CA1063936A - Preparation of amorphous solid of macrolide antibiotics - Google Patents

Preparation of amorphous solid of macrolide antibiotics

Info

Publication number
CA1063936A
CA1063936A CA249,607A CA249607A CA1063936A CA 1063936 A CA1063936 A CA 1063936A CA 249607 A CA249607 A CA 249607A CA 1063936 A CA1063936 A CA 1063936A
Authority
CA
Canada
Prior art keywords
cellulose
amorphous solid
macrolide
antibiotic
macrolide antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA249,607A
Other languages
English (en)
French (fr)
Inventor
Takeshi Mayama
Toshiyuki Kobayashi
Toyomi Sato
Akira Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of CA1063936A publication Critical patent/CA1063936A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA249,607A 1975-04-08 1976-04-05 Preparation of amorphous solid of macrolide antibiotics Expired CA1063936A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Publications (1)

Publication Number Publication Date
CA1063936A true CA1063936A (en) 1979-10-09

Family

ID=12618972

Family Applications (1)

Application Number Title Priority Date Filing Date
CA249,607A Expired CA1063936A (en) 1975-04-08 1976-04-05 Preparation of amorphous solid of macrolide antibiotics

Country Status (8)

Country Link
JP (1) JPS51118816A (de)
CA (1) CA1063936A (de)
DE (1) DE2615403C2 (de)
ES (1) ES446801A1 (de)
FR (1) FR2306705A1 (de)
GB (1) GB1534070A (de)
MX (1) MX3401E (de)
NL (1) NL176270C (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819844B2 (ja) * 1978-07-13 1983-04-20 三菱自動車工業株式会社 機関用燃料供給装置
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4767789A (en) * 1986-10-21 1988-08-30 American Home Products Corporation (Del.) Spray dried acetaminophen
GB9713730D0 (en) * 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers

Also Published As

Publication number Publication date
DE2615403C2 (de) 1982-07-15
NL176270B (nl) 1984-10-16
ES446801A1 (es) 1977-06-01
NL7603635A (nl) 1976-10-12
NL176270C (nl) 1985-03-18
MX3401E (es) 1980-10-30
JPS51118816A (en) 1976-10-19
GB1534070A (en) 1978-11-29
JPS5545042B2 (de) 1980-11-15
FR2306705A1 (fr) 1976-11-05
FR2306705B1 (de) 1980-07-18
DE2615403A1 (de) 1976-10-28

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