BRPI0921263A2 - Anticorpos antir-receptor de tgf-beta ll - Google Patents
Anticorpos antir-receptor de tgf-beta llInfo
- Publication number
- BRPI0921263A2 BRPI0921263A2 BRPI0921263-9A BRPI0921263A BRPI0921263A2 BR PI0921263 A2 BRPI0921263 A2 BR PI0921263A2 BR PI0921263 A BRPI0921263 A BR PI0921263A BR PI0921263 A2 BRPI0921263 A2 BR PI0921263A2
- Authority
- BR
- Brazil
- Prior art keywords
- tgf
- beta
- receptor antibodies
- antibodies
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19869708P | 2008-11-07 | 2008-11-07 | |
| US17036909P | 2009-04-17 | 2009-04-17 | |
| PCT/US2009/062450 WO2010053814A1 (en) | 2008-11-07 | 2009-10-29 | Anti-tgf-beta receptor ii antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0921263A2 true BRPI0921263A2 (pt) | 2015-08-04 |
Family
ID=41508691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0921263-9A BRPI0921263A2 (pt) | 2008-11-07 | 2009-10-29 | Anticorpos antir-receptor de tgf-beta ll |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8147834B2 (pt) |
| EP (1) | EP2356152A1 (pt) |
| JP (1) | JP5667067B2 (pt) |
| KR (1) | KR101283856B1 (pt) |
| CN (1) | CN102209727B (pt) |
| AR (1) | AR073909A1 (pt) |
| AU (1) | AU2009311375B2 (pt) |
| BR (1) | BRPI0921263A2 (pt) |
| CA (1) | CA2742961C (pt) |
| EA (1) | EA025169B1 (pt) |
| IL (1) | IL211842A (pt) |
| JO (1) | JO3096B1 (pt) |
| MX (1) | MX2011004871A (pt) |
| NZ (1) | NZ591943A (pt) |
| PA (1) | PA8846101A1 (pt) |
| SG (1) | SG10201401280TA (pt) |
| TW (1) | TWI384998B (pt) |
| WO (1) | WO2010053814A1 (pt) |
| ZA (1) | ZA201103178B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2823104A1 (en) * | 2011-01-06 | 2012-07-12 | Glaxo Group Limited | Ligands that bind tgf-beta receptor ii |
| AR086044A1 (es) | 2011-05-12 | 2013-11-13 | Imclone Llc | Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos |
| CA2975147A1 (en) | 2015-01-31 | 2016-08-04 | Yangbing Zhao | Compositions and methods for t cell delivery of therapeutic molecules |
| LT3370768T (lt) | 2015-11-03 | 2022-05-25 | Janssen Biotech, Inc. | Antikūnai, specifiškai surišantys pd-1, ir jų panaudojimas |
| BR112018068340A2 (pt) | 2016-03-11 | 2019-01-15 | Scholar Rock Inc | imunoglobulinas de ligação ao tgfss1 e usos destas |
| TW201825519A (zh) | 2016-10-18 | 2018-07-16 | 美商美國禮來大藥廠 | TGFβ受體II抗體 |
| CN106884005A (zh) * | 2017-01-19 | 2017-06-23 | 樊克兴 | 一种结直肠癌抗原特异性t细胞的制备方法 |
| AU2018355244A1 (en) | 2017-10-24 | 2020-04-09 | Crispr Therapeutics Ag | Compositions and methods for the depletion of CD117+ cells |
| US10882915B2 (en) | 2017-10-24 | 2021-01-05 | Magenta Therapeutics, Inc. | Compositions and methods for the depletion of CD117+ cells |
| WO2019084053A1 (en) * | 2017-10-24 | 2019-05-02 | Magenta Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS |
| CN107973853B (zh) * | 2017-12-12 | 2021-04-30 | 山西农业大学 | 一种利用特征多肽制备Smad2蛋白特异性抗体的方法及其应用 |
| KR20230145542A (ko) | 2019-12-24 | 2023-10-17 | 메뤼스 엔.페. | Tgf-베타-rii 결합 단백질 |
| KR102314157B1 (ko) * | 2020-01-10 | 2021-10-19 | 주식회사 뉴클릭스바이오 | TGF-β 수용체에 특이적으로 결합하는 항체 및 이의 이용방법 |
| WO2023198194A1 (en) * | 2022-04-15 | 2023-10-19 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-cd40 antibodies and uses thereof |
| CN116178567A (zh) * | 2022-10-28 | 2023-05-30 | 四川大学华西医院 | 一种靶向TGFβRII的嵌合抗原受体及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| JP4124815B2 (ja) | 1991-10-31 | 2008-07-23 | ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ | ＴＧＦ−β型受容体ｃＤＮＡおよびその用途 |
| JP2001206899A (ja) * | 1999-11-18 | 2001-07-31 | Japan Tobacco Inc | ＴＧＦ−βＩＩ型受容体に対するヒトモノクローナル抗体及びその医薬用途 |
| JP2004121001A (ja) * | 2002-08-07 | 2004-04-22 | Japan Tobacco Inc | ＴＧＦ−βＩＩ型受容体に対する高親和性モノクローナル抗体 |
| EP1992360A4 (en) | 2006-02-01 | 2010-02-17 | Univ Tokyo | USE IN ASSOCIATION OF A TGF-BETA SIGNAL INHIBITOR AND ANTITUMMER AGENT |
-
2009
- 2009-10-18 JO JOP/2009/0382A patent/JO3096B1/ar active
- 2009-10-19 TW TW098135300A patent/TWI384998B/zh not_active IP Right Cessation
- 2009-10-19 AR ARP090104017A patent/AR073909A1/es unknown
- 2009-10-19 PA PA20098846101A patent/PA8846101A1/es unknown
- 2009-10-29 SG SG10201401280TA patent/SG10201401280TA/en unknown
- 2009-10-29 US US12/608,034 patent/US8147834B2/en not_active Expired - Fee Related
- 2009-10-29 NZ NZ591943A patent/NZ591943A/xx not_active IP Right Cessation
- 2009-10-29 EP EP09745224A patent/EP2356152A1/en not_active Withdrawn
- 2009-10-29 CA CA2742961A patent/CA2742961C/en not_active Expired - Fee Related
- 2009-10-29 EA EA201170659A patent/EA025169B1/ru not_active IP Right Cessation
- 2009-10-29 BR BRPI0921263-9A patent/BRPI0921263A2/pt not_active IP Right Cessation
- 2009-10-29 KR KR1020117010399A patent/KR101283856B1/ko not_active IP Right Cessation
- 2009-10-29 WO PCT/US2009/062450 patent/WO2010053814A1/en active Application Filing
- 2009-10-29 AU AU2009311375A patent/AU2009311375B2/en not_active Ceased
- 2009-10-29 CN CN200980144391.1A patent/CN102209727B/zh not_active Expired - Fee Related
- 2009-10-29 JP JP2011534731A patent/JP5667067B2/ja not_active Expired - Fee Related
- 2009-10-29 MX MX2011004871A patent/MX2011004871A/es active IP Right Grant
-
2011
- 2011-03-21 IL IL211842A patent/IL211842A/en not_active IP Right Cessation
- 2011-04-29 ZA ZA2011/03178A patent/ZA201103178B/en unknown
-
2012
- 2012-02-20 US US13/400,308 patent/US20120177666A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20110067155A (ko) | 2011-06-21 |
| CA2742961C (en) | 2016-08-30 |
| US20120177666A1 (en) | 2012-07-12 |
| AU2009311375A1 (en) | 2010-05-14 |
| PA8846101A1 (es) | 2010-06-28 |
| CN102209727B (zh) | 2014-07-30 |
| EP2356152A1 (en) | 2011-08-17 |
| WO2010053814A1 (en) | 2010-05-14 |
| JP2012508170A (ja) | 2012-04-05 |
| JO3096B1 (ar) | 2017-03-15 |
| IL211842A0 (en) | 2011-06-30 |
| TW201026326A (en) | 2010-07-16 |
| SG10201401280TA (en) | 2014-05-29 |
| AR073909A1 (es) | 2010-12-09 |
| US8147834B2 (en) | 2012-04-03 |
| KR101283856B1 (ko) | 2013-07-15 |
| IL211842A (en) | 2016-09-29 |
| NZ591943A (en) | 2012-11-30 |
| AU2009311375B2 (en) | 2014-07-31 |
| CN102209727A (zh) | 2011-10-05 |
| MX2011004871A (es) | 2011-07-13 |
| TWI384998B (zh) | 2013-02-11 |
| JP5667067B2 (ja) | 2015-02-12 |
| ZA201103178B (en) | 2012-10-31 |
| EA025169B1 (ru) | 2016-11-30 |
| EA201170659A1 (ru) | 2011-10-31 |
| CA2742961A1 (en) | 2010-05-14 |
| US20100119516A1 (en) | 2010-05-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY2019004I2 (el) | Τροποποιημενα αντισωματα αντι-ιl-23ρ19 | |
| BRPI0921263A2 (pt) | Anticorpos antir-receptor de tgf-beta ll | |
| HK1222397A1 (zh) | 診斷抗體測定 | |
| BRPI0820819A2 (pt) | Formulação de anticorpos | |
| BRPI0906877A2 (pt) | Anticorpos anti-trkb aperfeiçoados | |
| BRPI0922730A2 (pt) | formulação de anticorpo | |
| BRPI0920648A2 (pt) | Combinações pesticidas contendo sulfoxaflor | |
| BRPI0907237A2 (pt) | Anticorpo anti-cldn6 | |
| BRPI0814003A2 (pt) | Formulações de anticorpo | |
| BRPI0814252A2 (pt) | Formulações de anticorpo | |
| BRPI0922800A2 (pt) | anticorpos c-met | |
| BRPI0815567A2 (pt) | Anticorpos híbridos antialfa v-integrina projetados | |
| BRPI0909644A2 (pt) | dispositivo de foto-epilação | |
| BRPI0917888A2 (pt) | Formulação de anticorpo líquida estável | |
| DE602008006646D1 (de) | Fahrzeugstrukturelement | |
| BRPI0910229A2 (pt) | Tetramatos de 4';4'-dioxaspiro espirociclicamente substituídos | |
| UY3847Q (es) | Lata | |
| BRPI0807991A2 (pt) | Anticorpos anti-il-23r elaborados. | |
| BRPI0913961A2 (pt) | dispositivo de amortecimento | |
| DE112008002581A5 (de) | Antriebsstrang | |
| BRPI0817427A2 (pt) | Anticorpo anti-bst2 | |
| BRPI0909633A2 (pt) | anticorpos anti-tyrp1 | |
| DE112007003038A5 (de) | Antriebsstrang | |
| BRPI0819765A2 (pt) | Conjugados de anticorpos anti-rg-1 | |
| BRPI0912769A2 (pt) | anticorpos anti-pirb |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2538 DE 27-08-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |