BRPI1007476A2 - análogos de ciclosporina para prevenir ou tratar infecção por hepatite c - Google Patents
análogos de ciclosporina para prevenir ou tratar infecção por hepatite cInfo
- Publication number
- BRPI1007476A2 BRPI1007476A2 BRPI1007476A BRPI1007476A BRPI1007476A2 BR PI1007476 A2 BRPI1007476 A2 BR PI1007476A2 BR PI1007476 A BRPI1007476 A BR PI1007476A BR PI1007476 A BRPI1007476 A BR PI1007476A BR PI1007476 A2 BRPI1007476 A2 BR PI1007476A2
- Authority
- BR
- Brazil
- Prior art keywords
- infection
- prevent
- treat hepatitis
- cyclosporine analogues
- cyclosporine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14858309P | 2009-01-30 | 2009-01-30 | |
PCT/US2010/022675 WO2010088573A1 (en) | 2009-01-30 | 2010-01-30 | Cyclosporin analogues for preventing or treating hepatitis c infection |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1007476A2 true BRPI1007476A2 (pt) | 2016-02-16 |
Family
ID=42396050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1007476A BRPI1007476A2 (pt) | 2009-01-30 | 2010-01-30 | análogos de ciclosporina para prevenir ou tratar infecção por hepatite c |
Country Status (14)
Country | Link |
---|---|
US (3) | US8367618B2 (pt) |
EP (1) | EP2391376A4 (pt) |
JP (1) | JP5406943B2 (pt) |
KR (2) | KR101476626B1 (pt) |
CN (1) | CN102365094A (pt) |
AU (1) | AU2010208071C1 (pt) |
BR (1) | BRPI1007476A2 (pt) |
CA (1) | CA2751210C (pt) |
IL (1) | IL214278A0 (pt) |
MX (1) | MX2011008000A (pt) |
NZ (1) | NZ594755A (pt) |
RU (1) | RU2492181C2 (pt) |
SG (1) | SG173180A1 (pt) |
WO (1) | WO2010088573A1 (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI1007476A2 (pt) * | 2009-01-30 | 2016-02-16 | Enanta Pharm Inc | análogos de ciclosporina para prevenir ou tratar infecção por hepatite c |
US8481483B2 (en) * | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8367053B2 (en) * | 2009-07-09 | 2013-02-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8685917B2 (en) * | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8349312B2 (en) * | 2009-07-09 | 2013-01-08 | Enanta Pharmaceuticals, Inc. | Proline substituted cyclosporin analogues |
AU2010339460A1 (en) * | 2009-12-30 | 2012-07-19 | Scynexis Inc. | Cyclosporine analogues |
US8623814B2 (en) * | 2010-02-23 | 2014-01-07 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
CN103153329A (zh) | 2010-07-16 | 2013-06-12 | 美国科技环球有限公司 | 新颖的环孢霉素a衍生物在病毒感染的治疗和预防中的应用 |
US9573978B2 (en) * | 2010-08-12 | 2017-02-21 | S&T Global, Inc. | Cyclosporin derivatives for the treatment and prevention of a viral infection |
US9890198B2 (en) * | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
WO2012075494A1 (en) * | 2010-12-03 | 2012-06-07 | S&T Global Inc. | Novel cyclosporin derivatives for the treatment and prevention of a viral infection |
MY192981A (en) | 2010-12-15 | 2022-09-20 | Contravir Pharmaceuticals Inc | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
US9428845B1 (en) | 2010-12-28 | 2016-08-30 | Warp Drive Bio, Inc. | Identifying new therapeutic agents |
AR090964A1 (es) * | 2012-05-09 | 2014-12-17 | Novartis Ag | Proceso para la elaboracion de undecapeptidos ciclicos |
EP2855508B1 (en) | 2012-06-01 | 2018-02-14 | Allergan, Inc. | Cyclosporin a analogs |
JP2015532277A (ja) | 2012-09-29 | 2015-11-09 | ノバルティス アーゲー | 環状ペプチドおよび医薬としてのその使用 |
US8906853B2 (en) | 2012-11-28 | 2014-12-09 | Enanta Pharmaceuticals, Inc. | [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection |
CA2921961A1 (en) * | 2013-08-26 | 2015-03-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis c |
