BR112012004676A2 - método de tratar infecções orotomixovirais. - Google Patents
método de tratar infecções orotomixovirais.Info
- Publication number
- BR112012004676A2 BR112012004676A2 BR112012004676A BR112012004676A BR112012004676A2 BR 112012004676 A2 BR112012004676 A2 BR 112012004676A2 BR 112012004676 A BR112012004676 A BR 112012004676A BR 112012004676 A BR112012004676 A BR 112012004676A BR 112012004676 A2 BR112012004676 A2 BR 112012004676A2
- Authority
- BR
- Brazil
- Prior art keywords
- orotomixoviral
- infections
- treating
- treating orotomixoviral
- orotomixoviral infections
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27225409P | 2009-09-04 | 2009-09-04 | |
| US28250810P | 2010-02-22 | 2010-02-22 | |
| US35393510P | 2010-06-11 | 2010-06-11 | |
| PCT/US2010/047488 WO2011028775A1 (en) | 2009-09-04 | 2010-09-01 | Methods of treating orthomyxoviral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012004676A2 true BR112012004676A2 (pt) | 2019-09-24 |
Family
ID=43649616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012004676A BR112012004676A2 (pt) | 2009-09-04 | 2010-09-01 | método de tratar infecções orotomixovirais. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20110065752A1 (pt) |
| EP (1) | EP2473482B1 (pt) |
| JP (1) | JP5653438B2 (pt) |
| KR (1) | KR101497194B1 (pt) |
| CN (1) | CN102625796B (pt) |
| BR (1) | BR112012004676A2 (pt) |
| CA (1) | CA2772875A1 (pt) |
| DK (1) | DK2473482T3 (pt) |
| ES (1) | ES2466027T3 (pt) |
| MX (1) | MX2012002486A (pt) |
| PL (1) | PL2473482T3 (pt) |
| WO (1) | WO2011028775A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102655746B (zh) | 2009-02-23 | 2016-08-03 | 联合治疗公司 | 亚氨基糖以及治疗病毒性疾病的方法 |
| US8921568B2 (en) | 2012-06-06 | 2014-12-30 | Unither Virology, Llc | Iminosugars and their applications |
| CA2924026C (en) | 2013-09-16 | 2021-12-28 | Emergent Virology Llc | Deoxynojirimycin derivatives and methods of their using |
| CA2966893C (en) | 2014-11-05 | 2023-10-24 | Emergent Virology Llc | Iminosugars |
| WO2017201030A1 (en) * | 2016-05-16 | 2017-11-23 | Emergent Virology Llc | Methods of treating viral infection |
| EP3934688A4 (en) * | 2019-03-08 | 2022-12-21 | University of Virginia Patent Foundation | COMPOSITIONS AND METHODS FOR MODULATION OF VIRAL INFECTION THROUGH REGULATION OF GLUCOSYLCERAMIDS |
| CN111904959A (zh) * | 2020-08-21 | 2020-11-10 | 牡丹江医学院 | α-L-岩藻糖苷酶抑制剂在制备治疗小儿肺炎的药物中的用途 |
| IT202200007808A1 (it) * | 2022-04-20 | 2023-10-20 | Luigi Michele Pavone | Composizioni terapeutiche per malattie causate da accumulo di eparan solfato |
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|---|---|---|---|---|
| US8013A (en) * | 1851-04-01 | Improvement in wheat-fans | ||
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
| DE2834122A1 (de) * | 1978-08-03 | 1980-02-14 | Bayer Ag | Verfahren zur herstellung von 6-amino-6-desoxy-l-sorbose |
| DE2839309A1 (de) * | 1978-09-09 | 1980-03-27 | Bayer Ag | 3,4,5-trihydroxypiperidin-derivate |
| DE2853573A1 (de) * | 1978-12-12 | 1980-07-03 | Bayer Ag | Herstellung von n-substituierten derivaten des l-desoxynojirimycins |
| DE3038901A1 (de) * | 1980-10-15 | 1982-05-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins |
| DE3611841A1 (de) * | 1986-04-09 | 1987-10-15 | Bayer Ag | Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten |
| US5103008A (en) * | 1989-08-17 | 1992-04-07 | Monsanto Company | Compound, N-butyl-deoxynojirimycin-6-phosphate |
| US5043273A (en) * | 1989-08-17 | 1991-08-27 | Monsanto Company | Phosphorylated glycosidase inhibitor prodrugs |
| US4994572A (en) * | 1989-10-12 | 1991-02-19 | Monsanto Company | Synthesis of nojirimycin derivatives |
| US5030638A (en) * | 1990-02-26 | 1991-07-09 | G. D. Searle & Co. | Method of antiviral enhancement |
| US5200523A (en) * | 1990-10-10 | 1993-04-06 | Monsanto Company | Synthesis of nojirimycin derivatives |
| US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
| US5399567A (en) * | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
| AU1876095A (en) * | 1994-02-25 | 1995-09-11 | G.D. Searle & Co. | Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus |
| CN1290168A (zh) * | 1997-12-11 | 2001-04-04 | 牛津大学院长校长专家委员会 | 膜相关病毒复制的抑制 |
| US6689759B1 (en) * | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
| US6610703B1 (en) * | 1998-12-10 | 2003-08-26 | G.D. Searle & Co. | Method for treatment of glycolipid storage diseases |
| GB9828474D0 (en) * | 1998-12-24 | 1999-02-17 | British Aerospace | Surface topology inspection |
| JP2002536407A (ja) * | 1999-02-12 | 2002-10-29 | ジー・ディー・サール・アンド・カンパニー | 肝炎ウィルス感染の治療のための置換−１，５−ジデオキシ−１，５−イミノ−ｄ−グルシトール化合物の使用 |
| GB0100889D0 (en) * | 2001-01-12 | 2001-02-21 | Oxford Glycosciences Uk Ltd | Compounds |
| EP1196190B1 (en) * | 1999-07-26 | 2003-03-19 | G.D. SEARLE & CO. | Use of long-chain n-alkyl derivatives of deoxynojirimycin and a glucocerebrosidase enzyme for the manufacture of a medicament for the treatment of glycolipid storage diseases |
| US7256005B2 (en) * | 1999-08-10 | 2007-08-14 | The Chancellor, Masters And Scholars Of The University Of Oxford | Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity |
| ATE382351T1 (de) * | 1999-08-10 | 2008-01-15 | Univ Oxford | Langkettige n-alkyl verbindungen und deren oxa- derivate zur verwendung als anitvirale mittel |
| CA2814767C (en) * | 2003-01-31 | 2016-03-15 | Mount Sinai School Of Medicine Of New York University | Combination therapy for treating protein deficiency disorders |
| US7446098B2 (en) * | 2003-02-18 | 2008-11-04 | Mount Sinai School Of Medicine Of New York University | Combination therapy for treating protein deficiencies |
| US20050256168A1 (en) * | 2004-04-28 | 2005-11-17 | Block Timothy M | Compositions for oral administration for the treatment of interferon-responsive disorders |
| US7524829B2 (en) * | 2004-11-01 | 2009-04-28 | Avi Biopharma, Inc. | Antisense antiviral compounds and methods for treating a filovirus infection |
| GB0501352D0 (en) * | 2005-01-21 | 2005-03-02 | Slingsby Jason H | Use of glycosylation modulators in combination with membrane fusion inhibitors for treatment of infections caused by viruses bearing glycosylated envelope |
| JP2008533175A (ja) * | 2005-03-16 | 2008-08-21 | ユニバーシティ・オブ・オックスフォード | Ｈｉｖ−１のためのマンノース免疫原 |
| EP3441090A1 (en) * | 2005-05-17 | 2019-02-13 | Amicus Therapeutics, Inc. | A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives |
| JP2009507770A (ja) * | 2005-07-27 | 2009-02-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイティド | 眼性疾患の治療への、熱ショックの使用 |
| KR20080033463A (ko) * | 2005-07-27 | 2008-04-16 | 유니버시티 오브 플로리다 리서치 파운데이션, 아이엔씨. | 단백질 미스폴딩을 보정하는 작은 화합물 및 그의 용도 |
| US20070244184A1 (en) * | 2006-01-09 | 2007-10-18 | Simon Fraser University | Glycosidase inhibitors and methods of synthesizing same |
| CA2650311A1 (en) * | 2006-04-24 | 2007-11-01 | Academisch Medisch Centrum | Improved treatment of cystic fibrosis |
| US8975280B2 (en) * | 2006-05-24 | 2015-03-10 | The Chancellor, Masters And Scholars Of The University Of Oxford | Deoxynojirimycin and D-arabinitol analogs and methods of using |
| EP2049126A2 (en) * | 2006-08-02 | 2009-04-22 | United Therapeutics Corporation | Liposome treatment of viral infections |
| US20080131398A1 (en) * | 2006-08-21 | 2008-06-05 | United Therapeutics Corporation | Combination therapy for treatment of viral infections |
| CN101172127B (zh) * | 2006-10-31 | 2011-12-07 | 上海市新文达生物科技有限公司 | 一种桑叶提取物及其在制备抗甲型流感病毒药物中的应用 |
| US20090252785A1 (en) * | 2008-03-26 | 2009-10-08 | University Of Oxford | Endoplasmic reticulum targeting liposomes |
| CN101278977B (zh) * | 2008-03-31 | 2012-05-30 | 广州唐百服生物科技有限公司 | 一种桑叶主要活性成分的提取方法及其提取物用途 |
-
2010
- 2010-09-01 EP EP10814409.8A patent/EP2473482B1/en not_active Not-in-force
- 2010-09-01 US US12/873,704 patent/US20110065752A1/en not_active Abandoned
- 2010-09-01 CN CN201080048403.3A patent/CN102625796B/zh not_active Expired - Fee Related
- 2010-09-01 MX MX2012002486A patent/MX2012002486A/es active IP Right Grant
- 2010-09-01 CA CA2772875A patent/CA2772875A1/en not_active Abandoned
- 2010-09-01 ES ES10814409.8T patent/ES2466027T3/es active Active
- 2010-09-01 JP JP2012528002A patent/JP5653438B2/ja not_active Expired - Fee Related
- 2010-09-01 BR BR112012004676A patent/BR112012004676A2/pt not_active IP Right Cessation
- 2010-09-01 KR KR1020127007709A patent/KR101497194B1/ko not_active IP Right Cessation
- 2010-09-01 DK DK10814409.8T patent/DK2473482T3/da active
- 2010-09-01 PL PL10814409T patent/PL2473482T3/pl unknown
- 2010-09-01 WO PCT/US2010/047488 patent/WO2011028775A1/en active Application Filing
-
2016
- 2016-05-04 US US15/145,981 patent/US20160243096A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL2473482T3 (pl) | 2014-09-30 |
| WO2011028775A1 (en) | 2011-03-10 |
| DK2473482T3 (en) | 2014-05-12 |
| CN102625796B (zh) | 2015-03-11 |
| ES2466027T3 (es) | 2014-06-09 |
| EP2473482A1 (en) | 2012-07-11 |
| US20160243096A1 (en) | 2016-08-25 |
| EP2473482B1 (en) | 2014-03-05 |
| MX2012002486A (es) | 2012-09-07 |
| US20110065752A1 (en) | 2011-03-17 |
| CN102625796A (zh) | 2012-08-01 |
| JP5653438B2 (ja) | 2015-01-14 |
| JP2013503880A (ja) | 2013-02-04 |
| CA2772875A1 (en) | 2011-03-10 |
| KR20120080584A (ko) | 2012-07-17 |
| EP2473482A4 (en) | 2013-01-16 |
| KR101497194B1 (ko) | 2015-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |