BRPI0922716A2 - purificação de polipeptídeo - Google Patents

purificação de polipeptídeo

Info

Publication number
BRPI0922716A2
BRPI0922716A2 BRPI0922716A BRPI0922716A BRPI0922716A2 BR PI0922716 A2 BRPI0922716 A2 BR PI0922716A2 BR PI0922716 A BRPI0922716 A BR PI0922716A BR PI0922716 A BRPI0922716 A BR PI0922716A BR PI0922716 A2 BRPI0922716 A2 BR PI0922716A2
Authority
BR
Brazil
Prior art keywords
polypeptide purification
polypeptide
purification
Prior art date
Application number
BRPI0922716A
Other languages
English (en)
Inventor
Jais Rose Bjelke
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of BRPI0922716A2 publication Critical patent/BRPI0922716A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
BRPI0922716A 2008-12-02 2009-12-01 purificação de polipeptídeo BRPI0922716A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08170454 2008-12-02
PCT/EP2009/066149 WO2010063717A1 (en) 2008-12-02 2009-12-01 Polypeptide purification

Publications (1)

Publication Number Publication Date
BRPI0922716A2 true BRPI0922716A2 (pt) 2016-11-01

Family

ID=40404199

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922716A BRPI0922716A2 (pt) 2008-12-02 2009-12-01 purificação de polipeptídeo

Country Status (12)

Country Link
US (1) US20110287518A1 (pt)
EP (1) EP2373677B1 (pt)
JP (1) JP5788803B2 (pt)
KR (1) KR101821143B1 (pt)
CN (1) CN102239175A (pt)
AU (1) AU2009324204B2 (pt)
BR (1) BRPI0922716A2 (pt)
CA (1) CA2742246A1 (pt)
ES (1) ES2576109T3 (pt)
MX (1) MX2011005474A (pt)
RU (1) RU2544860C2 (pt)
WO (1) WO2010063717A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102666568B (zh) * 2009-12-18 2015-12-09 杰特有限公司 纯化多肽的方法
JP6250931B2 (ja) 2010-01-18 2017-12-20 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 血液凝固因子の精製
SG193545A1 (en) * 2011-03-29 2013-11-29 Glaxosmithkline Llc Buffer system for protein purification
WO2013026803A1 (en) 2011-08-25 2013-02-28 F. Hoffmann-La Roche Ag Cation and anion exchange chromatography method
WO2016135719A1 (en) * 2015-02-25 2016-09-01 Omrix Biopharmaceuticals Ltd. Method for purifying and quantifying thrombin and its degradation polypeptides
WO2016207328A1 (en) * 2015-06-24 2016-12-29 Glycotope Gmbh PROCESS FOR THE PURIFICATION OF γ-CARBOXYLATED POLYPEPTIDES
CN109415427A (zh) * 2016-07-15 2019-03-01 豪夫迈·罗氏有限公司 用于纯化聚乙二醇化的促红细胞生成素的方法
CN114599971A (zh) * 2019-10-14 2022-06-07 皮尔斯生物科技有限公司 肽纯化配制物和方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
IT1262899B (it) 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
CN101818138A (zh) * 2003-03-18 2010-09-01 诺和诺德医疗保健公司 生产含有gla残基的丝氨酸蛋白酶的方法
BRPI0519626A2 (pt) * 2004-12-23 2009-02-25 Novo Nordisk Healthcare Ag mÉtodos para a reduÇço do teor de um ou mais contaminantes, do teor de proteÍna s em uma composiÇço, do teor de um ou mais contaminantes de proteÍna em um sobrenadante de cultura de cÉlula, do teor de proteÍna s em um sobrenadante de cultura de cÉlula, composiÇço compreendendo uma proteÍna dependente de vitamina k de interesse
DK2125866T3 (da) * 2007-02-28 2013-07-29 Baxter Int Fremgangsmåde til rensning af rekombinant blodkoagulationsfaktor IX, som er beriget med sulfaterede og/eller phosphorylerede molekyler

Also Published As

Publication number Publication date
CN102239175A (zh) 2011-11-09
WO2010063717A1 (en) 2010-06-10
CA2742246A1 (en) 2010-06-10
EP2373677A1 (en) 2011-10-12
JP2012510500A (ja) 2012-05-10
EP2373677B1 (en) 2016-03-23
AU2009324204A1 (en) 2010-06-10
MX2011005474A (es) 2011-06-16
RU2544860C2 (ru) 2015-03-20
RU2011125656A (ru) 2013-01-10
US20110287518A1 (en) 2011-11-24
ES2576109T3 (es) 2016-07-05
AU2009324204B2 (en) 2014-10-16
JP5788803B2 (ja) 2015-10-07
KR20110099251A (ko) 2011-09-07
KR101821143B1 (ko) 2018-01-23

Similar Documents

Publication Publication Date Title
BRPI0919237A2 (pt) purificação de policarbonatos
BRPI0921327A2 (pt) Combinação de herbicida-protetor
BRPI0906764A2 (pt) Processos
BRPI0907457A2 (pt) Absorventes
BRPI0907376A2 (pt) Fotobiorretador
DE602009000234D1 (de) msignals
DE602008003972D1 (de) Sitzrücklehnungsmechanismus
DE602008003521D1 (de) Sitzrücklehnungsmechanismus
DK2336132T3 (da) Morpholinpurinderivat
DK2335031T3 (da) In-line-måler
DK2598514T3 (da) Proteinoprensning
DE602008003970D1 (de) Strahlstromkalibriersystem
BRPI0813830A2 (pt) Purificação de polipeptídeos peguilados
BRPI0923541A2 (pt) purificação de imunoglobulina
DK2271613T3 (da) Hydroxymethylcyklohexylaminer
BRPI0907522A2 (pt) biarlamidas
BRPI1010661A2 (pt) peptídeo
BRPI0909634A2 (pt) 2-aminoquinolinas
BRPI0922716A2 (pt) purificação de polipeptídeo
BR112012006603A2 (pt) braçadeira de fixação
BRPI0922728A2 (pt) combinação de herbicida-antídoto
DE112009001946A5 (de) Mobelauszugsführung
DE602009000488D1 (de) Obstvereinzelvorrichtung
BRPI0907863A2 (pt) pirrolopirimidinacarboxamidas
BRPI0909637A2 (pt) 2-aminoquinolinas

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: NOVO NORDISK HEALTH CARE AG (CH)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B10A Cessation: cessation confirmed