BRPI1011515A2 - derivados de pirrolo[2,3-b] piridina para a inibição de raf cinases - Google Patents
derivados de pirrolo[2,3-b] piridina para a inibição de raf cinasesInfo
- Publication number
- BRPI1011515A2 BRPI1011515A2 BRPI1011515A BRPI1011515A BRPI1011515A2 BR PI1011515 A2 BRPI1011515 A2 BR PI1011515A2 BR PI1011515 A BRPI1011515 A BR PI1011515A BR PI1011515 A BRPI1011515 A BR PI1011515A BR PI1011515 A2 BRPI1011515 A2 BR PI1011515A2
- Authority
- BR
- Brazil
- Prior art keywords
- pyrrolo
- inhibition
- pyridine derivatives
- raf kinases
- raf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15939009P | 2009-03-11 | 2009-03-11 | |
| US15940609P | 2009-03-11 | 2009-03-11 | |
| US15939609P | 2009-03-11 | 2009-03-11 | |
| US15940209P | 2009-03-11 | 2009-03-11 | |
| US15939209P | 2009-03-11 | 2009-03-11 | |
| US15939509P | 2009-03-11 | 2009-03-11 | |
| US15940009P | 2009-03-11 | 2009-03-11 | |
| PCT/US2010/026816 WO2010104945A1 (en) | 2009-03-11 | 2010-03-10 | Pyrrolo [2, 3-b] pyridine derivatives for the inhibition of raf kinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1011515A2 true BRPI1011515A2 (pt) | 2016-03-29 |
Family
ID=42199540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1011515A BRPI1011515A2 (pt) | 2009-03-11 | 2010-03-10 | derivados de pirrolo[2,3-b] piridina para a inibição de raf cinases |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8901301B2 (pt) |
| EP (1) | EP2406259A1 (pt) |
| JP (1) | JP2012520307A (pt) |
| KR (1) | KR101663339B1 (pt) |
| CN (1) | CN102421776A (pt) |
| AR (1) | AR075812A1 (pt) |
| AU (1) | AU2010224245B2 (pt) |
| BR (1) | BRPI1011515A2 (pt) |
| CA (1) | CA2755045A1 (pt) |
| CO (1) | CO6620074A2 (pt) |
| CR (1) | CR20110476A (pt) |
| EC (1) | ECSP11011313A (pt) |
| MA (1) | MA33181B1 (pt) |
| MX (1) | MX2011009489A (pt) |
| MY (1) | MY161861A (pt) |
| NI (1) | NI201100168A (pt) |
| NO (1) | NO20111241A1 (pt) |
| PE (1) | PE20120184A1 (pt) |
| RU (1) | RU2011141123A (pt) |
| SG (2) | SG10201402977WA (pt) |
| TW (1) | TW201036973A (pt) |
| WO (1) | WO2010104945A1 (pt) |
| ZA (1) | ZA201106599B (pt) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| EP2170830B1 (en) | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
| US8158636B2 (en) | 2008-05-19 | 2012-04-17 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| JP2012509342A (ja) | 2008-11-20 | 2012-04-19 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | 置換ピロロ［２，３−ｂ］−ピリジンおよび−ピラジン |
| MY172424A (en) | 2009-04-03 | 2019-11-25 | Hoffmann La Roche | Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof |
| BR112012012156A2 (pt) | 2009-11-06 | 2015-09-08 | Plexxikon Inc | compostos e métodos para modulação de cinase, e indicações para esta |
| ES2627911T3 (es) | 2009-11-18 | 2017-08-01 | Plexxikon, Inc. | Derivados de N-[2-fluoro-3-(4-amino-7H-pirrolo[2,3-d]pirimidin-5-carbonil)-fenil]-4-bencenosulfonamida como moduladores de la proteína quinasa Raf para el tratamiento del cáncer |
| AU2010336524B2 (en) * | 2009-12-23 | 2015-10-08 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
| TWI619713B (zh) | 2010-04-21 | 2018-04-01 | 普雷辛肯公司 | 用於激酶調節的化合物和方法及其適應症 |
| AR081039A1 (es) | 2010-05-14 | 2012-05-30 | Osi Pharmaceuticals Llc | Inhibidores biciclicos fusionados de quinasa |
| US20130072495A1 (en) | 2010-05-14 | 2013-03-21 | OSI Pharmaceuticals, LLC | Fused bicyclic kinase inhibitors |
| US8771687B2 (en) | 2010-12-02 | 2014-07-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods for treating a tumor using an antibody that specifically binds GRP94 |
