BRPI0810031A2 - Ligantes do receptor vanilóide e seu uso para a fabricação de fármacos - Google Patents

Ligantes do receptor vanilóide e seu uso para a fabricação de fármacos

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Publication number
BRPI0810031A2
BRPI0810031A2 BRPI0810031-4A2A BRPI0810031A BRPI0810031A2 BR PI0810031 A2 BRPI0810031 A2 BR PI0810031A2 BR PI0810031 A BRPI0810031 A BR PI0810031A BR PI0810031 A2 BRPI0810031 A2 BR PI0810031A2
Authority
BR
Brazil
Prior art keywords
vaniloid
pharmaceuticals
manufacture
binds
receiver
Prior art date
Application number
BRPI0810031-4A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Robert Frank
Gregor Bahrenberg
Thomas Christoph
Klaus Schiene
Jean De Vry
Derek Saunders
Michael Przewosny
Jeewoo Lee
Bernd Sundermann
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BRPI0810031A2 publication Critical patent/BRPI0810031A2/pt

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/62—Oxygen or sulfur atoms
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BRPI0810031-4A2A 2007-04-16 2008-04-15 Ligantes do receptor vanilóide e seu uso para a fabricação de fármacos BRPI0810031A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007018151A DE102007018151A1 (de) 2007-04-16 2007-04-16 Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
PCT/EP2008/002994 WO2008125337A2 (de) 2007-04-16 2008-04-15 Neue vanilloid-rezeptor liganden und ihre verwendung zur herstellung von arzneimitteln

Publications (1)

Publication Number Publication Date
BRPI0810031A2 true BRPI0810031A2 (pt) 2014-10-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810031-4A2A BRPI0810031A2 (pt) 2007-04-16 2008-04-15 Ligantes do receptor vanilóide e seu uso para a fabricação de fármacos

Country Status (16)

Country Link
US (2) US8642775B2 (OSRAM)
EP (1) EP2146962A2 (OSRAM)
JP (1) JP5557734B2 (OSRAM)
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CO6220938A2 (es) 2010-11-19
CN101687799A (zh) 2010-03-31
MX2009011139A (es) 2009-10-30
AU2008238245A1 (en) 2008-10-23
EP2146962A2 (de) 2010-01-27
ZA200907096B (en) 2013-03-27
DE102007018151A1 (de) 2008-10-23
WO2008125337A3 (de) 2009-02-26
KR20100016594A (ko) 2010-02-12
CA2683910A1 (en) 2008-04-16
US8642775B2 (en) 2014-02-04
KR101497357B1 (ko) 2015-03-02
WO2008125337A2 (de) 2008-10-23
CN101687799B (zh) 2014-07-23
JP2010523726A (ja) 2010-07-15
JP5557734B2 (ja) 2014-07-23
US20080262039A1 (en) 2008-10-23
RU2487120C2 (ru) 2013-07-10
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RU2009142024A (ru) 2011-05-27
NZ599254A (en) 2013-07-26

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