BRPI0915173A2 - Nucleotídeos e nucleosídeos e métodos para uso dos mesmos em sequenciamento de dna - Google Patents

Nucleotídeos e nucleosídeos e métodos para uso dos mesmos em sequenciamento de dna

Info

Publication number
BRPI0915173A2
BRPI0915173A2 BRPI0915173-7A BRPI0915173A BRPI0915173A2 BR PI0915173 A2 BRPI0915173 A2 BR PI0915173A2 BR PI0915173 A BRPI0915173 A BR PI0915173A BR PI0915173 A2 BRPI0915173 A2 BR PI0915173A2
Authority
BR
Brazil
Prior art keywords
nucleosides
nucleotides
methods
dna sequencing
sequencing
Prior art date
Application number
BRPI0915173-7A
Other languages
English (en)
Inventor
Vladislav A Litosh
Megan N Hersh
Brian P Stupi
Weidong Wu
Michael L Metzker
Original Assignee
Lasergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lasergen Inc filed Critical Lasergen Inc
Publication of BRPI0915173A2 publication Critical patent/BRPI0915173A2/pt
Publication of BRPI0915173B1 publication Critical patent/BRPI0915173B1/pt
Publication of BRPI0915173B8 publication Critical patent/BRPI0915173B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10Modifications characterised by
    • C12Q2525/117Modifications characterised by incorporating modified base
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
BRPI0915173A 2008-06-11 2009-06-11 compostos de nucleotídeos e nucleosídeos e método de sequenciamento de um ácido nucleico-alvo BRPI0915173B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6079508P 2008-06-11 2008-06-11
US61/060,795 2008-06-11
US18477909P 2009-06-05 2009-06-05
US61/184,779 2009-06-05
PCT/US2009/047071 WO2009152353A2 (en) 2008-06-11 2009-06-11 Nucleotides and nucleosides and methods for their use in dna sequencing

Publications (3)

Publication Number Publication Date
BRPI0915173A2 true BRPI0915173A2 (pt) 2015-08-18
BRPI0915173B1 BRPI0915173B1 (pt) 2021-05-04
BRPI0915173B8 BRPI0915173B8 (pt) 2021-05-25

Family

ID=41417396

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0915173A BRPI0915173B8 (pt) 2008-06-11 2009-06-11 compostos de nucleotídeos e nucleosídeos e método de sequenciamento de um ácido nucleico-alvo

Country Status (15)

Country Link
US (4) US8148503B2 (pt)
EP (1) EP2307565B1 (pt)
JP (1) JP5143953B2 (pt)
KR (1) KR101677772B1 (pt)
CN (2) CN102264917B (pt)
AU (1) AU2009257369B2 (pt)
BR (1) BRPI0915173B8 (pt)
CA (2) CA2727709C (pt)
EA (1) EA201100001A3 (pt)
HK (1) HK1163184A1 (pt)
IL (1) IL209917A (pt)
MX (1) MX2010013678A (pt)
NZ (2) NZ594812A (pt)
WO (1) WO2009152353A2 (pt)
ZA (1) ZA201100122B (pt)

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Publication number Publication date
EA201100001A3 (ru) 2013-03-29
WO2009152353A2 (en) 2009-12-17
NZ590265A (en) 2012-11-30
US20100041041A1 (en) 2010-02-18
US20140051848A1 (en) 2014-02-20
AU2009257369A1 (en) 2009-12-17
US9200319B2 (en) 2015-12-01
EP2307565A2 (en) 2011-04-13
CA2727709A1 (en) 2009-12-17
IL209917A (en) 2014-06-30
US20150140559A1 (en) 2015-05-21
CN103588839A (zh) 2014-02-19
CN103588839B (zh) 2017-04-12
EA201100001A2 (ru) 2012-10-30
CA2979146C (en) 2020-07-07
MX2010013678A (es) 2011-02-24
US8877905B2 (en) 2014-11-04
IL209917A0 (en) 2011-02-28
HK1163184A1 (en) 2012-09-07
KR101677772B1 (ko) 2016-11-18
NZ594812A (en) 2012-12-21
JP5143953B2 (ja) 2013-02-13
AU2009257369B2 (en) 2015-03-26
BRPI0915173B1 (pt) 2021-05-04
US20130035237A1 (en) 2013-02-07
ZA201100122B (en) 2013-09-25
CA2727709C (en) 2017-11-14
WO2009152353A3 (en) 2013-09-26
JP2011529449A (ja) 2011-12-08
US8497360B2 (en) 2013-07-30
US8148503B2 (en) 2012-04-03
CN102264917A (zh) 2011-11-30
CN102264917B (zh) 2015-06-10
EP2307565B1 (en) 2017-11-29
CA2979146A1 (en) 2009-12-17
KR20110031191A (ko) 2011-03-24
BRPI0915173B8 (pt) 2021-05-25

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