-13
NO811913L (no) 1978-08-07
AR222147A1 (es) 1981-04-30
NZ186385A (en) 1980-10-08
IT1094209B (it) 1985-07-26
JPS5827798B2 (ja) 1983-06-11
JPS53101337A (en) 1978-09-04

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Legal Events

Date Code Title Description
MKEX Expiry