BRPI0811536A2 - Detecção de sucinilacetona - Google Patents

Detecção de sucinilacetona

Info

Publication number
BRPI0811536A2
BRPI0811536A2 BRPI0811536-2A2A BRPI0811536A BRPI0811536A2 BR PI0811536 A2 BRPI0811536 A2 BR PI0811536A2 BR PI0811536 A BRPI0811536 A BR PI0811536A BR PI0811536 A2 BRPI0811536 A2 BR PI0811536A2
Authority
BR
Brazil
Prior art keywords
sample
mass spectrometry
synucinethone
detection
hydrazine
Prior art date
Application number
BRPI0811536-2A2A
Other languages
English (en)
Inventor
Blas Cerda
Alex Cherkasskiy
Yijun Li
Original Assignee
Perkinelmer Health Sci Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39939802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0811536(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Perkinelmer Health Sci Inc filed Critical Perkinelmer Health Sci Inc
Priority to BR122019018448A priority Critical patent/BR122019018448B8/pt
Publication of BRPI0811536A2 publication Critical patent/BRPI0811536A2/pt
Publication of BRPI0811536A8 publication Critical patent/BRPI0811536A8/pt
Publication of BRPI0811536B1 publication Critical patent/BRPI0811536B1/pt
Publication of BRPI0811536B8 publication Critical patent/BRPI0811536B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Luminescent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
BRPI0811536A 2007-05-04 2008-05-05 método para detectar uma cetona biologicamente ativa e método para extração BRPI0811536B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/744,789 2007-05-04
US11/744,789 US7951608B2 (en) 2007-05-04 2007-05-04 Detecting succinylacetone
PCT/US2008/062694 WO2008137868A1 (en) 2007-05-04 2008-05-05 Detecting succinylacetone

Publications (4)

Publication Number Publication Date
BRPI0811536A2 true BRPI0811536A2 (pt) 2014-11-18
BRPI0811536A8 BRPI0811536A8 (pt) 2019-10-15
BRPI0811536B1 BRPI0811536B1 (pt) 2020-08-11
BRPI0811536B8 BRPI0811536B8 (pt) 2021-07-27

Family

ID=39939802

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0811536A BRPI0811536B8 (pt) 2007-05-04 2008-05-05 método para detectar uma cetona biologicamente ativa e método para extração
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122019018448A BR122019018448B8 (pt) 2007-05-04 2008-05-05 método para extração de succinilacetona e um ou mais analitos biológicos adicionais

Country Status (10)

Country Link
US (3) US7951608B2 (pt)
EP (1) EP2155185B2 (pt)
CN (1) CN101742995B (pt)
AT (1) ATE551055T1 (pt)
AU (1) AU2008247428C1 (pt)
BR (2) BRPI0811536B8 (pt)
CA (1) CA2686202C (pt)
DK (1) DK2155185T4 (pt)
ES (1) ES2384288T5 (pt)
WO (1) WO2008137868A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227412A1 (en) * 2009-02-06 2010-09-09 Perkinelmer Health Sciences, Inc. Simultaneous Detection of Estrogen and Non Estrogen Steroids
GB201215924D0 (en) * 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
US9410960B2 (en) * 2012-12-03 2016-08-09 Statens Serum Institut Method of diagnosing galactosemia in neonatal screening
ES2705574T3 (es) * 2013-10-22 2019-03-26 Hoffmann La Roche Procedimientos para medir partículas de virus libres de células a partir de gotas de sangre seca
CN105572233A (zh) * 2014-11-18 2016-05-11 湖南农业大学 植物叶片中琥珀酰丙酮的检测方法
WO2018174858A1 (en) * 2017-03-21 2018-09-27 Mprobe Inc. Clinical method for the population screening of adult metabolic disorder associated with chronic human disease
CN108008031A (zh) * 2017-11-17 2018-05-08 深圳华大生命科学研究院 同时检测氨基酸、肉碱、酮类、激素的方法和试剂盒
CN108051494A (zh) * 2017-11-17 2018-05-18 深圳华大生命科学研究院 一种同时检测多种遗传代谢疾病相关物质的方法和试剂盒
CN110568088A (zh) * 2019-05-22 2019-12-13 广州金域医学检验中心有限公司 琥珀酰丙酮的检测方法
CN113030326B (zh) * 2021-03-12 2023-03-10 杭州度安医学检验实验室有限公司 一种用于分离柠檬酸和异柠檬酸的衍生试剂盒和方法
US20220395767A1 (en) * 2021-06-15 2022-12-15 Perkinelmer Health Sciences, Inc. Enhancing lcms analyte signals
CN114965786B (zh) * 2022-06-07 2023-11-03 重庆医科大学附属儿童医院 一种检测干血斑中酯类胆固醇多种中间代谢产物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004209401A1 (en) * 2003-01-30 2004-08-19 Applied Biosystems, Llc. Methods, mixtures, kits and compositions pertaining to analyte determination
EP1696877A4 (en) * 2003-11-13 2010-06-09 Gen Hospital Corp PROCESS FOR PAIN TREATMENT
US20070004045A1 (en) * 2005-06-07 2007-01-04 Xia Xu Analysis of large numbers of estrogens and other steroids and applications thereof

