CA1064943A - Optical resolution of 1-t-butylamino-2,3-dihydroxypropane - Google Patents

Optical resolution of 1-t-butylamino-2,3-dihydroxypropane

Info

Publication number
CA1064943A
CA1064943A CA241,257A CA241257A CA1064943A CA 1064943 A CA1064943 A CA 1064943A CA 241257 A CA241257 A CA 241257A CA 1064943 A CA1064943 A CA 1064943A
Authority
CA
Canada
Prior art keywords
dihydroxypropane
butylamino
diastereoisomer
acid
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA241,257A
Other languages
English (en)
French (fr)
Inventor
Donald F. Reinhold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1064943A publication Critical patent/CA1064943A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA241,257A 1974-12-13 1975-12-08 Optical resolution of 1-t-butylamino-2,3-dihydroxypropane Expired CA1064943A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53254774A 1974-12-13 1974-12-13
US61594175A 1975-09-25 1975-09-25

Publications (1)

Publication Number Publication Date
CA1064943A true CA1064943A (en) 1979-10-23

Family

ID=27063872

Family Applications (1)

Application Number Title Priority Date Filing Date
CA241,257A Expired CA1064943A (en) 1974-12-13 1975-12-08 Optical resolution of 1-t-butylamino-2,3-dihydroxypropane

Country Status (10)

Country Link
JP (1) JPS51118711A (enExample)
AU (1) AU510799B2 (enExample)
CA (1) CA1064943A (enExample)
DE (1) DE2556040C2 (enExample)
DK (1) DK532575A (enExample)
FR (2) FR2294151A1 (enExample)
GB (1) GB1470030A (enExample)
IE (1) IE42206B1 (enExample)
NL (1) NL7513818A (enExample)
SE (1) SE435499B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5931693A (ja) * 1982-08-13 1984-02-20 Kanegafuchi Chem Ind Co Ltd 光学活性オキサゾリジノン誘導体の製造方法
JPH01149775A (ja) * 1987-12-07 1989-06-12 Kawaken Fine Chem Co Ltd 光学活性２−メチルピペラジンの製造方法
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
IN187238B (enExample) * 1995-06-30 2002-03-09 Astra Ab
JP7603368B2 (ja) 2016-03-25 2024-12-20 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ （２ｒ，６ｒ）－ヒドロキシノルケタミン塩酸塩の結晶形態

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528267A (en) * 1950-10-31 Eobeet j
US3116332A (en) * 1958-10-17 1963-12-31 Du Pont Resolution of racemic aminoisopropanol

Also Published As

Publication number Publication date
FR2303790B1 (enExample) 1980-07-18
FR2294151A1 (fr) 1976-07-09
AU510799B2 (en) 1980-07-17
DE2556040A1 (de) 1976-06-16
JPS51118711A (en) 1976-10-18
SE7513307L (sv) 1976-06-14
GB1470030A (en) 1977-04-14
DE2556040C2 (de) 1986-05-07
SE435499B (sv) 1984-10-01
DK532575A (da) 1976-06-14
IE42206L (en) 1976-06-13
FR2303790A1 (fr) 1976-10-08
AU8722075A (en) 1977-06-09
NL7513818A (nl) 1976-06-15
IE42206B1 (en) 1980-06-18
FR2294151B1 (enExample) 1979-04-06

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