BRPI1014765A2 - microesferas de amplificação de sinal, seu uso em procedimento de amplificação analítica de uma etapa e multietapa e métodos para sua produção. - Google Patents
microesferas de amplificação de sinal, seu uso em procedimento de amplificação analítica de uma etapa e multietapa e métodos para sua produção.Info
- Publication number
- BRPI1014765A2 BRPI1014765A2 BRPI1014765A BRPI1014765A BRPI1014765A2 BR PI1014765 A2 BRPI1014765 A2 BR PI1014765A2 BR PI1014765 A BRPI1014765 A BR PI1014765A BR PI1014765 A BRPI1014765 A BR PI1014765A BR PI1014765 A2 BRPI1014765 A2 BR PI1014765A2
- Authority
- BR
- Brazil
- Prior art keywords
- multistep
- production
- methods
- amplification
- analytical
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0910010A GB2470939A (en) | 2009-06-10 | 2009-06-10 | Signal amplification microspheres |
PCT/GB2010/001144 WO2010142960A1 (en) | 2009-06-10 | 2010-06-10 | Signal amplification microspheres, their use in one-step and multi-step analytical amplification procedures and methods for their production |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1014765A2 true BRPI1014765A2 (pt) | 2016-04-19 |
Family
ID=40937206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1014765A BRPI1014765A2 (pt) | 2009-06-10 | 2010-06-10 | microesferas de amplificação de sinal, seu uso em procedimento de amplificação analítica de uma etapa e multietapa e métodos para sua produção. |
Country Status (12)
Country | Link |
---|---|
US (2) | US9151748B2 (pt) |
EP (1) | EP2440926B1 (pt) |
JP (1) | JP2012529644A (pt) |
KR (1) | KR20120027332A (pt) |
CN (1) | CN102803962B (pt) |
AU (1) | AU2010258403A1 (pt) |
BR (1) | BRPI1014765A2 (pt) |
CA (1) | CA2763852A1 (pt) |
ES (1) | ES2528970T3 (pt) |
GB (2) | GB2470939A (pt) |
TW (1) | TW201107752A (pt) |
WO (1) | WO2010142960A1 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8586387B2 (en) | 2011-08-30 | 2013-11-19 | Supernova Diagnostics, Inc. | Methods of triggering activation of encapsulated signal-generating substances and apparatus utilising activated signal-generating substances |
CN103769018B (zh) * | 2012-10-25 | 2016-10-26 | 上海市肿瘤研究所 | 改性凝集素包裹的磁性大分子脂质体微球、制备方法及应用 |
WO2015172232A1 (en) * | 2014-05-14 | 2015-11-19 | 1866402 Ontario Limited | Bonded microsphere filter |
US10048269B2 (en) | 2014-07-25 | 2018-08-14 | SeLux Diagnostics, Inc. | Assay methods involving dissociable nanoparticles |
CN105154521A (zh) * | 2015-05-14 | 2015-12-16 | 北京化工大学 | 一种新型氧化还原聚合辅助信号放大用于分子诊断的方法 |
CN104911222B (zh) * | 2015-06-24 | 2018-01-16 | 中国科学院广州能源研究所 | 一种离子液体体系下无载体固定化脂肪酶催化制备生物柴油的方法 |
WO2018026965A1 (en) * | 2016-08-02 | 2018-02-08 | Isi Life Sciences, Inc. | Compositions and methods for detecting cancer cells in a tissue sample |
KR101970327B1 (ko) * | 2017-04-13 | 2019-04-18 | 고려대학교 산학협력단 | 검출 신호의 자가 증폭 원리를 이용한 정확, 신속, 편리한 단일 단계 질병 진단 방법 |
WO2019246289A1 (en) * | 2018-06-22 | 2019-12-26 | Somalogic, Inc. | Improved proteomic multiplex assays |
CN116337851A (zh) * | 2018-07-18 | 2023-06-27 | 科美博阳诊断技术(上海)有限公司 | 一种均相化学发光检测试剂盒及其应用 |
CN109580731B (zh) * | 2019-01-15 | 2021-01-05 | 安徽师范大学 | Dna微囊及金电极-dna树枝状大分子传感器的制备方法以及在检测多氯联苯中的应用 |
