CA1041997A - Immunoglobulin derivatives and process for the preparation thereof - Google Patents

Immunoglobulin derivatives and process for the preparation thereof

Info

Publication number
CA1041997A
CA1041997A CA221,623A CA221623A CA1041997A CA 1041997 A CA1041997 A CA 1041997A CA 221623 A CA221623 A CA 221623A CA 1041997 A CA1041997 A CA 1041997A
Authority
CA
Canada
Prior art keywords
immunoglobulin
disulfide bonds
reaction
sulfonated
cleaved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA221,623A
Other languages
English (en)
French (fr)
Other versions
CA221623S (en
Inventor
Katsuhiko Tomibe
Yasuhiko Masuho
Kimihiko Matsuzawa
Sachio Ishimoto
Kazuo Satake
Tsuneo Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2634174A external-priority patent/JPS5417721B2/ja
Priority claimed from JP7127474A external-priority patent/JPS511630A/ja
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of CA1041997A publication Critical patent/CA1041997A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA221,623A 1974-03-08 1975-03-07 Immunoglobulin derivatives and process for the preparation thereof Expired CA1041997A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2634174A JPS5417721B2 (enFirst) 1974-03-08 1974-03-08
JP7127474A JPS511630A (ja) 1974-06-24 1974-06-24 Jomyakuchushayomenekiguroburinno seizoho

Publications (1)

Publication Number Publication Date
CA1041997A true CA1041997A (en) 1978-11-07

Family

ID=26364115

Family Applications (1)

Application Number Title Priority Date Filing Date
CA221,623A Expired CA1041997A (en) 1974-03-08 1975-03-07 Immunoglobulin derivatives and process for the preparation thereof

Country Status (12)

Country Link
US (1) US4059571A (enFirst)
CA (1) CA1041997A (enFirst)
CH (1) CH614426A5 (enFirst)
DD (1) DD118655A5 (enFirst)
DE (2) DE2560155C2 (enFirst)
DK (1) DK141432B (enFirst)
FR (1) FR2262996B1 (enFirst)
GB (1) GB1497928A (enFirst)
IN (1) IN138636B (enFirst)
NL (1) NL167167C (enFirst)
NO (1) NO144111C (enFirst)
SE (1) SE403703B (enFirst)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658334C3 (de) * 1976-12-23 1987-05-07 Behringwerke Ag, 3550 Marburg Verfahren zum Herstellen von Immunglobulinpräparationen mit verminderter Komplementaktivität und ein diese enthaltendes Arzneimittel
JPS5598117A (en) * 1979-01-17 1980-07-25 Chemo Sero Therapeut Res Inst Purification of gamma-globulin derivative
DE2953674C2 (de) * 1979-05-23 1986-04-24 Teijin Ltd., Osaka Verfahren zur Herstellung von menschlichen Immungammaglobulinderivaten
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
CA1153695A (en) * 1979-08-30 1983-09-13 Syoji Ono S-sulfonated immunoglobulin composition having a high monomer content and a process for production thereof
JPS56113713A (en) * 1980-02-14 1981-09-07 Chemo Sero Therapeut Res Inst Preparation of immunoglobulin with high content of monomer
JPS5821623A (ja) * 1981-07-28 1983-02-08 Tetsuzo Sugizaki 抗原抗体複合体沈着疾患治療剤
US4479895A (en) * 1982-05-05 1984-10-30 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4470925A (en) * 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
CA1194415A (en) * 1982-05-05 1985-10-01 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4465670A (en) * 1982-07-23 1984-08-14 Dainippon Pharmaceutical Co., Ltd. Method for the treatment of systemic lupus erythematosus and primary glomerulonephritis and agent therefor
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
JPH05506218A (ja) * 1990-05-07 1993-09-16 イムノメデイツクス・インコーポレイテツド 一価の抗体フラグメントの改良された放射性標識方法
NO346070B1 (no) * 2003-02-10 2022-01-31 Biogen Ma Inc Stabil, vandig, farmasøytisk formulering og fremgangsmåte for fremstilling derav.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3597409A (en) * 1970-05-25 1971-08-03 American Cyanamid Co Process for recoverring immunoglobulin a and immunoglobulin m

Also Published As

Publication number Publication date
DK141432C (enFirst) 1980-09-15
IN138636B (enFirst) 1976-03-06
GB1497928A (en) 1978-01-12
NO750768L (enFirst) 1975-09-09
DK93475A (enFirst) 1975-09-09
SE7502346L (sv) 1975-09-09
FR2262996B1 (enFirst) 1982-01-29
FR2262996A1 (enFirst) 1975-10-03
AU7872975A (en) 1976-09-09
DE2508132B2 (de) 1980-02-21
DE2508132C3 (de) 1980-10-16
SE403703B (sv) 1978-09-04
NL167167C (nl) 1981-11-16
DK141432B (da) 1980-03-17
DD118655A5 (enFirst) 1976-03-12
CH614426A5 (enFirst) 1979-11-30
NL167167B (nl) 1981-06-16
DE2508132A1 (de) 1975-09-11
NO144111B (no) 1981-03-16
US4059571A (en) 1977-11-22
NO144111C (no) 1981-06-24
NL7502745A (nl) 1975-09-10
DE2560155C2 (de) 1984-04-26

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