| TR201816421T4 (tr) | 2011-02-07 | 2018-11-21 | Plexxikon Inc | Kinaz modülasyonu için bileşikler ve metotlar ve bunların endikasyonları. |
| WO2012149547A1 (en) * | 2011-04-28 | 2012-11-01 | Duke University | Methods of treating hemoglobinopathies |
| AU2012255275B2 (en) | 2011-05-17 | 2016-01-28 | Plexxikon Inc. | Kinase modulation and indications therefor |
| US9988687B2 (en) * | 2011-09-20 | 2018-06-05 | The George Washington Univeristy | Companion diagnostics for cancer and screening methods to identify companion diagnostics for cancer based on splicing variants |
| WO2013043935A1 (en) | 2011-09-21 | 2013-03-28 | Neupharma, Inc. | Certain chemical entites, compositions, and methods |
| US20130172375A1 (en) | 2011-12-13 | 2013-07-04 | Hoffmann-La Roche Inc. | Pharmaceutical composition |
| US9358235B2 (en) | 2012-03-19 | 2016-06-07 | Plexxikon Inc. | Kinase modulation, and indications therefor |
| US9150570B2 (en) * | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| AU2013280644B2 (en) | 2012-06-26 | 2018-08-02 | Jeffrey A. BACHA | Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof |
| TWI601725B (zh) | 2012-08-27 | 2017-10-11 | 加拓科學公司 | 取代的氮雜吲哚化合物及其鹽、組合物和用途 |
| US10227357B2 (en) | 2012-09-06 | 2019-03-12 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| WO2014081760A1 (en) | 2012-11-20 | 2014-05-30 | Duke University | Methods of treating hemoglobinopathies |
| KR102212923B1 (ko) | 2012-12-21 | 2021-02-04 | 플렉시콘 인코퍼레이티드 | 키나제 조절을 위한 화합물 및 방법, 및 그에 대한 적응증 |
| US20140303121A1 (en) | 2013-03-15 | 2014-10-09 | Plexxikon Inc. | Heterocyclic compounds and uses thereof |
| KR102244719B1 (ko) | 2013-03-15 | 2021-04-26 | 플렉시콘 인코퍼레이티드 | 헤테로시클릭 화합물 및 그의 용도 |
| JP2016519684A (ja) | 2013-04-08 | 2016-07-07 | デニス エム ブラウン | 準最適に投与された薬物療法の有効性を改善するための及び／又は副作用を低減するための方法および組成物 |
| SG11201509338QA (en) * | 2013-05-30 | 2015-12-30 | Plexxikon Inc | Compounds for kinase modulation, and indications therefor |
| US9771369B2 (en) | 2014-03-04 | 2017-09-26 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| EP3194392B1 (en) | 2014-09-15 | 2020-01-01 | Plexxikon, Inc. | Heterocyclic compounds and uses thereof |
| WO2016057367A1 (en) | 2014-10-06 | 2016-04-14 | Dana-Farber Cancer Institute, Inc. | Angiopoietin-2 biomarkers predictive of anti-immune checkpoint response |
| US10160755B2 (en) | 2015-04-08 | 2018-12-25 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| HUE047657T2 (hu) | 2015-05-06 | 2020-05-28 | Plexxikon Inc | Kináz-moduláló hatású 1H-pirrolo[2,3-b]piridin származékok szintézise |
| US9802932B2 (en) | 2015-05-06 | 2017-10-31 | Plexxikon Inc. | Solid forms of a compound modulating kinases |
| WO2017019804A2 (en) | 2015-07-28 | 2017-02-02 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| KR20180052757A (ko) | 2015-09-21 | 2018-05-18 | 플렉시콘 인코퍼레이티드 | 헤테로시클릭 화합물 및 그의 용도 |
| US9938273B2 (en) | 2015-12-07 | 2018-04-10 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| EP3430005B1 (en) | 2016-03-16 | 2021-12-08 | Plexxikon Inc. | Compounds and methods for kinase modulation and indications therefore |
| TW201815766A (zh) | 2016-09-22 | 2018-05-01 | 美商普雷辛肯公司 | 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症 |
| CA3047580A1 (en) | 2016-12-23 | 2018-07-26 | Plexxikon Inc. | Compounds and methods for cdk8 modulation and indications therefor |