JP6413455B2 (ja) * | 2014-08-07 | 2018-10-31 | 日本電気株式会社 | 給湯機制御装置、給湯機制御システム、給湯機制御方法およびプログラム |
GB201414806D0 (en) | 2014-08-20 | 2014-10-01 | Ucl Business Plc | Cyclosporin conjugates |
US9669095B2 (en) | 2014-11-03 | 2017-06-06 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis C infection |
CN105693820A (zh) * | 2014-11-27 | 2016-06-22 | 武汉药明康德新药开发有限公司 | 一种降解环孢菌素a的方法 |
TW201639873A (zh) | 2015-01-08 | 2016-11-16 | 歐樂根公司 | Mebmt側鏈已環化之環孢菌素衍生物 |
TW201629069A (zh) | 2015-01-09 | 2016-08-16 | 霍普驅動生物科技股份有限公司 | 參與協同結合之化合物及其用途 |
WO2016112295A1 (en) | 2015-01-09 | 2016-07-14 | Warp Drive Bio, Inc. | Compounds that participate in cooperative binding and uses thereof |
EP3355930A4 (en) | 2015-10-01 | 2019-03-06 | Warp Drive Bio, Inc. | METHOD AND REAGENTS FOR THE ANALYSIS OF PROTEIN-PROTEIN INTERFACES |
MA44680A (fr) | 2016-04-12 | 2019-02-20 | Warp Drive Bio Inc | Compositions et procédés pour la production de composés |
KR20190099396A (ko) | 2016-10-28 | 2019-08-27 | 징코 바이오웍스, 인크. | 화합물의 생산을 위한 조성물 및 방법 |
JP2022553858A (ja) | 2019-11-04 | 2022-12-26 | レボリューション メディシンズ インコーポレイテッド | Ras阻害剤 |
TW202132314A (zh) | 2019-11-04 | 2021-09-01 | 美商銳新醫藥公司 | Ras抑制劑 |
CR20220240A (es) | 2019-11-04 | 2022-08-03 | Revolution Medicines Inc | Inhibidores de ras |
IL301298A (en) | 2020-09-15 | 2023-05-01 | Revolution Medicines Inc | Indole derivatives as RAS inhibitors in cancer therapy |
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CH614931A5 (pt) * | 1975-11-04 | 1979-12-28 | Sandoz Ag | |
DE2819094A1 (de) * | 1977-05-10 | 1978-11-23 | Sandoz Ag | Cyclosporin-derivate, ihre verwendung und herstellung |
SE448386B (sv) * | 1978-10-18 | 1987-02-16 | Sandoz Ag | Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem |
EP0098456B1 (en) | 1980-02-14 | 1989-05-24 | Sandoz Ag | Peptides comprising a (1s,2r,3r)- or (1r,2s,3s)-1-nitrilo-1-carbonyl-3-methyl-2-oxy-heptane or -hept-5-ene residue useful in the total synthesis of cyclosporins, and processes for their production |
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DE3260468D1 (en) | 1981-01-09 | 1984-09-06 | Sandoz Ag | Novel cyclosporins |
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EP0194972B1 (en) * | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
US5239057A (en) * | 1987-03-27 | 1993-08-24 | Abbott Laboratories | Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies |
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GB2207678A (en) | 1987-08-03 | 1989-02-08 | Merck & Co Inc | Novel immunosuppressive fluorinated cyclosporin analogs |
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DE602005026294D1 (de) | 2004-07-14 | 2011-03-24 | Novartis Ag | Verwendung einer kombination von cyclosporin und pegylierten interferonen zur behandlung von hepatitis c (hcv) |
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CA2583494C (en) * | 2004-10-01 | 2014-01-21 | Scynexis, Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection |
CN101316859A (zh) | 2005-09-30 | 2008-12-03 | 西尼克斯公司 | 用于治疗和预防病毒感染的环孢菌素a的芳基烷基和杂芳基烷基衍生物 |
BRPI0617781A2 (pt) | 2005-10-26 | 2011-08-09 | Astellas Pharma Inc | compostos de peptìdeos cìclicos |
WO2007103550A2 (en) * | 2006-03-08 | 2007-09-13 | Achillion Pharmaceuticals, Inc. | Substituted aminothiazole derivatives with anti-hcv activity |
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US7776832B2 (en) * | 2006-04-21 | 2010-08-17 | Gem Pharmaceuticals, Llc | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
WO2008139986A1 (en) | 2007-05-02 | 2008-11-20 | Astellas Pharma Inc., | New cyclic peptide compounds |
