CA1100959A - Traduction non-disponible - Google Patents

Traduction non-disponible

Info

Publication number
CA1100959A
CA1100959A CA316,809A CA316809A CA1100959A CA 1100959 A CA1100959 A CA 1100959A CA 316809 A CA316809 A CA 316809A CA 1100959 A CA1100959 A CA 1100959A
Authority
CA
Canada
Prior art keywords
indolo
ethyl
product
quinolizidine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA316,809A
Other languages
English (en)
Inventor
Andre Buzas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Application granted granted Critical
Publication of CA1100959A publication Critical patent/CA1100959A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CA316,809A 1977-11-25 1978-11-24 Traduction non-disponible Expired CA1100959A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB49201 1977-11-25
GB4920177 1977-11-25

Publications (1)

Publication Number Publication Date
CA1100959A true CA1100959A (fr) 1981-05-12

Family

ID=10451538

Family Applications (1)

Application Number Title Priority Date Filing Date
CA316,809A Expired CA1100959A (fr) 1977-11-25 1978-11-24 Traduction non-disponible

Country Status (28)

Country Link
JP (1) JPS6147838B2 (fr)
AR (1) AR218514A1 (fr)
AT (1) AT372384B (fr)
AU (1) AU529108B2 (fr)
BE (1) BE872134A (fr)
CA (1) CA1100959A (fr)
CH (1) CH641181A5 (fr)
DE (1) DE2851028A1 (fr)
DK (1) DK154430C (fr)
EG (1) EG13683A (fr)
ES (1) ES475328A1 (fr)
FI (1) FI64372C (fr)
FR (2) FR2409755A1 (fr)
HK (1) HK60884A (fr)
IE (1) IE47518B1 (fr)
IN (1) IN151146B (fr)
IT (1) IT1160263B (fr)
LU (1) LU80576A1 (fr)
MX (1) MX5529E (fr)
MY (1) MY8500029A (fr)
NL (1) NL7811562A (fr)
NO (1) NO151288C (fr)
NZ (1) NZ188974A (fr)
PT (1) PT68825A (fr)
SE (2) SE431650B (fr)
SG (1) SG61182G (fr)
WO (1) WO1979000319A1 (fr)
ZA (1) ZA786426B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0079411B1 (fr) * 1981-11-18 1987-02-04 Thal, Claude Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique
FR2529552B1 (fr) * 1982-07-05 1985-09-27 Centre Nat Rech Scient Nouveau procede de preparation d'intermediaires de synthese de la vindoline et intermediaires de synthese
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
DK0704439T3 (da) * 1993-06-18 2001-10-08 Fujisawa Pharmaceutical Co Hidtil ukendt mellemprodukt til syntetisk anvendelse og fremgangsmåde til fremstilling af aminopiperazinderivater
FR2713643B1 (fr) * 1993-12-14 1996-06-07 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
ES2324530T5 (es) † 2002-06-24 2019-10-25 Saint Gobain Isover Panel aislante para conductos de distribución
FR2911141B1 (fr) * 2007-01-05 2009-02-20 Servier Lab Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911142A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Nouveaux derives aminopyrrolo[1,2-a]indole et aminopyridazino[1,6-a]indole,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911143A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167366B (fr) * 1972-09-06 1975-09-27
BE802387A (fr) * 1973-07-16 1973-11-16 Omnium Chimique Sa Procede de preparation de la vincamone et de l'epi-21 vincamone a partir de la tabersonine et derives indoliques nouveaux.
HU169916B (fr) * 1974-09-27 1977-02-28
HU171165B (hu) * 1974-11-26 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh oktagidro-indolo-skobka-2,3-a-skobka zakryta-kinolizina
FR2315277A1 (fr) * 1975-06-25 1977-01-21 Anvar Nouveaux derives pentacycliques, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
LU80576A1 (fr) 1979-03-22
IT1160263B (it) 1987-03-11
PT68825A (en) 1978-12-01
NO783958L (no) 1979-05-28
EG13683A (en) 1982-09-30
IE47518B1 (en) 1984-04-04
MY8500029A (en) 1985-12-31
AR218514A1 (es) 1980-06-13
DK524978A (da) 1979-05-26
FR2409755B1 (fr) 1980-08-01
JPS6147838B2 (fr) 1986-10-21
DE2851028C2 (fr) 1990-05-03
HK60884A (en) 1984-08-10
CH641181A5 (fr) 1984-02-15
SE431650B (sv) 1984-02-20
NL7811562A (nl) 1979-05-29
FR2423492B1 (fr) 1980-12-05
SE7906287L (sv) 1979-07-23
AT372384B (de) 1983-09-26
ZA786426B (en) 1979-10-31
SE8007845L (sv) 1980-11-07
NZ188974A (en) 1989-10-27
MX5529E (es) 1983-09-23
DK154430B (da) 1988-11-14
WO1979000319A1 (fr) 1979-06-14
ATA837478A (de) 1983-02-15
JPS54500053A (fr) 1979-11-08
FI783581A (fi) 1979-05-26
IT7830171A0 (it) 1978-11-24
ES475328A1 (es) 1979-04-01
DK154430C (da) 1989-04-17
IE782328L (en) 1979-05-25
AU4187478A (en) 1979-05-31
SE435622B (sv) 1984-10-08
DE2851028A1 (de) 1979-05-31
NO151288B (no) 1984-12-03
FR2423492A1 (fr) 1979-11-16
FR2409755A1 (fr) 1979-06-22
IN151146B (fr) 1983-02-26
SG61182G (en) 1985-02-15
NO151288C (no) 1985-03-13
BE872134A (fr) 1979-03-16
AU529108B2 (en) 1983-05-26
FI64372B (fi) 1983-07-29
FI64372C (fi) 1983-11-10