CN110639442A (zh) * | 2019-10-09 | 2020-01-03 | 天津工业大学 | 一种负载双氯芬酸钠的天然多糖微胶囊的制备方法 |
CN112044371B (zh) * | 2020-09-07 | 2021-11-30 | 山东大学 | 一种制备单分散性海藻酸钙微球的装置、方法及应用 |
CN112578109B (zh) * | 2020-12-08 | 2022-10-11 | 广东海洋大学深圳研究院 | 定性定量检测试剂、制备方法及定性定量检测试剂盒 |
CN113588959A (zh) * | 2021-09-10 | 2021-11-02 | 河南农业大学 | 一种用于检测T-2毒素的turn-on型试纸条及其制备方法 |
CN114324857A (zh) * | 2021-12-31 | 2022-04-12 | 北京普赞生物技术有限公司 | 一种用于elisa试剂盒信号放大的微球及其制备方法 |
CN114324898B (zh) * | 2022-03-11 | 2022-05-31 | 南京岚煜生物科技有限公司 | 用于肝素结合蛋白hbp检测的结合垫处理液 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4703017C1 (en) | 1984-02-14 | 2001-12-04 | Becton Dickinson Co | Solid phase assay with visual readout |
CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
US4874710A (en) | 1986-02-20 | 1989-10-17 | Becton Dickinson And Company | Assay and product in which binder and liposomes are supported on a solid support |
DK112986D0 (da) * | 1986-03-11 | 1986-03-11 | Svenska Sockerfabriks Ab | Fremgangsmaade til detektion af komponenter i en proeve |
US5069936A (en) * | 1987-06-25 | 1991-12-03 | Yen Richard C K | Manufacturing protein microspheres |
US6013531A (en) | 1987-10-26 | 2000-01-11 | Dade International Inc. | Method to use fluorescent magnetic polymer particles as markers in an immunoassay |
SE8704158L (sv) * | 1987-10-26 | 1989-04-27 | Carbomatrix Ab C O Ulf Schroed | Mikrosfaerer, foerfarande foer framstaellning daerav och anvaendning daerav |
US5271961A (en) * | 1989-11-06 | 1993-12-21 | Alkermes Controlled Therapeutics, Inc. | Method for producing protein microspheres |
US5665383A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of immunostimulating agents for in vivo delivery |
US6238931B1 (en) | 1993-09-24 | 2001-05-29 | Biosite Diagnostics, Inc. | Fluorescence energy transfer in particles |
US5756362A (en) | 1993-10-12 | 1998-05-26 | Cornell Research Foundation, Inc. | Liposome-enhanced immunoaggregation assay and test device |
US5580749A (en) * | 1994-10-21 | 1996-12-03 | Georgia Tech Research Corporation | Internal reference for chemically modified spheres |
US5686113A (en) * | 1995-03-21 | 1997-11-11 | Temple University Of The Commonwealth System Of Higher Education | Microcapsules of predetermined peptide(s) specificity (ies), their preparation and uses |
DE19703718A1 (de) | 1996-01-23 | 1997-07-24 | Inst Chemo Biosensorik | Affinitätssensoren und -assays |
US5777098A (en) * | 1996-07-23 | 1998-07-07 | University Of North Dakota Medical Education Research Foundation | DNA purification procedure |
DE19852928C1 (de) * | 1998-11-17 | 2000-08-03 | Steffen Panzner | Strukturen in Form von Hohlkugeln |
AU4304901A (en) * | 1999-11-15 | 2001-06-04 | Biocure, Inc. | Responsive polymeric hollow particles |
DE10042023C2 (de) * | 2000-08-08 | 2003-04-10 | Biognostic Ag | Kapseln, die feste Teilchen signalerzeugender Substanzen einkapseln, und deren Verwendung bei Bioassays zum Nachweis von Zielmolekülen in einer Probe |
US20030138975A1 (en) * | 2001-12-20 | 2003-07-24 | Kimberly-Clark Worldwide, Inc. | Diagnostic signal amplification with proteinoid microspheres |
