BRPI0811536A8 - detecção de sucinilacetona - Google Patents

detecção de sucinilacetona Download PDF

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Publication number
BRPI0811536A8
BRPI0811536A8 BRPI0811536A BRPI0811536A BRPI0811536A8 BR PI0811536 A8 BRPI0811536 A8 BR PI0811536A8 BR PI0811536 A BRPI0811536 A BR PI0811536A BR PI0811536 A BRPI0811536 A BR PI0811536A BR PI0811536 A8 BRPI0811536 A8 BR PI0811536A8
Authority
BR
Brazil
Prior art keywords
sample
mass spectrometry
sucinylacetone
detection
hydrazine
Prior art date
Application number
BRPI0811536A
Other languages
English (en)
Inventor
Cherkasskiy Alex
Cerda Blas
La Marca Giancarlo
Li Yijun
Original Assignee
Azienda Ospedaliero Univ Meyer Di Firenze
Perkinelmer Health Sci Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39939802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0811536(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Azienda Ospedaliero Univ Meyer Di Firenze, Perkinelmer Health Sci Inc filed Critical Azienda Ospedaliero Univ Meyer Di Firenze
Priority to BR122019018448A priority Critical patent/BR122019018448B8/pt
Publication of BRPI0811536A2 publication Critical patent/BRPI0811536A2/pt
Publication of BRPI0811536A8 publication Critical patent/BRPI0811536A8/pt
Publication of BRPI0811536B1 publication Critical patent/BRPI0811536B1/pt
Publication of BRPI0811536B8 publication Critical patent/BRPI0811536B8/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Luminescent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Saccharide Compounds (AREA)

Abstract

"detecção de succinilacetona". a presente invenção refere-se, entre outras coisas, à detecção e/ou medição de succinilacetona e um ou mais analitos biológicos adicionais usando espectrometria de massa.
BRPI0811536A 2007-05-04 2008-05-05 método para detectar uma cetona biologicamente ativa e método para extração BRPI0811536B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/744,789 2007-05-04
US11/744,789 US7951608B2 (en) 2007-05-04 2007-05-04 Detecting succinylacetone
PCT/US2008/062694 WO2008137868A1 (en) 2007-05-04 2008-05-05 Detecting succinylacetone

Publications (4)

Publication Number Publication Date
BRPI0811536A2 BRPI0811536A2 (pt) 2014-11-18
BRPI0811536A8 true BRPI0811536A8 (pt) 2019-10-15
BRPI0811536B1 BRPI0811536B1 (pt) 2020-08-11
BRPI0811536B8 BRPI0811536B8 (pt) 2021-07-27

Family

ID=39939802

Family Applications (2)

Application Number Title Priority Date Filing Date
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais
BRPI0811536A BRPI0811536B8 (pt) 2007-05-04 2008-05-05 método para detectar uma cetona biologicamente ativa e método para extração

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais

Country Status (10)

Country Link
US (3) US7951608B2 (pt)
EP (1) EP2155185B2 (pt)
CN (1) CN101742995B (pt)
AT (1) ATE551055T1 (pt)
AU (1) AU2008247428C1 (pt)
BR (2) BR122019018448B8 (pt)
CA (1) CA2686202C (pt)
DK (1) DK2155185T4 (pt)
ES (1) ES2384288T5 (pt)
WO (1) WO2008137868A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010091264A2 (en) * 2009-02-06 2010-08-12 Perkinelmer Health Sciences, Inc. Simultaneous detection of estrogen and non estrogen steroids
GB201215924D0 (en) * 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
DK2926139T3 (en) * 2012-12-03 2018-10-22 Statens Seruminstitut PROCEDURE FOR DIAGNOSTIZING GALACTOSEMIA IN A NEONATAL SCREENING
CN105659092B (zh) * 2013-10-22 2018-05-25 豪夫迈·罗氏有限公司 测量干血斑中无细胞病毒颗粒的方法
CN105572233A (zh) * 2014-11-18 2016-05-11 湖南农业大学 植物叶片中琥珀酰丙酮的检测方法
WO2018174858A1 (en) * 2017-03-21 2018-09-27 Mprobe Inc. Clinical method for the population screening of adult metabolic disorder associated with chronic human disease
CN108008031A (zh) * 2017-11-17 2018-05-08 深圳华大生命科学研究院 同时检测氨基酸、肉碱、酮类、激素的方法和试剂盒
CN108051494A (zh) * 2017-11-17 2018-05-18 深圳华大生命科学研究院 一种同时检测多种遗传代谢疾病相关物质的方法和试剂盒
CN110568088A (zh) * 2019-05-22 2019-12-13 广州金域医学检验中心有限公司 琥珀酰丙酮的检测方法
CN113030326B (zh) * 2021-03-12 2023-03-10 杭州度安医学检验实验室有限公司 一种用于分离柠檬酸和异柠檬酸的衍生试剂盒和方法
US20220395767A1 (en) * 2021-06-15 2022-12-15 Perkinelmer Health Sciences, Inc. Enhancing lcms analyte signals
CN114965786B (zh) * 2022-06-07 2023-11-03 重庆医科大学附属儿童医院 一种检测干血斑中酯类胆固醇多种中间代谢产物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2488584C (en) * 2003-01-30 2011-10-11 Applera Corporation Methods, mixtures, kits and compositions pertaining to analyte determination
US7906520B2 (en) * 2003-11-13 2011-03-15 The General Hospital Corporation Methods for treating pain
US20070004045A1 (en) * 2005-06-07 2007-01-04 Xia Xu Analysis of large numbers of estrogens and other steroids and applications thereof

Also Published As

Publication number Publication date
ATE551055T1 (de) 2012-04-15
AU2008247428B2 (en) 2014-07-03
AU2008247428C1 (en) 2015-01-29
BRPI0811536A2 (pt) 2014-11-18
CN101742995A (zh) 2010-06-16
CN101742995B (zh) 2013-08-14
BR122019018448B8 (pt) 2021-07-27
EP2155185A4 (en) 2010-11-24
DK2155185T4 (da) 2022-02-07
US20080274563A1 (en) 2008-11-06
ES2384288T5 (es) 2022-05-26
CA2686202A1 (en) 2008-11-13
US8513025B2 (en) 2013-08-20
DK2155185T3 (da) 2012-07-16
US7951608B2 (en) 2011-05-31
WO2008137868A1 (en) 2008-11-13
AU2008247428A1 (en) 2008-11-13
BRPI0811536B8 (pt) 2021-07-27
EP2155185B2 (en) 2021-12-01
US8278116B2 (en) 2012-10-02
US20110201539A1 (en) 2011-08-18
EP2155185A1 (en) 2010-02-24
CA2686202C (en) 2017-07-04
EP2155185B1 (en) 2012-03-28
BR122019018448B1 (pt) 2020-06-30
ES2384288T3 (es) 2012-07-03
US20120309096A1 (en) 2012-12-06
BRPI0811536B1 (pt) 2020-08-11

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B25A Requested transfer of rights approved

Owner name: PERKINELMER HEALTH SCIENCES, INC. (US) , AZIENDA O

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/08/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/05/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B22B Petition not considered [chapter 22.2 patent gazette]

Free format text: NAO CONHECIDA A PETICAO NO 70210088831, DE 27/09/2021, EM VIRTUDE DO DISPOSTO NO ART. 219 , INCISO II DA LPI