CA1103157A - Method of producing antibodies - Google Patents

Method of producing antibodies

Info

Publication number
CA1103157A
CA1103157A CA305,453A CA305453A CA1103157A CA 1103157 A CA1103157 A CA 1103157A CA 305453 A CA305453 A CA 305453A CA 1103157 A CA1103157 A CA 1103157A
Authority
CA
Canada
Prior art keywords
cells
virus
antibodies
hybrid
mouse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA305,453A
Other languages
English (en)
French (fr)
Inventor
Hilary Koprowski
Walter U. Gerhard
Carlo M. Croce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
Original Assignee
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Institute of Anatomy and Biology filed Critical Wistar Institute of Anatomy and Biology
Application granted granted Critical
Publication of CA1103157A publication Critical patent/CA1103157A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA305,453A 1977-06-15 1978-06-14 Method of producing antibodies Expired CA1103157A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80685777A 1977-06-15 1977-06-15
US806,857 1977-06-15

Publications (1)

Publication Number Publication Date
CA1103157A true CA1103157A (en) 1981-06-16

Family

ID=25194989

Family Applications (1)

Application Number Title Priority Date Filing Date
CA305,453A Expired CA1103157A (en) 1977-06-15 1978-06-14 Method of producing antibodies

Country Status (19)

Country Link
JP (2) JPS592276B2 (xx)
AU (1) AU525724B2 (xx)
BE (1) BE868099A (xx)
CA (1) CA1103157A (xx)
CH (1) CH640735A5 (xx)
DE (1) DE2826075A1 (xx)
DK (1) DK267378A (xx)
ES (1) ES470729A1 (xx)
FI (1) FI64952C (xx)
FR (1) FR2394607A1 (xx)
GB (1) GB2000186A (xx)
IL (1) IL54908A (xx)
IT (1) IT1096742B (xx)
LU (1) LU79812A1 (xx)
NL (1) NL7806471A (xx)
NO (1) NO782081L (xx)
PL (1) PL207652A1 (xx)
SE (1) SE7806729L (xx)
ZA (1) ZA783261B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008092B1 (de) 1978-08-10 1982-07-28 Schering Aktiengesellschaft Verfahren zur Gewinnung von Immunglobulin-E-Antikörpern der Maus, die hierfür verwendbaren Hybridzellinien und deren Herstellung; Verwendung der so erhaltenen Immunglobulin-E-Antikörper
CA1142466A (en) * 1979-01-09 1983-03-08 Cesar Milstein Cell lines
US4271145A (en) * 1979-10-22 1981-06-02 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
EP0038642B1 (en) * 1980-04-09 1989-02-08 National Research Development Corporation A monoclonal antibody against hepatitis b and its production, a hybridoma producing the monoclonal antibody and compositions containing it, the propagation of the hybridoma and the monoclonal antibody for use as an antiviral agent against hepatitus b and in isolating hepatitus b surface antigen from a sample
US5204095A (en) * 1980-04-09 1993-04-20 National Research Development Corporation Monoclonal antibodies against hepatitis B virus
NL185309C (nl) * 1980-07-28 1990-03-01 Akzo Nv Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
JPS5825439B2 (ja) * 1980-12-30 1983-05-27 株式会社林原生物化学研究所 ヒト副甲状腺ホルモンの製造方法
US4608337A (en) * 1980-11-07 1986-08-26 The Wistar Institute Human hybridomas and the production of human monoclonal antibodies by human hybridomas
JPS609795B2 (ja) * 1980-12-11 1985-03-13 株式会社林原生物化学研究所 ヒト上皮細胞成長因子の製造方法
WO1982003089A1 (en) * 1981-03-06 1982-09-16 Lennox Edwin Samuel Monoclonal antibody
CA1262238C (en) * 1982-09-30 1989-10-10 HUMAN MONOCLONAL ANTIBODIES AGAINST BACTERIAL TOXINS
JPH03271235A (ja) * 1983-04-08 1991-12-03 Kureha Chem Ind Co Ltd 抗カンジダ菌抗体分泌ハイブリドーマ
JPS60104020A (ja) * 1983-10-14 1985-06-08 メルク　エンド　カムパニー　インコーポレーテツド Ａ型肝炎‐タンパク質サブユニツト抗原
US4707442A (en) * 1983-10-24 1987-11-17 Board Of Regents, The University Of Texas System Hybrid cell line producing monoclonal antibody cytolytic to Trichomonas vaginalis
US4731237A (en) * 1983-11-07 1988-03-15 The Wistar Institute Immune response to virus induced by anti-idiotype antibodies
US5053224A (en) * 1983-11-07 1991-10-01 Hilary Koprowski Induction of antibody response to solid tumors with anti-idiotype antibodies
NL8401221A (nl) * 1984-04-16 1985-11-18 Innovi Nv Analytische toepassing van fagocyt-cellijnen.
JPS6140800A (ja) * 1984-07-27 1986-02-27 バイオテクノロジー　アンド　エクスペリメンタル　リサーチ　インコーポレーテツド 電気細胞融合法を用いたモノクローナル抗体の製造方法
EP0198086B1 (en) * 1984-09-28 1991-01-16 Teijin Limited Mouse human hybridoma producing antivirus human antibody, process for its preparation, and antivirus human monoclonal antibody
JPS6181782A (ja) * 1984-09-28 1986-04-25 Teijin Ltd 抗ウイルス・ヒト抗体を産生するマウス−ヒトハイブリド−マ及びその製造法並びにその使用方法
JPS6226300A (ja) * 1984-10-10 1987-02-04 セントコ−・インコ−ポレ−テツド Ｈｔｌｖ−３ｄｎａのクロ−ニングおよび発現
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
JPS61104796A (ja) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体の製造方法
JP2518607B2 (ja) * 1985-08-29 1996-07-24 雪印乳業株式会社 インフルエンザａ型ウイルスｈａ抗原に対するモノクロ―ナル抗体およびその作成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423505A (en) * 1964-10-31 1969-01-21 Univ Toronto Rabies vaccine and process for preparation thereof
US3585266A (en) * 1969-02-24 1971-06-15 Dow Chemical Co Live rabies virus vaccine and method for the production thereof

Also Published As

Publication number Publication date
FI64952C (fi) 1984-02-10
IT1096742B (it) 1985-08-26
JPS58101688A (ja) 1983-06-16
JPS592276B2 (ja) 1984-01-18
NO782081L (no) 1978-12-15
FR2394607A1 (fr) 1979-01-12
IL54908A0 (en) 1978-08-31
IL54908A (en) 1982-01-31
DE2826075A1 (de) 1979-02-15
AU525724B2 (en) 1982-11-25
SE7806729L (sv) 1978-12-16
NL7806471A (nl) 1978-12-19
DE2826075C2 (xx) 1987-08-06
LU79812A1 (de) 1978-12-07
PL207652A1 (pl) 1979-06-04
GB2000186A (en) 1979-01-04
DK267378A (da) 1978-12-16
FI781818A (fi) 1978-12-16
ZA783261B (en) 1979-06-27
FR2394607B1 (xx) 1983-12-30
JPS5417185A (en) 1979-02-08
FI64952B (fi) 1983-10-31
BE868099A (fr) 1978-10-02
ES470729A1 (es) 1979-01-16
IT7824577A0 (it) 1978-06-14
AU3708878A (en) 1979-12-20
CH640735A5 (de) 1984-01-31

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Legal Events

Date Code Title Description
MKEX Expiry