BRPI0819018A2 - "métodos para determinar se um paciente possui risco aumentado de desenvolver hipertensão, para determinar se um paciente possui maior probalidade de se beneficiar do tratamento com um antagonista de vegf e kits para determinar se um paciente possui risco aumentado de desenvolver hipertensão e para determinar se um paciente possui maior probabilidade de se beneficiar do tratamento com um antagonista de vegf" - Google Patents
"métodos para determinar se um paciente possui risco aumentado de desenvolver hipertensão, para determinar se um paciente possui maior probalidade de se beneficiar do tratamento com um antagonista de vegf e kits para determinar se um paciente possui risco aumentado de desenvolver hipertensão e para determinar se um paciente possui maior probabilidade de se beneficiar do tratamento com um antagonista de vegf"Info
- Publication number
- BRPI0819018A2 BRPI0819018A2 BRPI0819018A BRPI0819018A2 BR PI0819018 A2 BRPI0819018 A2 BR PI0819018A2 BR PI0819018 A BRPI0819018 A BR PI0819018A BR PI0819018 A2 BRPI0819018 A2 BR PI0819018A2
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- treatment
- benefit
- increased risk
- vegf antagonist
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 101100372758 Danio rerio vegfaa gene Proteins 0.000 title 2
- 101150030763 Vegfa gene Proteins 0.000 title 2
- 239000005557 antagonist Substances 0.000 title 2
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
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- Urology & Nephrology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99161607P | 2007-11-30 | 2007-11-30 | |
| US3869908P | 2008-03-21 | 2008-03-21 | |
| PCT/US2008/084933 WO2009073540A2 (en) | 2007-11-30 | 2008-11-26 | Vegf polymorphisms and anti-angiogenesis therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0819018A2 true BRPI0819018A2 (pt) | 2015-05-05 |
Family
ID=40347982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819018 BRPI0819018A2 (pt) | 2007-11-30 | 2008-11-26 | "métodos para determinar se um paciente possui risco aumentado de desenvolver hipertensão, para determinar se um paciente possui maior probalidade de se beneficiar do tratamento com um antagonista de vegf e kits para determinar se um paciente possui risco aumentado de desenvolver hipertensão e para determinar se um paciente possui maior probabilidade de se beneficiar do tratamento com um antagonista de vegf" |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10031141B2 (enExample) |
| EP (2) | EP2220492B1 (enExample) |
| JP (3) | JP2011505145A (enExample) |
| KR (2) | KR101651796B1 (enExample) |
| CN (2) | CN102016579B (enExample) |
| AT (1) | ATE522809T1 (enExample) |
| AU (1) | AU2008334070B2 (enExample) |
| BR (1) | BRPI0819018A2 (enExample) |
| CA (1) | CA2705792A1 (enExample) |
| CY (1) | CY1112252T1 (enExample) |
| DK (1) | DK2220492T3 (enExample) |
| ES (2) | ES2372236T3 (enExample) |
| HK (1) | HK1213295A1 (enExample) |
| HR (1) | HRP20110867T1 (enExample) |
| IL (1) | IL205748A0 (enExample) |
| MX (2) | MX340668B (enExample) |
| NZ (1) | NZ628598A (enExample) |
| PL (1) | PL2220492T3 (enExample) |
| PT (1) | PT2220492E (enExample) |
| RS (1) | RS51987B (enExample) |
| RU (2) | RU2482491C2 (enExample) |
| WO (1) | WO2009073540A2 (enExample) |
| ZA (1) | ZA201003419B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ598791A (en) | 2009-10-23 | 2014-05-30 | Millennium Pharm Inc | Anti-gcc antibody molecules and related compositions and methods |
| WO2011146406A1 (en) * | 2010-05-17 | 2011-11-24 | University Of Southern California | Germline polymorphisms in vegf predict clinical outcomes in cancer patients treated with sorafenib |
| BR112013001423A2 (pt) * | 2010-07-19 | 2016-05-24 | Hoffmann La Roche | método, método in vitro, uso e kit útil para realizar o método |
| AR085301A1 (es) * | 2011-02-23 | 2013-09-18 | Sanofi Sa | Polimorfismos de un solo nucleotido en el promotor del gen vegfa y su uso como marcadores predictivos para tratamientos anti-vegf |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| MX2014002311A (es) * | 2011-08-31 | 2014-08-26 | Hoffmann La Roche | Capacidad de respuesta a inhibidores de angiogenesis. |
| EP2751280B1 (en) * | 2011-08-31 | 2016-06-29 | F.Hoffmann-La Roche Ag | Method for predicting risk of hypertension associated with anti-angiogenesis therapy |
| UA117910C2 (uk) * | 2012-04-27 | 2018-10-25 | Мілленніум Фармасьютікалз, Інк. | Молекула анти-gcc антитіла і її використання для тестування на чутливість до gcc-націленої терапії |
| US10456470B2 (en) * | 2013-08-30 | 2019-10-29 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| CN111926080B (zh) | 2014-06-18 | 2024-07-12 | 东丽株式会社 | 肺癌的检测试剂盒或装置以及检测方法 |
| ES2732925T3 (es) | 2014-07-18 | 2019-11-26 | Sanofi Sa | Método para predecir el resultado de un tratamiento con aflibercept de un paciente que se sospecha que padece un cáncer |
| BR112017016307B1 (pt) * | 2015-01-29 | 2024-02-15 | Huawei Technologies Co., Ltd | Método de reconfiguração de portador de rádio e equipamento de usuário |
| EP4520842A3 (en) * | 2018-05-18 | 2025-09-10 | Anavex Life Sciences Corp. | Optimized sigma-1 agonist method of responder selection and treatment |
| CN108913772B (zh) * | 2018-06-15 | 2020-04-03 | 上海思路迪生物医学科技有限公司 | 基于捕获测序的bMSI检测技术 |
| GR1009959B (el) * | 2019-06-21 | 2021-03-18 | ΕΝΟΡΑΣΙΣ ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΚΑΙ ΙΑΤΡΙΚΩΝ ΥΛΙΚΩΝ ΚΑΙ ΜΗΧΑΝΗΜΑΤΩΝ με δ.τ. "ΕΝΟΡΑΣΙΣ Α.Ε." | Οι πολυμορφισμοι σαν προβλεπτικοι παραγοντες στην ανταποκριση στη θεραπεια και τη συνολικη επιβιωση |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8311018D0 (en) | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4998617A (en) | 1986-09-15 | 1991-03-12 | Laura Lupton Inc | Facial cosmetic liquid make up kit |
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
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