BRPI0918233B8 - métodos de triagem para a lesão pulmonar aguda e doença do enxerto contra hospedeiro relacionada à transfusão ou transplante, kits e uso de polipeptídeos - Google Patents
métodos de triagem para a lesão pulmonar aguda e doença do enxerto contra hospedeiro relacionada à transfusão ou transplante, kits e uso de polipeptídeosInfo
- Publication number
- BRPI0918233B8 BRPI0918233B8 BRPI0918233A BRPI0918233A BRPI0918233B8 BR PI0918233 B8 BRPI0918233 B8 BR PI0918233B8 BR PI0918233 A BRPI0918233 A BR PI0918233A BR PI0918233 A BRPI0918233 A BR PI0918233A BR PI0918233 B8 BRPI0918233 B8 BR PI0918233B8
- Authority
- BR
- Brazil
- Prior art keywords
- hna
- transfusion
- kits
- polypeptides
- lung injury
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000012216 screening Methods 0.000 title abstract 3
- 208000009329 Graft vs Host Disease Diseases 0.000 title 1
- 206010069351 acute lung injury Diseases 0.000 title 1
- 208000024908 graft versus host disease Diseases 0.000 title 1
- 101150116431 Slc44a2 gene Proteins 0.000 abstract 1
- 208000007587 Transfusion-Related Acute Lung Injury Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008045696A DE102008045696A1 (de) | 2008-09-04 | 2008-09-04 | Granulozyten HNA-3a/b-Antigen |
| DE102008045696.9 | 2008-09-04 | ||
| PCT/EP2009/006386 WO2010025915A1 (en) | 2008-09-04 | 2009-09-03 | Screening methods for transfusion related acute lung injury (trali) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0918233A2 BRPI0918233A2 (pt) | 2015-12-15 |
| BRPI0918233B1 BRPI0918233B1 (pt) | 2020-12-01 |
| BRPI0918233B8 true BRPI0918233B8 (pt) | 2021-07-27 |
Family
ID=41266687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0918233A BRPI0918233B8 (pt) | 2008-09-04 | 2009-09-03 | métodos de triagem para a lesão pulmonar aguda e doença do enxerto contra hospedeiro relacionada à transfusão ou transplante, kits e uso de polipeptídeos |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US8084216B2 (enExample) |
| EP (1) | EP2321644B1 (enExample) |
| JP (1) | JP5766606B2 (enExample) |
| CN (1) | CN102203609B (enExample) |
| AU (2) | AU2009289809B2 (enExample) |
| BR (1) | BRPI0918233B8 (enExample) |
| CA (1) | CA2735138C (enExample) |
| DE (1) | DE102008045696A1 (enExample) |
| WO (1) | WO2010025915A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5220104B2 (ja) | 2007-05-29 | 2013-06-26 | ラブ・パートナーズ・アソシエイツ・インコーポレーテッド | カメラとワイヤレスデバイスとの間のホットシュー通信を維持するためのシステムおよび方法 |
| WO2009114522A2 (en) * | 2008-03-10 | 2009-09-17 | Bonfils Blood Center | Compositions, kits and methods for determining etiology of trali and detecting patients at risk for this transfusion reaction |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
| US20110223603A1 (en) * | 2008-11-21 | 2011-09-15 | Martin Heath Bluth | Diagnosing and monitoring response to treatment of non-incontinent urological and related diseases |
| CN102203610A (zh) | 2008-12-01 | 2011-09-28 | 利兰·斯坦福青年大学托管委员会 | 用于检测补体结合性抗体的方法和组合物 |
| CN105308457B (zh) * | 2013-03-14 | 2018-07-10 | 斯坦福大学托管董事会 | 检测供体特异性抗体的方法和用于实施所述方法的系统 |
| US10571468B2 (en) | 2014-05-09 | 2020-02-25 | One Lambda, Inc. | Modified Fc gamma receptor type III (FCγIII, HNA-1) polypeptides and the uses thereof |
| US10527613B2 (en) | 2015-11-10 | 2020-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker detection methods and systems and kits for practicing same |
| WO2017094733A1 (ja) * | 2015-11-30 | 2017-06-08 | 日産化学工業株式会社 | 分子標的医薬に結合するdnaアプタマー及びそれを用いる分子標的医薬の検出方法 |
| US11065301B2 (en) * | 2016-04-15 | 2021-07-20 | Pontificia Universidad Catolica De Chile | Pharmaceutical composition for ameliorating the symptoms and disease of the respiratory infection caused by human metapneumovirus (HMPV), which comprises at least one agent that neutralizes the function of TSLP and/or TSLPR and/or OX40L and/or CD177 molecules, and a pharmaceutically acceptable excipient, and use thereof |
| CN116083551B (zh) * | 2022-10-11 | 2025-02-21 | 南宁中心血站(南宁输血医学研究所) | 用于检测人类中性粒细胞抗原基因分型的引物组合、试剂盒及方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7368531B2 (en) | 1997-03-07 | 2008-05-06 | Human Genome Sciences, Inc. | Human secreted proteins |
| US7411051B2 (en) | 1997-03-07 | 2008-08-12 | Human Genome Sciences, Inc. | Antibodies to HDPPA04 polypeptide |
| US20030082646A1 (en) | 1998-12-29 | 2003-05-01 | The Regents Of The University Of Michigan | Antigenic targets of autoimmune sensorineural hearing loss (AISNHL) and development of tests for diagnosis and management of AISNHL |
| WO2000058473A2 (en) | 1999-03-31 | 2000-10-05 | Curagen Corporation | Nucleic acids including open reading frames encoding polypeptides; 'orfx' |
| US6943235B1 (en) | 1999-04-12 | 2005-09-13 | Agensys, Inc. | Transmembrane protein expressed in prostate cancer |
| EP1074617A3 (en) | 1999-07-29 | 2004-04-21 | Research Association for Biotechnology | Primers for synthesising full-length cDNA and their use |
| FR2800750B1 (fr) | 1999-11-05 | 2003-01-31 | Centre Nat Rech Scient | Proteines membranaires ctl (choline transporter like) impliquees dans le transport de la choline |
| DE10028725B4 (de) | 2000-06-09 | 2013-03-21 | Jürgen Bux | Primärstruktur des HNA-2a (ehemals NB1)-Antigens |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| US20030219777A1 (en) * | 2001-12-18 | 2003-11-27 | Lynx Therapeutics, Inc. | Identification of candidate genes for the atherosclerosis susceptibility locus (ATHS) |
| US7829292B2 (en) | 2002-05-06 | 2010-11-09 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing, predicting therapeutic response of, and monitoring autoimmune disease |
| DE10228103A1 (de) | 2002-06-24 | 2004-01-15 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
| CA2516128A1 (en) * | 2003-02-14 | 2004-09-02 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
| US7303985B2 (en) | 2003-11-17 | 2007-12-04 | Intel Corporation | Zeolite-carbon doped oxide composite low k dielectric |
| EP2006375A4 (en) * | 2006-03-23 | 2013-05-08 | Japan Red Cross | SAMPLE CELL USED FOR THE DETECTION OF ANTI-GRANULOCYTIC ANTIBODIES |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
-
2008
- 2008-09-04 DE DE102008045696A patent/DE102008045696A1/de not_active Withdrawn
-
2009
- 2009-09-03 EP EP09778306.2A patent/EP2321644B1/en active Active
- 2009-09-03 CN CN200980144058.0A patent/CN102203609B/zh active Active
- 2009-09-03 WO PCT/EP2009/006386 patent/WO2010025915A1/en not_active Ceased
- 2009-09-03 AU AU2009289809A patent/AU2009289809B2/en active Active
- 2009-09-03 JP JP2011525460A patent/JP5766606B2/ja active Active
- 2009-09-03 CA CA2735138A patent/CA2735138C/en active Active
- 2009-09-03 US US12/553,487 patent/US8084216B2/en active Active
- 2009-09-03 BR BRPI0918233A patent/BRPI0918233B8/pt active IP Right Grant
-
2011
- 2011-11-29 US US13/306,380 patent/US8435733B2/en active Active
-
2013
- 2013-03-18 US US13/845,898 patent/US8999651B2/en active Active
-
2015
- 2015-04-03 US US14/678,827 patent/US9963741B2/en active Active
-
2016
- 2016-06-17 AU AU2016204135A patent/AU2016204135A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US8084216B2 (en) | 2011-12-27 |
| JP2012501631A (ja) | 2012-01-26 |
| JP5766606B2 (ja) | 2015-08-19 |
| EP2321644B1 (en) | 2016-12-14 |
| CN102203609B (zh) | 2017-07-11 |
| US20150203915A1 (en) | 2015-07-23 |
| US20100055706A1 (en) | 2010-03-04 |
| CA2735138C (en) | 2021-06-01 |
| WO2010025915A1 (en) | 2010-03-11 |
| US9963741B2 (en) | 2018-05-08 |
| US8999651B2 (en) | 2015-04-07 |
| AU2016204135A1 (en) | 2016-07-14 |
| AU2009289809A8 (en) | 2011-05-12 |
| US8435733B2 (en) | 2013-05-07 |
| BRPI0918233B1 (pt) | 2020-12-01 |
| EP2321644A1 (en) | 2011-05-18 |
| US20130189696A1 (en) | 2013-07-25 |
| US20120070834A1 (en) | 2012-03-22 |
| CN102203609A (zh) | 2011-09-28 |
| AU2009289809B2 (en) | 2016-07-07 |
| BRPI0918233A2 (pt) | 2015-12-15 |
| DE102008045696A1 (de) | 2010-03-11 |
| CA2735138A1 (en) | 2010-03-11 |
| AU2009289809A1 (en) | 2010-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/12/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/09/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |