BRPI0915173A2 - Nucleotídeos e nucleosídeos e métodos para uso dos mesmos em sequenciamento de dna - Google Patents
Nucleotídeos e nucleosídeos e métodos para uso dos mesmos em sequenciamento de dnaInfo
- Publication number
- BRPI0915173A2 BRPI0915173A2 BRPI0915173-7A BRPI0915173A BRPI0915173A2 BR PI0915173 A2 BRPI0915173 A2 BR PI0915173A2 BR PI0915173 A BRPI0915173 A BR PI0915173A BR PI0915173 A2 BRPI0915173 A2 BR PI0915173A2
- Authority
- BR
- Brazil
- Prior art keywords
- nucleosides
- nucleotides
- methods
- dna sequencing
- sequencing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/117—Modifications characterised by incorporating modified base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6079508P | 2008-06-11 | 2008-06-11 | |
US61/060,795 | 2008-06-11 | ||
US18477909P | 2009-06-05 | 2009-06-05 | |
US61/184,779 | 2009-06-05 | ||
PCT/US2009/047071 WO2009152353A2 (en) | 2008-06-11 | 2009-06-11 | Nucleotides and nucleosides and methods for their use in dna sequencing |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0915173A2 true BRPI0915173A2 (pt) | 2015-08-18 |
BRPI0915173B1 BRPI0915173B1 (pt) | 2021-05-04 |
BRPI0915173B8 BRPI0915173B8 (pt) | 2021-05-25 |
Family
ID=41417396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0915173A BRPI0915173B8 (pt) | 2008-06-11 | 2009-06-11 | compostos de nucleotídeos e nucleosídeos e método de sequenciamento de um ácido nucleico-alvo |
Country Status (15)
Country | Link |
---|---|
US (4) | US8148503B2 (pt) |
EP (1) | EP2307565B1 (pt) |
JP (1) | JP5143953B2 (pt) |
KR (1) | KR101677772B1 (pt) |
CN (2) | CN102264917B (pt) |
AU (1) | AU2009257369B2 (pt) |
BR (1) | BRPI0915173B8 (pt) |
CA (2) | CA2727709C (pt) |
EA (1) | EA201100001A3 (pt) |
HK (1) | HK1163184A1 (pt) |
IL (1) | IL209917A (pt) |
MX (1) | MX2010013678A (pt) |
NZ (2) | NZ594812A (pt) |
WO (1) | WO2009152353A2 (pt) |
ZA (1) | ZA201100122B (pt) |
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KR101677772B1 (ko) | 2008-06-11 | 2016-11-18 | 레이저젠, 인코퍼레이티드 | 뉴클레오타이드 및 뉴클레오사이드 그리고 시퀀싱에서의 이들의 이용 방법 |
CN104328109A (zh) * | 2008-09-22 | 2015-02-04 | 霍夫曼-拉罗奇有限公司 | 微阵列底物上的生物材料的选择性处理 |
CN103282518B (zh) * | 2010-12-17 | 2016-11-16 | 纽约哥伦比亚大学理事会 | 使用经修饰的核苷酸和纳米孔检测的dna边合成边测序 |
EP3670523B1 (en) | 2011-09-13 | 2021-08-11 | Agilent Technologies, Inc. | 3'-oh unblocked, fast photocleavable terminating nucleotides and their use in methods for nucleic acid sequencing |
EP2850514A4 (en) * | 2012-05-18 | 2016-03-02 | Univ Georgetown | METHOD AND SYSTEMS FOR FACILITATING AND SEARCHING A DATABASE OF INFORMATION ON MEDICINAL PRODUCTS |
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WO2014150851A1 (en) | 2013-03-15 | 2014-09-25 | Ibis Biosciences, Inc. | Nucleotide analogs for sequencing |
US9591268B2 (en) | 2013-03-15 | 2017-03-07 | Qiagen Waltham, Inc. | Flow cell alignment methods and systems |
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SG11201608538UA (en) * | 2014-04-29 | 2016-11-29 | Biosearch Technologies Inc | Compounds compositions and methods including thermally labile moieties |
US10487357B2 (en) | 2014-10-03 | 2019-11-26 | Life Technologies Corporation | Methods of nucleic acid analysis using terminator nucleotides |
US10544455B2 (en) | 2014-10-03 | 2020-01-28 | Life Technologies Corporation | Sequencing methods, compositions and systems using terminator nucleotides |
WO2016065142A2 (en) | 2014-10-22 | 2016-04-28 | The Johns Hopkins University | New scaffolds and multifunctional intermediates for imaging psma and cancer therapy |
WO2016094845A2 (en) | 2014-12-12 | 2016-06-16 | Woolf Tod M | Compositions and methods for editing nucleic acids in cells utilizing oligonucleotides |
BR112018002525A2 (pt) | 2015-08-06 | 2018-09-25 | Lasergen Inc | detecção de antígenos usando marcadores fotocliváveis |
CN108603227A (zh) | 2015-11-18 | 2018-09-28 | 卡利姆·U·米尔 | 超分辨率测序 |
CA3026193A1 (en) | 2016-06-06 | 2017-12-14 | Redvault Biosciences, Lp | Target reporter constructs and uses thereof |
US11371087B2 (en) * | 2016-06-10 | 2022-06-28 | Takara Bio Usa, Inc. | Methods and compositions employing blocked primers |
GB2559117B (en) * | 2017-01-19 | 2019-11-27 | Oxford Nanopore Tech Ltd | Double stranded polynucleotide synthesis method, kit and system |
CN108752406A (zh) * | 2018-05-29 | 2018-11-06 | 苏州百源基因技术有限公司 | 一种荧光标记的核苷酸及其制备方法和用途 |
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EP4127229A4 (en) * | 2020-03-26 | 2024-04-17 | Agilent Technologies Inc | METHODS AND COMPOSITIONS FOR MULTI-STEP PRIMER EXTENSION REACTIONS |
CN113341058A (zh) * | 2021-06-09 | 2021-09-03 | 南京溯远基因科技有限公司 | 一种三色高通量测序试剂及测序方法 |
IL309368A (en) | 2021-06-29 | 2024-02-01 | Agilent Technologies Inc | polymerase mutants and use with 3'-OH UNBLOCKED REVERSIBLE TERMINATORS |
CN117858885A (zh) * | 2021-07-05 | 2024-04-09 | 国立研究开发法人科学技术振兴机构 | 核苷酸类的纯化方法和核苷酸类的纯化装置以及疏水性试剂和疏水性底物 |
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KR101677772B1 (ko) | 2008-06-11 | 2016-11-18 | 레이저젠, 인코퍼레이티드 | 뉴클레오타이드 및 뉴클레오사이드 그리고 시퀀싱에서의 이들의 이용 방법 |
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2009
- 2009-06-11 KR KR1020117000755A patent/KR101677772B1/ko active IP Right Grant
- 2009-06-11 WO PCT/US2009/047071 patent/WO2009152353A2/en active Application Filing
- 2009-06-11 CA CA2727709A patent/CA2727709C/en active Active
- 2009-06-11 CN CN200980131339.2A patent/CN102264917B/zh active Active
- 2009-06-11 CA CA2979146A patent/CA2979146C/en active Active
- 2009-06-11 JP JP2011513695A patent/JP5143953B2/ja active Active
- 2009-06-11 US US12/483,080 patent/US8148503B2/en active Active
- 2009-06-11 NZ NZ594812A patent/NZ594812A/xx not_active IP Right Cessation
- 2009-06-11 AU AU2009257369A patent/AU2009257369B2/en active Active
- 2009-06-11 BR BRPI0915173A patent/BRPI0915173B8/pt active IP Right Grant
- 2009-06-11 MX MX2010013678A patent/MX2010013678A/es active IP Right Grant
- 2009-06-11 EA EA201100001A patent/EA201100001A3/ru unknown
- 2009-06-11 EP EP09763641.9A patent/EP2307565B1/en active Active
- 2009-06-11 NZ NZ590265A patent/NZ590265A/xx not_active IP Right Cessation
- 2009-06-11 CN CN201310484701.2A patent/CN103588839B/zh active Active
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2010
- 2010-12-09 IL IL209917A patent/IL209917A/en active IP Right Grant
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2011
- 2011-01-05 ZA ZA2011/00122A patent/ZA201100122B/en unknown
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2012
- 2012-02-28 US US13/406,934 patent/US8497360B2/en active Active
- 2012-04-16 HK HK12103690.3A patent/HK1163184A1/xx not_active IP Right Cessation
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