Similar Documents

Publication Publication Date Title
CA1100959A (fr) Traduction non-disponible
US5380861A (en) Process for preparing pyridine 2-carboxamides
HU178593B (en) Process for producing 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocine derivatives
US4066665A (en) 2-Alkylamino-α-phenyl-1-cyclohexene-1-methyleneimine, its salts and preparation
WO2000062782A1 (fr) Nouvelle synthese et cristallisation de composes contenant de la piperazine
JPS6036436B2 (ja) １０‐〔ω‐（ベンゾイルピペリジニル）アルキル〕フエノチアジアジンおよびその酸付加塩ならびにそれらの製造法
HU182636B (en) Process for producing pyrazolo-imidazol derivatives
WO1998005657A1 (fr) 2,3-dihydro-1,4-benzothiazepines, leur preparation et leur utilisation comme produits intermediaires
US4353911A (en) Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow
US5461157A (en) Process for preparing pyrrolidinylacetamide derivatives
US6576764B2 (en) Synthesis and crystallization of piperazine ring-containing compounds
US3933836A (en) Pyridinylidene guanidines
AU613589B2 (en) Compounds useful as intermediates for the production of substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols
US3948919A (en) 2-Hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butylaminoethyl)pyridine preparation and intermediate compounds
GB1592295A (en) Sulphamoylbenzoic acids
NO147838B (no) Mellomprodukt til bruk ved fremstilling av det hypotensive middel 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimetoksykinazolin
KR100525703B1 (ko) 1-부틸-4-피페리디닐메틸아민의 제법
EP0294615B1 (fr) Intermédiaires cyclobutène 3,4 dione et leur utilisation dans la préparation d'antagonistes d'histamine H2
CA1167439A (fr) Composes pentacycliques, leur preparation et leur emploi
US4062891A (en) N-formyl-2,3,5,6-dibenzobicyclo[5.1.0]octan-4-methylamine
GB2051048A (en) Geminal Dihalogen Derivatives of Condensed Pyrimidin-4-one Compounds their Preparation and Pharmaceutical Compositions Containing them
US4051127A (en) Preparation of benzodiazepine derivatives
AU781221B2 (en) Novel synthesis and crystallization of piperazine ring-containing compounds
US5151544A (en) Intermediates in the preparation of chiral spirofluorenehydantoins
US5932767A (en) Process for preparing dibenzocycloheptene compounds

Legal Events

Date Code Title Description
MKEX Expiry