WO2008143996A1 (en) * | 2007-05-18 | 2008-11-27 | Scynexis, Inc. | New chemical processes |
BRPI1007476A2 (pt) * | 2009-01-30 | 2016-02-16 | Enanta Pharm Inc | análogos de ciclosporina para prevenir ou tratar infecção por hepatite c |
US8481483B2 (en) | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8685917B2 (en) * | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8367053B2 (en) | 2009-07-09 | 2013-02-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
US8349312B2 (en) * | 2009-07-09 | 2013-01-08 | Enanta Pharmaceuticals, Inc. | Proline substituted cyclosporin analogues |
US8429835B2 (en) * | 2009-10-21 | 2013-04-30 | Nike, Inc. | Composite shoe upper and method of making same |
US8178531B2 (en) * | 2010-02-23 | 2012-05-15 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
US8623814B2 (en) * | 2010-02-23 | 2014-01-07 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
CN103153329A (zh) | 2010-07-16 | 2013-06-12 | 美国科技环球有限公司 | 新颖的环孢霉素a衍生物在病毒感染的治疗和预防中的应用 |
US9573978B2 (en) | 2010-08-12 | 2017-02-21 | S&T Global, Inc. | Cyclosporin derivatives for the treatment and prevention of a viral infection |
CA2921961A1 (en) * | 2013-08-26 | 2015-03-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis c |
-
2010
- 2010-01-30 BR BRPI1007476A patent/BRPI1007476A2/pt not_active Application Discontinuation
- 2010-01-30 CA CA2751210A patent/CA2751210C/en not_active Expired - Fee Related
- 2010-01-30 KR KR1020147001832A patent/KR101476626B1/ko not_active IP Right Cessation
- 2010-01-30 SG SG2011054715A patent/SG173180A1/en unknown
- 2010-01-30 JP JP2011548361A patent/JP5406943B2/ja not_active Expired - Fee Related
- 2010-01-30 EP EP10736507A patent/EP2391376A4/en not_active Withdrawn
- 2010-01-30 WO PCT/US2010/022675 patent/WO2010088573A1/en active Application Filing
- 2010-01-30 RU RU2011133900/04A patent/RU2492181C2/ru not_active IP Right Cessation
- 2010-01-30 US US12/697,215 patent/US8367618B2/en active Active
- 2010-01-30 MX MX2011008000A patent/MX2011008000A/es active IP Right Grant
- 2010-01-30 KR KR1020117020221A patent/KR20110111321A/ko not_active Application Discontinuation
- 2010-01-30 CN CN2010800142248A patent/CN102365094A/zh active Pending
- 2010-01-30 NZ NZ594755A patent/NZ594755A/en not_active IP Right Cessation
- 2010-01-30 AU AU2010208071A patent/AU2010208071C1/en not_active Ceased
-
2011
- 2011-07-25 IL IL214278A patent/IL214278A0/en unknown
-
2013
- 2013-01-04 US US13/734,074 patent/US9156886B2/en active Active
-
2015
- 2015-09-02 US US14/843,119 patent/US9603895B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
RU2011133900A (ru) | 2013-03-10 |
EP2391376A1 (en) | 2011-12-07 |
US9603895B2 (en) | 2017-03-28 |
JP2012516850A (ja) | 2012-07-26 |
CN102365094A (zh) | 2012-02-29 |
US20100196316A1 (en) | 2010-08-05 |
SG173180A1 (en) | 2011-09-29 |
NZ594755A (en) | 2013-12-20 |
US8367618B2 (en) | 2013-02-05 |
AU2010208071B2 (en) | 2012-11-08 |
MX2011008000A (es) | 2011-09-15 |
US9156886B2 (en) | 2015-10-13 |
AU2010208071A1 (en) | 2011-09-01 |
IL214278A0 (en) | 2011-09-27 |
AU2010208071C1 (en) | 2013-06-20 |
KR101476626B1 (ko) | 2014-12-26 |
RU2492181C2 (ru) | 2013-09-10 |
KR20110111321A (ko) | 2011-10-10 |
EP2391376A4 (en) | 2012-08-01 |
US20160051625A1 (en) | 2016-02-25 |
WO2010088573A1 (en) | 2010-08-05 |
CA2751210A1 (en) | 2010-08-05 |
CA2751210C (en) | 2015-04-21 |
KR20140014323A (ko) | 2014-02-05 |
JP5406943B2 (ja) | 2014-02-05 |
US20130183267A1 (en) | 2013-07-18 |
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