CA1096387A - Process for the production of polymorph of cimetidine - Google Patents

Process for the production of polymorph of cimetidine

Info

Publication number
CA1096387A
CA1096387A CA287,087A CA287087A CA1096387A CA 1096387 A CA1096387 A CA 1096387A CA 287087 A CA287087 A CA 287087A CA 1096387 A CA1096387 A CA 1096387A
Authority
CA
Canada
Prior art keywords
cimetidine
suspension
solvent
strong
peak
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA287,087A
Other languages
English (en)
French (fr)
Inventor
Patrick M.G. Bavin
James C.P. Sly
Richard J. Ward
Geoffrey D. Tovey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline & French Laboratories Ltd
Original Assignee
Smith Kline & French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB3906576A external-priority patent/GB1543238A/en
Application filed by Smith Kline & French Laboratories Ltd filed Critical Smith Kline & French Laboratories Ltd
Application granted granted Critical
Publication of CA1096387A publication Critical patent/CA1096387A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA287,087A 1976-09-21 1977-09-20 Process for the production of polymorph of cimetidine Expired CA1096387A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB39065/76 1976-09-21
GB3906576A GB1543238A (en) 1976-09-21 1976-09-21 Polymorph of cimetidine
GB2716/77 1977-01-24
GB271677 1977-01-24

Publications (1)

Publication Number Publication Date
CA1096387A true CA1096387A (en) 1981-02-24

Family

ID=26237687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA287,087A Expired CA1096387A (en) 1976-09-21 1977-09-20 Process for the production of polymorph of cimetidine

Country Status (10)

Country Link
JP (1) JPS5340771A (online.php)
AU (1) AU510629B2 (online.php)
BE (1) BE858432A (online.php)
CA (1) CA1096387A (online.php)
DE (1) DE2742531A1 (online.php)
FR (1) FR2364906A1 (online.php)
IE (1) IE45873B1 (online.php)
IL (1) IL52784A (online.php)
LU (1) LU78142A1 (online.php)
NZ (1) NZ184893A (online.php)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579954A (en) * 1981-06-26 1986-04-01 Richter Gedeon Vegyeszeti Gyar Rt. Cimetidine monohydrate

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56104868A (en) * 1980-01-24 1981-08-20 Fujimoto Seiyaku Kk Conversion between polymorphous crystals of cimetidine
JPS56164122A (en) * 1980-05-21 1981-12-17 Fujimoto Seiyaku Kk Drug composition comprising cimetidine as main agent
HU185457B (en) * 1981-09-25 1985-02-28 Richter Gedeon Vegyeszet Process for preparating cimetidine-z
JPS5888366A (ja) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk グアニジン誘導体の製造法
JPS59128375A (ja) * 1983-01-10 1984-07-24 Tokawa Tetsuo イミダゾ−ル系化合物の製法
JPS59130274A (ja) * 1983-01-14 1984-07-26 Tokawa Tetsuo イミダゾ−ル系化合物の製法
JPS59130273A (ja) * 1983-01-14 1984-07-26 Tokawa Tetsuo イミダゾ−ル系化合物の製造法
HU196184B (en) * 1986-09-11 1988-10-28 Richter Gedeon Vegyeszet Process for producing cimetidine-a modification

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
CA1064940A (en) * 1975-08-20 1979-10-23 Wilford L. Mendelson Reduction process for the preparation of 4-(hydroxymethyl) imidazole compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579954A (en) * 1981-06-26 1986-04-01 Richter Gedeon Vegyeszeti Gyar Rt. Cimetidine monohydrate

Also Published As

Publication number Publication date
IE45873L (en) 1978-07-24
IL52784A0 (en) 1977-10-31
AU2879277A (en) 1979-03-22
DE2742531A1 (de) 1978-03-23
IE45873B1 (en) 1982-12-15
AU510629B2 (en) 1980-07-03
FR2364906A1 (fr) 1978-04-14
JPS5340771A (en) 1978-04-13
LU78142A1 (online.php) 1978-01-17
JPS6222967B2 (online.php) 1987-05-20
NZ184893A (en) 1980-11-28
IL52784A (en) 1980-09-16
BE858432A (fr) 1978-03-06

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Legal Events

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