EP1488006B1 (en) | 2002-03-20 | 2008-05-28 | InnovativeBio.Biz | Microcapsules with controlable permeability encapsulating a nucleic acid amplification reaction mixture and their use as reaction compartments for parallels reactions |
AU2003251428A1 (en) * | 2002-06-10 | 2003-12-22 | The Government Of The United States, As Represented By The Secretary Of The Department Of Health And | Novel molecular conjugates for signal amplification |
CN1476897A (zh) * | 2002-08-21 | 2004-02-25 | 中国科学院大连化学物理研究所 | 一种小粒径的蛋白质药物微球载体制备技术 |
US7348399B2 (en) * | 2003-08-29 | 2008-03-25 | Louisiana Tech University Foundation, Inc. | Nanofabricated polypeptide multilayer films, coatings, and microcapsules |
WO2005062982A2 (en) * | 2003-12-23 | 2005-07-14 | Xing-Xiang Li | Signal amplification methods for analyte detection |
MX2008006180A (es) * | 2005-11-14 | 2008-09-22 | Louisiana Tech University Res | Peliculas de polipeptido y metodos. |
US20090304599A1 (en) * | 2005-12-20 | 2009-12-10 | Fujifilm Corporation | Protein Nanoparticles and the Use of the Same |
JP4974533B2 (ja) * | 2006-01-30 | 2012-07-11 | 富士フイルム株式会社 | ジスルフィド架橋したタンパク質ナノ粒子 |
US20090104275A1 (en) * | 2006-11-23 | 2009-04-23 | Alexander Grinberg | Nanoencapsulation of Proteins |
EP2014280B1 (en) * | 2007-07-13 | 2014-10-08 | CC-Ery GmbH | Micro-particles, blood-substitute and method for forming same |
-
2009
- 2009-06-10 GB GB0910010A patent/GB2470939A/en not_active Withdrawn
-
2010
- 2010-06-10 TW TW099118868A patent/TW201107752A/zh unknown
- 2010-06-10 BR BRPI1014765A patent/BRPI1014765A2/pt not_active Application Discontinuation
- 2010-06-10 US US13/375,108 patent/US9151748B2/en not_active Expired - Fee Related
- 2010-06-10 KR KR1020117029621A patent/KR20120027332A/ko not_active Application Discontinuation
- 2010-06-10 CN CN201080026352.4A patent/CN102803962B/zh not_active Expired - Fee Related
- 2010-06-10 JP JP2012514531A patent/JP2012529644A/ja not_active Withdrawn
- 2010-06-10 CA CA2763852A patent/CA2763852A1/en not_active Abandoned
- 2010-06-10 AU AU2010258403A patent/AU2010258403A1/en not_active Abandoned
- 2010-06-10 WO PCT/GB2010/001144 patent/WO2010142960A1/en active Application Filing
- 2010-06-10 EP EP10731777.8A patent/EP2440926B1/en not_active Not-in-force
- 2010-06-10 GB GB1120657.0A patent/GB2483393A/en not_active Withdrawn
- 2010-06-10 ES ES10731777.8T patent/ES2528970T3/es active Active
-
2015
- 2015-08-27 US US14/837,501 patent/US10048257B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR20120027332A (ko) | 2012-03-21 |
CN102803962B (zh) | 2015-06-24 |
ES2528970T3 (es) | 2015-02-13 |
US9151748B2 (en) | 2015-10-06 |
AU2010258403A1 (en) | 2011-12-15 |
CA2763852A1 (en) | 2010-12-16 |
US10048257B2 (en) | 2018-08-14 |
JP2012529644A (ja) | 2012-11-22 |
GB2483393A (en) | 2012-03-07 |
US20160047802A1 (en) | 2016-02-18 |
WO2010142960A1 (en) | 2010-12-16 |
GB0910010D0 (en) | 2009-07-22 |
EP2440926A1 (en) | 2012-04-18 |
EP2440926B1 (en) | 2014-12-10 |
TW201107752A (en) | 2011-03-01 |
GB2470939A (en) | 2010-12-15 |
CN102803962A (zh) | 2012-11-28 |
US20120171747A1 (en) | 2012-07-05 |
GB201120657D0 (en) | 2012-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |