AU2001264317A1 - Preparations for oligonucleotide transfer - Google Patents
Preparations for oligonucleotide transferInfo
- Publication number
- AU2001264317A1 AU2001264317A1 AU2001264317A AU6431701A AU2001264317A1 AU 2001264317 A1 AU2001264317 A1 AU 2001264317A1 AU 2001264317 A AU2001264317 A AU 2001264317A AU 6431701 A AU6431701 A AU 6431701A AU 2001264317 A1 AU2001264317 A1 AU 2001264317A1
- Authority
- AU
- Australia
- Prior art keywords
- preparations
- oligonucleotide transfer
- oligonucleotide
- transfer
- collagen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Abstract
Preparations for transferring efficiently oligonucleotides necessary in antisense therapy or the like into animal cells so as to be useful in treatment for various diseases, which comprises a collagen as an essential component are provided.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000-184502 | 2000-06-20 | ||
JP2000184502 | 2000-06-20 | ||
PCT/JP2001/005195 WO2001097857A1 (en) | 2000-06-20 | 2001-06-19 | Preparations for oligonucleotide transfer |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001264317A1 true AU2001264317A1 (en) | 2002-01-02 |
Family
ID=18684937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001264317A Abandoned AU2001264317A1 (en) | 2000-06-20 | 2001-06-19 | Preparations for oligonucleotide transfer |
Country Status (10)
Country | Link |
---|---|
US (3) | US20040052840A1 (en) |
EP (1) | EP1295611B1 (en) |
JP (1) | JP5118285B2 (en) |
AT (1) | ATE478688T1 (en) |
AU (1) | AU2001264317A1 (en) |
DE (1) | DE60142899D1 (en) |
DK (1) | DK1295611T3 (en) |
ES (1) | ES2349137T3 (en) |
PT (1) | PT1295611E (en) |
WO (1) | WO2001097857A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
AU2001264317A1 (en) * | 2000-06-20 | 2002-01-02 | Koken Co., Ltd. | Preparations for oligonucleotide transfer |
DK1407787T3 (en) * | 2001-06-20 | 2009-06-02 | Dainippon Sumitomo Pharma Co | Process for promoting nucleic acid transfer |
US20100104631A1 (en) * | 2001-08-13 | 2010-04-29 | Lipella Pharmaceuticals Inc. | Method of treatment for bladder dysfunction |
AU2003264507A1 (en) * | 2002-09-20 | 2004-04-08 | Koken Co., Ltd. | Site-specific gene conversion promoter and gene therapeutic |
JP4954550B2 (en) * | 2003-12-19 | 2012-06-20 | 大日本住友製薬株式会社 | Novel nucleic acid introduction method |
US20090062184A1 (en) * | 2005-03-24 | 2009-03-05 | Dainippon Sumitomo Pharma Co., Ltd. | Fine particulate preparation comprising complex of nucleic acid molecule and collagen |
US7838502B2 (en) * | 2005-05-06 | 2010-11-23 | University Of Massachusetts Medical School | Compositions and methods to modulate H. influenzae pathogenesis |
ES2405357T3 (en) * | 2005-05-25 | 2013-05-30 | Cellmid Limited | Pharmaceutical composition for occlusive vasculopathy. |
KR100777249B1 (en) * | 2006-02-14 | 2007-11-28 | (주)바이오니아 | Dried Oligonucleotide Composition and Method of Producing the Same |
WO2010078403A2 (en) * | 2008-12-30 | 2010-07-08 | Lipella Pharmaceuticals Inc. | Methods and compositions for diagnosing urological disorders |
FR3066115B1 (en) * | 2017-05-10 | 2019-06-28 | Universite de Bordeaux | COMPRESSES OF NUCLEIC ACID VECTORS |
Family Cites Families (54)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS5115094B2 (en) * | 1972-11-01 | 1976-05-14 | ||
US5069936A (en) * | 1987-06-25 | 1991-12-03 | Yen Richard C K | Manufacturing protein microspheres |
US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
US5098890A (en) * | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
US5936035A (en) * | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
US5614587A (en) * | 1988-11-21 | 1997-03-25 | Collagen Corporation | Collagen-based bioadhesive compositions |
JP3187410B2 (en) * | 1989-08-10 | 2001-07-11 | 住友製薬株式会社 | Sustained release formulation for intracerebral administration |
US5542935A (en) * | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
FR2694895B1 (en) * | 1992-08-20 | 1994-11-10 | Coletica | Process for the production of emulsion microparticles by modification of the chemical composition of the dispersed phase after emulsification. |
US5646042A (en) * | 1992-08-26 | 1997-07-08 | Ribozyme Pharmaceuticals, Inc. | C-myb targeted ribozymes |
EP0745092B1 (en) * | 1993-05-28 | 1999-07-21 | Chiron Corporation | Peptide inhibitors of urokinase receptor activity |
KR960704526A (en) * | 1993-09-09 | 1996-10-09 | 베. 클로제·우베 하르트만 | Active Principles and Gas Containing Microparticles |
CA2140053C (en) * | 1994-02-09 | 2000-04-04 | Joel S. Rosenblatt | Collagen-based injectable drug delivery system and its use |
US5942496A (en) * | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
US5583034A (en) * | 1994-02-22 | 1996-12-10 | La Jolla Institute For Allergy And Immunology | Enhancement of adoptosis using antisense oligonucleotides |
US5844107A (en) * | 1994-03-23 | 1998-12-01 | Case Western Reserve University | Compacted nucleic acids and their delivery to cells |
US5563255A (en) * | 1994-05-31 | 1996-10-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of raf gene expression |
AU2946295A (en) * | 1994-06-27 | 1996-01-19 | Johns Hopkins University, The | Targeted gene delivery system |
WO2001074342A2 (en) * | 2000-03-31 | 2001-10-11 | Trustees Of Boston University | Use of locally applied dna fragments |
EP0844004B1 (en) * | 1995-07-03 | 2007-09-12 | Koken Co., Ltd. | Collagen containing gene preparations |
US6998268B2 (en) * | 1995-07-03 | 2006-02-14 | Dainippon Sumitomo Pharma Co. Ltd. | Gene preparations |
JP3867160B2 (en) * | 1995-07-03 | 2007-01-10 | 大日本住友製薬株式会社 | Gene preparation |
KR19990066967A (en) * | 1995-10-23 | 1999-08-16 | 둘헌티 브리안 | Gene therapy for treating abnormal retinal angiogenesis and hyaluronic acid used as a DNA carrier for VEGF antisense |
PT876165E (en) * | 1995-12-18 | 2006-10-31 | Angiotech Biomaterials Corp | COMPOSITIONS OF RETICULATED POLYMERS AND PROCESSES FOR THEIR USE |
AU728146B2 (en) * | 1996-03-14 | 2001-01-04 | Immune Response Corporation, The | Targeted delivery of genes encoding interferon |
US6133437A (en) * | 1997-02-13 | 2000-10-17 | Apoptogen, Inc. | Modulation of IAPs for the treatment of proliferative diseases |
US5874006A (en) * | 1996-10-31 | 1999-02-23 | Matrix Pharmaceutical, Inc. | Aseptic collagen concentration process |
US6042820A (en) * | 1996-12-20 | 2000-03-28 | Connaught Laboratories Limited | Biodegradable copolymer containing α-hydroxy acid and α-amino acid units |
US6218112B1 (en) * | 1996-12-23 | 2001-04-17 | Cobra Therapeutics Limited | Optimization of gene delivery and gene delivery system |
WO1998030575A1 (en) * | 1997-01-08 | 1998-07-16 | Proligo Llc | Bioconjugation of macromolecules |
US6524613B1 (en) * | 1997-04-30 | 2003-02-25 | Regents Of The University Of Minnesota | Hepatocellular chimeraplasty |
EP1054694A2 (en) * | 1998-02-13 | 2000-11-29 | Selective Genetics, Inc. | Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby |
EP1078639A4 (en) * | 1998-05-22 | 2004-10-06 | Sumitomo Pharma | Stable gene preparations |
AU2001264317A1 (en) * | 2000-06-20 | 2002-01-02 | Koken Co., Ltd. | Preparations for oligonucleotide transfer |
JP2002325572A (en) * | 2000-12-25 | 2002-11-12 | Univ Osaka | Method for introducing exogenous substance |
DK1407787T3 (en) * | 2001-06-20 | 2009-06-02 | Dainippon Sumitomo Pharma Co | Process for promoting nucleic acid transfer |
US7148342B2 (en) * | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
US20060030534A1 (en) * | 2002-09-04 | 2006-02-09 | Gabriele Dorn | Treatment of neurological disorders by dsrna administration |
AU2003264507A1 (en) * | 2002-09-20 | 2004-04-08 | Koken Co., Ltd. | Site-specific gene conversion promoter and gene therapeutic |
US7521431B2 (en) * | 2002-11-01 | 2009-04-21 | The Trustees Of The University Of Pennsylvania | Compositions and methods for siRNA inhibition of HIF-1 alpha |
MXPA05007651A (en) * | 2003-01-16 | 2005-10-26 | Univ Pennsylvania | COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ICAM-1. |
US8227434B1 (en) * | 2003-11-04 | 2012-07-24 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Materials and methods for treating oncological disorders |
ES2523147T3 (en) * | 2004-02-26 | 2014-11-21 | Baylor Research Institute | Compositions and methods for the systemic treatment of arthritis |
JP4991547B2 (en) * | 2004-09-28 | 2012-08-01 | クアーク・ファーマスーティカルス、インコーポレイテッド | Oligoribonucleotides and methods of use thereof for the treatment of alopecia, acute renal failure and other diseases |
CN101060863B (en) * | 2004-10-22 | 2012-06-06 | 拉瓦勒大学 | Modulation of neuroglia-derived BDNF in the treatment and prevention of pain |
US7585848B2 (en) * | 2005-01-11 | 2009-09-08 | Rush University Medical Center | Methods and compositions for treating, inhibiting and reversing disorders of the intervertebral disc |
EP1983823A1 (en) * | 2006-01-17 | 2008-10-29 | VIB vzw | Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration |
CA2655355C (en) * | 2006-06-16 | 2014-05-06 | Taisho Pharmaceutical Co., Ltd. | Use of rpn2 gene expression inhibitor |
US8232256B2 (en) * | 2006-07-21 | 2012-07-31 | Silence Therapeutics Ag | Means for inhibiting the expression of protein kinase 3 |
WO2008028085A2 (en) * | 2006-08-30 | 2008-03-06 | The Board Of Trustees Of The University Of Illinois | Modulation of mlck-l expression and uses thereof |
CA2665202A1 (en) * | 2006-10-02 | 2008-04-10 | Aprea Ab | Compounds and methods |
US7812002B2 (en) * | 2007-03-21 | 2010-10-12 | Quark Pharmaceuticals, Inc. | Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer |
WO2011069155A1 (en) * | 2009-12-04 | 2011-06-09 | Opko Ophthalmics, Llc | Compositions and methods for inhibition of vegf |
-
2001
- 2001-06-19 AU AU2001264317A patent/AU2001264317A1/en not_active Abandoned
- 2001-06-19 US US10/311,621 patent/US20040052840A1/en not_active Abandoned
- 2001-06-19 AT AT01938732T patent/ATE478688T1/en active
- 2001-06-19 DE DE60142899T patent/DE60142899D1/en not_active Expired - Lifetime
- 2001-06-19 JP JP2002503340A patent/JP5118285B2/en not_active Expired - Fee Related
- 2001-06-19 EP EP01938732A patent/EP1295611B1/en not_active Expired - Lifetime
- 2001-06-19 WO PCT/JP2001/005195 patent/WO2001097857A1/en active Application Filing
- 2001-06-19 DK DK01938732.3T patent/DK1295611T3/en active
- 2001-06-19 ES ES01938732T patent/ES2349137T3/en not_active Expired - Lifetime
- 2001-06-19 PT PT01938732T patent/PT1295611E/en unknown
-
2009
- 2009-06-17 US US12/486,703 patent/US20090258933A1/en not_active Abandoned
-
2010
- 2010-10-13 US US12/904,054 patent/US20110028535A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1295611A4 (en) | 2009-07-08 |
DE60142899D1 (en) | 2010-10-07 |
EP1295611B1 (en) | 2010-08-25 |
PT1295611E (en) | 2010-09-14 |
US20110028535A1 (en) | 2011-02-03 |
DK1295611T3 (en) | 2010-10-04 |
US20040052840A1 (en) | 2004-03-18 |
EP1295611A1 (en) | 2003-03-26 |
US20090258933A1 (en) | 2009-10-15 |
ATE478688T1 (en) | 2010-09-15 |
JP5118285B2 (en) | 2013-01-16 |
ES2349137T3 (en) | 2010-12-28 |
WO2001097857A1 (en) | 2001-12-27 |
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