BRPI0714875A2 - meios para inibir a expressço da proteÍna cinase 3 - Google Patents

meios para inibir a expressço da proteÍna cinase 3 Download PDF

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Publication number
BRPI0714875A2
BRPI0714875A2 BRPI0714875-5A BRPI0714875A BRPI0714875A2 BR PI0714875 A2 BRPI0714875 A2 BR PI0714875A2 BR PI0714875 A BRPI0714875 A BR PI0714875A BR PI0714875 A2 BRPI0714875 A2 BR PI0714875A2
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Brazil
Prior art keywords
seq
nucleotide
extension
nucleotide sequence
nucleic acid
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BRPI0714875-5A
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English (en)
Portuguese (pt)
Inventor
Joerg Kaufmann
Oliver Keil
Ansgar Santel
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Silence Therapeutics Ag
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Publication of BRPI0714875A2 publication Critical patent/BRPI0714875A2/pt

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/3212'-O-R Modification

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BRPI0714875-5A 2006-07-21 2007-07-20 meios para inibir a expressço da proteÍna cinase 3 BRPI0714875A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06015262 2006-07-21
EP06015262.6 2006-07-21
PCT/EP2007/006492 WO2008009477A2 (en) 2006-07-21 2007-07-20 Means for inhibiting the expression of protein kinase 3

Publications (1)

Publication Number Publication Date
BRPI0714875A2 true BRPI0714875A2 (pt) 2013-05-28

Family

ID=38663298

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0714875-5A BRPI0714875A2 (pt) 2006-07-21 2007-07-20 meios para inibir a expressço da proteÍna cinase 3

Country Status (12)

Country Link
US (1) US8232256B2 (enExample)
EP (2) EP2546337A1 (enExample)
JP (3) JP2009544281A (enExample)
KR (1) KR101670085B1 (enExample)
CN (3) CN101490253A (enExample)
AU (1) AU2007276388A1 (enExample)
BR (1) BRPI0714875A2 (enExample)
CA (1) CA2658550C (enExample)
HK (1) HK1208701A1 (enExample)
MX (1) MX2009000654A (enExample)
RU (1) RU2553561C2 (enExample)
WO (1) WO2008009477A2 (enExample)

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KR101670085B1 (ko) 2006-07-21 2016-10-28 사일런스 테라퓨틱스 게엠베하 단백질 키나아제 3의 발현을 억제하기 위한 수단
WO2010110314A1 (ja) * 2009-03-27 2010-09-30 協和発酵キリン株式会社 核酸を含有する肺高血圧症治療剤
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KR20090039715A (ko) 2009-04-22
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KR101670085B1 (ko) 2016-10-28
WO2008009477A3 (en) 2008-05-29
CN104531701A (zh) 2015-04-22
US8232256B2 (en) 2012-07-31
AU2007276388A1 (en) 2008-01-24
CA2658550C (en) 2018-06-19
JP2013172714A (ja) 2013-09-05
RU2553561C2 (ru) 2015-06-20
CN101490253A (zh) 2009-07-22
RU2009106071A (ru) 2010-08-27
CA2658550A1 (en) 2008-01-24
JP2009544281A (ja) 2009-12-17
CN102321626A (zh) 2012-01-18
WO2008009477A2 (en) 2008-01-24
US20090304678A1 (en) 2009-12-10
CN102321626B (zh) 2014-12-10
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EP2546337A1 (en) 2013-01-16
HK1208701A1 (en) 2016-03-11

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