CA1069070A - Water insoluble biologically active compounds and process for their manufacture - Google Patents

Water insoluble biologically active compounds and process for their manufacture

Info

Publication number
CA1069070A
CA1069070A CA266,092A CA266092A CA1069070A CA 1069070 A CA1069070 A CA 1069070A CA 266092 A CA266092 A CA 266092A CA 1069070 A CA1069070 A CA 1069070A
Authority
CA
Canada
Prior art keywords
copolymer
biologically active
active substance
groups
vinylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA266,092A
Other languages
English (en)
French (fr)
Inventor
Heinrich Huemer
Tibor Toth
Rudolf Schmidtberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of CA1069070A publication Critical patent/CA1069070A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/091—Phenol resins; Amino resins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/50—Chemical modification of a polymer wherein the polymer is a copolymer and the modification is taking place only on one or more of the monomers present in minority

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CA266,092A 1975-11-22 1976-11-19 Water insoluble biologically active compounds and process for their manufacture Expired CA1069070A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2552510A DE2552510C3 (de) 1975-11-22 1975-11-22 Biologisch aktive Verbindungen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
CA1069070A true CA1069070A (en) 1980-01-01

Family

ID=5962419

Family Applications (1)

Application Number Title Priority Date Filing Date
CA266,092A Expired CA1069070A (en) 1975-11-22 1976-11-19 Water insoluble biologically active compounds and process for their manufacture

Country Status (20)

Country Link
JP (1) JPS6048524B2 (de)
AT (1) AT358275B (de)
AU (1) AU513890B2 (de)
BE (1) BE848601A (de)
CA (1) CA1069070A (de)
CH (1) CH636628A5 (de)
DE (1) DE2552510C3 (de)
DK (1) DK522976A (de)
ES (1) ES453362A1 (de)
FI (1) FI763314A (de)
FR (1) FR2332287A1 (de)
GB (1) GB1571182A (de)
IL (1) IL50940A (de)
IT (1) IT1121742B (de)
LU (1) LU76243A1 (de)
NL (1) NL7612771A (de)
NO (1) NO763975L (de)
SE (1) SE430066B (de)
YU (1) YU283676A (de)
ZA (1) ZA766942B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6929955B2 (en) 1997-04-14 2005-08-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Berlin Interactive system for presenting and eliminating substances

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210722A (en) * 1977-11-14 1980-07-01 Minnesota Mining And Manufacturing Company Protein immobilizer
DE2757206A1 (de) * 1977-12-22 1979-07-05 Basf Ag Polyamidacetale
GB2043996B (en) * 1978-12-27 1983-09-07 Nihon Dempa Kogyo Co Thickness shear quartz crystal oscillator
FR2450263A1 (fr) * 1979-02-28 1980-09-26 Dow Chemical Co Procede pour coupler une proteine sur un latex portant des groupes epoxyde et produits obtenus par ce procede
EP0015473A1 (de) * 1979-02-28 1980-09-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zum Immobilisieren von Zellen
DE3145082A1 (de) * 1981-11-13 1983-05-19 Behringwerke Ag, 3550 Marburg "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung"
JPS58209984A (ja) * 1982-05-28 1983-12-07 Japan Synthetic Rubber Co Ltd 粒子状重合体よりなる担体
DE3243591A1 (de) * 1982-11-25 1984-05-30 Hoechst Ag, 6230 Frankfurt Vinylencarbonat-polymerysate, verfahren zu ihrer herstellung und ihre anwendung
DE3344912A1 (de) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt Vernetzte polymerisate, verfahren zu ihrer herstellung und ihre anwendung
SE8401437D0 (sv) * 1984-03-14 1984-03-14 Sven Gothe Ytmodifierade plastytor och dess tillempningar for immunoassays (ia)
DE3413904A1 (de) * 1984-04-13 1985-10-24 Hoechst Ag, 6230 Frankfurt Polymerisate auf basis von polyvinylencarbonat und/oder polyhydroxymethylen, verfahren zu ihrer herstellung und ihre anwendung
GB8423228D0 (en) * 1984-09-14 1984-10-17 Unilever Plc Specific binding materials
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
DE3637421C1 (de) * 1986-11-03 1987-10-29 Nerbe Plus Ges Fuer Medizinisc Reaktionsgefaess fuer die Blutgerinnungsreaktion
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
JP2001247738A (ja) * 2000-03-06 2001-09-11 Unitika Chem Co Ltd ポリビニルアルコール系樹脂組成物およびそれを主成分とする紙コート剤
JP6405669B2 (ja) * 2014-03-31 2018-10-17 東ソー株式会社 新規重合体、およびそれを有する細胞培養基材
CN108264604B (zh) * 2016-12-30 2020-08-11 北京爱普聚合科技有限公司 一种干法压裂液减阻增稠剂及其制备方法
EP3502274A1 (de) * 2017-12-22 2019-06-26 Attomol GmbH Probenträger und verfahren zu dessen herstellung
CN110504452B (zh) * 2019-09-04 2022-06-21 中国科学院青岛生物能源与过程研究所 一种高剥离强度的聚合物粘结剂及其在二次锂电池中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE810605A (fr) * 1973-03-01 1974-05-29 Enzymes et autres proteines liees a des supports polymeriques contenant des unites de carbonate de vinylene
ES437153A1 (es) * 1974-05-06 1977-04-16 Marburgnlahn Procedimiento para la preparacion de un compuesto biologica-mente activo a base de poli(hidroximetileno) o poli(carbona-to de vinileno).

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6929955B2 (en) 1997-04-14 2005-08-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Berlin Interactive system for presenting and eliminating substances
US7494824B2 (en) 1997-04-14 2009-02-24 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V., Berlin Interactive system for presenting and eliminating substances

Also Published As

Publication number Publication date
FI763314A (de) 1977-05-23
FR2332287A1 (fr) 1977-06-17
IL50940A0 (en) 1977-01-31
YU283676A (en) 1982-06-30
LU76243A1 (de) 1977-06-07
FR2332287B1 (de) 1982-11-12
ZA766942B (en) 1977-10-26
DE2552510A1 (de) 1977-06-30
DK522976A (da) 1977-05-23
JPS5265596A (en) 1977-05-31
JPS6048524B2 (ja) 1985-10-28
IL50940A (en) 1980-03-31
AU513890B2 (en) 1981-01-15
GB1571182A (en) 1980-07-09
AT358275B (de) 1980-08-25
SE430066B (sv) 1983-10-17
ES453362A1 (es) 1977-11-16
CH636628A5 (en) 1983-06-15
DE2552510B2 (de) 1980-06-04
AU1981776A (en) 1978-05-25
NL7612771A (nl) 1977-05-24
BE848601A (fr) 1977-05-23
ATA863176A (de) 1980-01-15
SE7612998L (sv) 1977-05-23
NO763975L (de) 1977-05-24
DE2552510C3 (de) 1981-02-19
IT1121742B (it) 1986-04-23

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