CA1084504A - Ester tetra-nicotinique de la papaveroline et procede de production - Google Patents

Ester tetra-nicotinique de la papaveroline et procede de production

Info

Publication number
CA1084504A
CA1084504A CA304,384A CA304384A CA1084504A CA 1084504 A CA1084504 A CA 1084504A CA 304384 A CA304384 A CA 304384A CA 1084504 A CA1084504 A CA 1084504A
Authority
CA
Canada
Prior art keywords
papaveroline
tetra
nicotinic
ester
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA304,384A
Other languages
English (en)
Inventor
Massimo Fazzini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scharper SpA Per L'industria Farmaceutica
Original Assignee
Scharper SpA Per L'industria Farmaceutica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scharper SpA Per L'industria Farmaceutica filed Critical Scharper SpA Per L'industria Farmaceutica
Application granted granted Critical
Publication of CA1084504A publication Critical patent/CA1084504A/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA304,384A 1977-05-30 1978-05-30 Ester tetra-nicotinique de la papaveroline et procede de production Expired CA1084504A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT24141A/77 1977-05-30
IT24141/77A IT1143667B (it) 1977-05-30 1977-05-30 Derivato paraverolinico ad azione duratura e procedimento per ottenerlo

Publications (1)

Publication Number Publication Date
CA1084504A true CA1084504A (fr) 1980-08-26

Family

ID=11212187

Family Applications (1)

Application Number Title Priority Date Filing Date
CA304,384A Expired CA1084504A (fr) 1977-05-30 1978-05-30 Ester tetra-nicotinique de la papaveroline et procede de production

Country Status (13)

Country Link
JP (1) JPS53149982A (fr)
BE (1) BE867515A (fr)
BR (1) BR7803416A (fr)
CA (1) CA1084504A (fr)
CH (1) CH633446A5 (fr)
DE (1) DE2822186A1 (fr)
ES (1) ES470343A1 (fr)
FR (1) FR2392987A1 (fr)
GB (1) GB1593598A (fr)
GR (1) GR63731B (fr)
IT (1) IT1143667B (fr)
MX (1) MX5515E (fr)
PT (1) PT68115A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77027C (fi) * 1979-07-19 1989-01-10 Andre Buzas Saett framstaellning av farmakologiskt verksam 1-/1-(3,4-dimetoxifenyl)-3-amino-propyl/-6,7-dimetoxi- isokinolinfoerening.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1175246B (de) * 1959-12-14 1964-08-06 Orsymonde Fa Verfahren zur Herstellung des Dimethylpapa-verolin-bis-nicotinsaeureesters und seines sauren Dimaleats
FR794M (fr) * 1960-12-02 1961-09-11

Also Published As

Publication number Publication date
GR63731B (en) 1979-12-04
JPS572715B2 (fr) 1982-01-18
IT1143667B (it) 1986-10-22
ES470343A1 (es) 1979-01-01
FR2392987B1 (fr) 1982-04-23
GB1593598A (en) 1981-07-22
CH633446A5 (en) 1982-12-15
DE2822186A1 (de) 1978-12-14
BR7803416A (pt) 1979-01-02
JPS53149982A (en) 1978-12-27
MX5515E (es) 1983-09-14
BE867515A (fr) 1978-09-18
FR2392987A1 (fr) 1978-12-29
PT68115A (en) 1978-06-01

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