Also Published As

Publication number Publication date
BRPI0811536A8 (pt) 2019-10-15
CA2686202A1 (en) 2008-11-13
CA2686202C (en) 2017-07-04
AU2008247428C1 (en) 2015-01-29
US20080274563A1 (en) 2008-11-06
DK2155185T3 (da) 2012-07-16
CN101742995B (zh) 2013-08-14
BR122019018448B8 (pt) 2021-07-27
BR122019018448B1 (pt) 2020-06-30
AU2008247428B2 (en) 2014-07-03
EP2155185A1 (en) 2010-02-24
EP2155185A4 (en) 2010-11-24
US8513025B2 (en) 2013-08-20
US8278116B2 (en) 2012-10-02
BRPI0811536B8 (pt) 2021-07-27
US7951608B2 (en) 2011-05-31
CN101742995A (zh) 2010-06-16
EP2155185B2 (en) 2021-12-01
ES2384288T5 (es) 2022-05-26
DK2155185T4 (da) 2022-02-07
BRPI0811536B1 (pt) 2020-08-11
US20120309096A1 (en) 2012-12-06
ATE551055T1 (de) 2012-04-15
EP2155185B1 (en) 2012-03-28
US20110201539A1 (en) 2011-08-18
AU2008247428A1 (en) 2008-11-13
ES2384288T3 (es) 2012-07-03
WO2008137868A1 (en) 2008-11-13

Similar Documents

Publication Publication Date Title
BRPI0811536A2 (pt) Detecção de sucinilacetona
DK2132339T3 (da) Fremgangsmåde til detektering af en analyt i en biologisk matrix
MX2020002799A (es) Dispositivo de ensayo biologico multiplexado con lectura electronica.
DE602006011756D1 (de) Komplexformierungs- und -trennungsverfahren
GB2474146A (en) Methods of determining the health status of an individual
WO2008070865A3 (en) Materials and methods for efficient and accurate detection of analytes
ATE538715T1 (de) System zur in vivo analyse
ATE532063T1 (de) Elektrochemischer biosensor
TW200643400A (en) Optical-based sensing devices
AR054900A1 (es) Medidor con alarma de tiempo postprandial para efectuar determinaciones
BRPI0915619A2 (pt) métodos para determinar uma probabilidade de que um sujeito tenha contribuído com material genético para amostra de teste de material genético, para caracterizar amostra de teste de material genético e para determinar se uma pessoa de interesse contribuiu com material genético para uma amostra de teste de material genético, kit para análise de amostra de teste de material genético e sistema para determinar se um sujeito contribuiu com material genético para uma amostra
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
EA201992748A1 (ru) Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов
SE0800724L (sv) Blodviskositetsanalys
ECSP088081A (es) Detección de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapéutico correspondiente
WO2010065781A3 (en) Lateral flow strip assay with immobilized conjugate
EA201101563A1 (ru) Безколбовый спектрометр
WO2008106648A3 (en) Immunoassays exhibiting a reduction in prozone phenomena
WO2009103843A3 (en) Method and device for detection of an analyte
MX2016002632A (es) Dispositivo y metodos para usar un dispositivo para la deteccion de hiperamoniemia.
HK1115636A1 (en) Use of cyfra 21-1 as a marker for colorectal cancer cyfra 21-1
EA201391627A1 (ru) Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения
WO2009099905A3 (en) Molecular signatures and biomarkers associated with melanoma and methods of use thereof
WO2008124091A3 (en) Compositions and methods of detection
WO2011137388A3 (en) Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: PERKINELMER HEALTH SCIENCES, INC. (US) , AZIENDA O

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/08/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/05/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B22B Petition not considered [chapter 22.2 patent gazette]

Free format text: NAO CONHECIDA A PETICAO NO 70210088831, DE 27/09/2021, EM VIRTUDE DO DISPOSTO NO ART. 219 , INCISO II DA LPI