| NZ755835A (en) | 2017-01-17 | 2023-12-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| US10577366B2 (en) | 2017-03-20 | 2020-03-03 | Plexxikon Inc. | Crystalline forms of a compound that inhibits bromodomain |
| US10428067B2 (en) | 2017-06-07 | 2019-10-01 | Plexxikon Inc. | Compounds and methods for kinase modulation |
| US10435404B2 (en) | 2017-07-25 | 2019-10-08 | Plexxikon Inc. | Formulations of a compound modulating kinases |
| WO2019075243A1 (en) | 2017-10-13 | 2019-04-18 | Plexxikon Inc. | SOLID FORMS OF A COMPOUND FOR MODULATING KINASES |
| CA3080197C (en) | 2017-10-27 | 2023-12-19 | Plexxikon Inc. | Formulations of a compound modulating kinases |
| WO2019149738A1 (en) | 2018-01-31 | 2019-08-08 | Heparegenix Gmbh | Protein kinase mkk4 inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| CN112119072A (zh) | 2018-03-20 | 2020-12-22 | 普莱希科公司 | 用于ido和tdo调节的化合物和方法，以及其适应症 |
| GB201809460D0 (en) * | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
| EP3810139A1 (en) | 2018-06-21 | 2021-04-28 | HepaRegeniX GmbH | Tricyclic protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| AU2019303986B2 (en) | 2018-07-16 | 2024-02-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| EP3953351A1 (en) | 2019-04-09 | 2022-02-16 | Plexxikon Inc. | Condensed azines for ep300 or cbp modulation and indications therefor |
| EP4139296A1 (en) | 2020-04-23 | 2023-03-01 | Opna Immuno Oncology, SA | Compounds and methods for cd73 modulation and indications therefor |
| WO2022040512A1 (en) | 2020-08-21 | 2022-02-24 | Plexxikon Inc. | Combinational drug anticancer therapies |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101476067B1 (ko) | 2002-09-06 | 2014-12-23 | 인설트 테라페틱스, 인코퍼레이티드 | 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체 |
| BRPI0611863B1 (pt) * | 2005-06-22 | 2021-11-23 | Plexxikon, Inc | Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo |
| PE20121126A1 (es) * | 2006-12-21 | 2012-08-24 | Plexxikon Inc | Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa |
-
2010
- 2010-03-10 CN CN2010800206771A patent/CN102421776A/zh active Pending
- 2010-03-10 CA CA2755045A patent/CA2755045A1/en not_active Abandoned
- 2010-03-10 PE PE2011001620A patent/PE20120184A1/es not_active Application Discontinuation
- 2010-03-10 MA MA34228A patent/MA33181B1/fr unknown
- 2010-03-10 RU RU2011141123/04A patent/RU2011141123A/ru unknown
- 2010-03-10 WO PCT/US2010/026816 patent/WO2010104945A1/en active Application Filing
- 2010-03-10 SG SG10201402977WA patent/SG10201402977WA/en unknown
- 2010-03-10 JP JP2011554147A patent/JP2012520307A/ja not_active Withdrawn
- 2010-03-10 US US12/721,496 patent/US8901301B2/en active Active
- 2010-03-10 KR KR1020117023712A patent/KR101663339B1/ko active IP Right Grant
- 2010-03-10 BR BRPI1011515A patent/BRPI1011515A2/pt not_active Application Discontinuation
- 2010-03-10 MX MX2011009489A patent/MX2011009489A/es not_active Application Discontinuation
- 2010-03-10 AR ARP100100731A patent/AR075812A1/es unknown
- 2010-03-10 EP EP10708681A patent/EP2406259A1/en not_active Withdrawn
- 2010-03-10 AU AU2010224245A patent/AU2010224245B2/en active Active
- 2010-03-10 MY MYPI2011004233A patent/MY161861A/en unknown
- 2010-03-10 TW TW099106990A patent/TW201036973A/zh unknown
- 2010-03-10 SG SG2011063914A patent/SG174257A1/en unknown
-
2011
- 2011-08-09 EC EC2011011313A patent/ECSP11011313A/es unknown
- 2011-09-06 CR CR20110476A patent/CR20110476A/es unknown
- 2011-09-08 ZA ZA2011/06599A patent/ZA201106599B/en unknown
- 2011-09-09 NI NI201100168A patent/NI201100168A/es unknown
- 2011-09-12 CO CO11117856A patent/CO6620074A2/es not_active Application Discontinuation
- 2011-09-13 NO NO20111241A patent/NO20111241A1/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SG174257A1 (en) | 2011-10-28 |
| MA33181B1 (fr) | 2012-04-02 |
| TW201036973A (en) | 2010-10-16 |
| US8901301B2 (en) | 2014-12-02 |
| ECSP11011313A (es) | 2011-10-31 |
| PE20120184A1 (es) | 2012-03-28 |
| EP2406259A1 (en) | 2012-01-18 |
| MY161861A (en) | 2017-05-15 |
| JP2012520307A (ja) | 2012-09-06 |
| MX2011009489A (es) | 2011-10-11 |
| SG10201402977WA (en) | 2014-09-26 |
| AU2010224245A1 (en) | 2011-09-29 |
| NO20111241A1 (no) | 2011-09-28 |
| CR20110476A (es) | 2012-01-04 |
| RU2011141123A (ru) | 2013-04-20 |
| AR075812A1 (es) | 2011-04-27 |
| WO2010104945A1 (en) | 2010-09-16 |
| CO6620074A2 (es) | 2013-02-15 |
| ZA201106599B (en) | 2014-02-26 |
| US20100286178A1 (en) | 2010-11-11 |
| CA2755045A1 (en) | 2010-09-16 |
| NI201100168A (es) | 2012-01-11 |
| CN102421776A (zh) | 2012-04-18 |
| KR20110125670A (ko) | 2011-11-21 |
| KR101663339B1 (ko) | 2016-10-06 |
| AU2010224245B2 (en) | 2016-07-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI1011515A2 (pt) | derivados de pirrolo[2,3-b] piridina para a inibição de raf cinases | |
| HRP20171724T1 (hr) | Imidazo[1,2-b]piridazin derivati kao inhibitori kinaze | |
| AP2939A (en) | Thieno [2,3-B] pyridine derivatives as viral replication inhibitors | |
| BR112012002110A2 (pt) | derivados de pirrolo[1,2-b]piridazina como inibidores de janus cinase | |
| EP2205611A4 (en) | PROCESS FOR THE PRODUCTION OF PRASUGREL AND SALTS AND POLYMERS THEREOF | |
| BRPI0722088A2 (pt) | derivados de pirrolo[2,3-b]piridina como moduladores de cinase | |
| ZA201108124B (en) | Pyrrolo [2,3-b] pyridines which inhibit raf protein kinase | |
| BRPI0919948A2 (pt) | Pirido[4,3-b]indois contendo porções rígidas | |
| IL210172A0 (en) | Substituted pyrimidin-4-one derivatives | |
| GB0702259D0 (en) | 7-azaindole derivatives | |
| ZA201108885B (en) | 3-([1,2,3]triazole-4yl)-pyrrolo[2,3-b]pyridine derivates | |
| DK2124944T3 (da) | Pyrazolo[3,4-b]pyridinderivater som phosphodiesteraseinhibitorer | |
| BRPI1008850A2 (pt) | [1,2,4]triazolo[1,5-a]piridinas como inibidores de quinase | |
| IL211241A0 (en) | 7-azaindole derivatives | |
| ZA201009272B (en) | Substituted alkyl pyrimidin-4-one derivatives | |
| ZA201100437B (en) | 3-(3-pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazine derivatives as met kinase inhibitors | |
| IL232717A0 (en) | 3-cyanoaryl-h1-pyrrolo[b-3,2]pyridine derivatives | |
| PL2155679T3 (pl) | Sposób wytwarzania pochodnych 4-formyloaminopiperydyny | |
| GB0702265D0 (en) | 7-Azaindole derivatives | |
| EP2565194A4 (en) | Imidazo [1,2-A] pyridine | |
| EP2490693A4 (en) | Pyrazolo [3,4-B] PYRIDINE-4-ON-KINASE INHIBITORS | |
| IL214957A0 (en) | Pyrrolo [2,3-b] pyridine derivatives for the inhibition of raf kinases | |
| GB0702260D0 (en) | 7-azaindole derivatives | |
| BRPI0906985A2 (pt) | Derivados de pirido[4,3-d]pirimidinona como inibidores de cinase |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A ANUIDADE. |
|
| B08G | Application fees: restoration | ||
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A ANUIDADE. |
|
| B08H | Application fees: decision cancelled | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B07E | Notice of approval relating to section 229 industrial property law |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |