BRPI0713484A2 - expressão diferencial de citocina em cáncer humano - Google Patents
expressão diferencial de citocina em cáncer humano Download PDFInfo
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- BRPI0713484A2 BRPI0713484A2 BRPI0713484-3A BRPI0713484A BRPI0713484A2 BR PI0713484 A2 BRPI0713484 A2 BR PI0713484A2 BR PI0713484 A BRPI0713484 A BR PI0713484A BR PI0713484 A2 BRPI0713484 A2 BR PI0713484A2
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
Landscapes
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- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
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| EP06012754 | 2006-06-21 | ||
| EP06012754.5 | 2006-06-21 | ||
| PCT/EP2007/005480 WO2007147600A2 (en) | 2006-06-21 | 2007-06-21 | Differential il-4 and/or il-10 cytokine expression in human cancer |
Publications (1)
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| BRPI0713484A2 true BRPI0713484A2 (pt) | 2012-11-06 |
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| BRPI0713484-3A BRPI0713484A2 (pt) | 2006-06-21 | 2007-06-21 | expressão diferencial de citocina em cáncer humano |
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| EP (1) | EP2041576B1 (enExample) |
| JP (1) | JP2010514409A (enExample) |
| CN (1) | CN101529253A (enExample) |
| AT (1) | ATE520032T1 (enExample) |
| AU (1) | AU2007263265A1 (enExample) |
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| ES (1) | ES2371287T3 (enExample) |
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| WO (1) | WO2007147600A2 (enExample) |
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| US20100297110A1 (en) * | 2006-03-22 | 2010-11-25 | Apogenix Gmbh | Antibody specific for human il-4 for the treatment of cancer |
| CA2656135A1 (en) * | 2006-07-06 | 2008-01-10 | Apogenix Gmbh | Human il-4 muteins in cancer therapy |
| CA2878992C (en) * | 2012-07-18 | 2020-09-22 | Apogenix Gmbh | Composition comprising a mixture of cd95-fc isoforms |
| US11299528B2 (en) | 2014-03-11 | 2022-04-12 | D&D Pharmatech Inc. | Long acting TRAIL receptor agonists for treatment of autoimmune diseases |
| ES2841075T3 (es) * | 2014-10-24 | 2021-07-07 | Calidi Biotherapeutics Inc | Enfoque de inmunoterapia de combinación para el tratamiento del cáncer |
| JP6788663B2 (ja) | 2015-08-11 | 2020-11-25 | カリディ・バイオセラピューティクス・インコーポレイテッドＣａｌｉｄｉ Ｂｉｏｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 癌処置のための天然痘ワクチン |
| CN108601819B (zh) | 2015-12-17 | 2022-03-15 | 约翰霍普金斯大学 | 用死亡受体激动剂改善系统性硬化症 |
| JP7281795B2 (ja) | 2016-04-07 | 2023-05-26 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 膵炎および疼痛をデス受容体アゴニストで処置するための組成物および方法 |
| EP4053557A1 (en) * | 2016-11-24 | 2022-09-07 | Huvet Bio, Inc. | Il-29 as a marker for a pancreatic disease |
| CN111051349A (zh) * | 2017-09-06 | 2020-04-21 | 弗雷德哈钦森癌症研究中心 | Strep-tag特异性嵌合受体及其用途 |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
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| AU643427B2 (en) * | 1988-10-31 | 1993-11-18 | Immunex Corporation | Interleukin-4 receptors |
| DE4137333A1 (de) * | 1991-11-13 | 1993-05-19 | W Prof Dr Sebald | Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung |
| US6534051B1 (en) * | 1992-11-20 | 2003-03-18 | University Of Medicine And Dentistry Of New Jersey | Cell type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins and wild-type envelope fusion proteins |
| HU222041B1 (hu) | 1993-09-07 | 2003-04-28 | Smithkline Beecham Corporation | Az IL4 által kőzvetített rendellenességek kezelésére használható rekombináns 1L4 antitestek, eljárás ezek előállítására, alkalmazására és az őket tartalmazó gyógyszerkészítmények |
| DE4423131A1 (de) * | 1994-07-01 | 1996-01-04 | Bayer Ag | Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4 |
| CZ1497A3 (en) * | 1994-07-05 | 1997-05-14 | Steeno Res Group As | Polypeptide, its use and pharmaceutical composition based thereon, a nucleotide sequence and antibody |
| JPH10503371A (ja) * | 1994-07-29 | 1998-03-31 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 新規化合物 |
| US5710023A (en) * | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| US6664227B1 (en) * | 1996-03-01 | 2003-12-16 | Genetics Institute, Llc | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| US20030124125A1 (en) * | 1996-04-05 | 2003-07-03 | South Alabama Medical Science Foundation | Oncofetal antigen specific T-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10 |
| US6028176A (en) * | 1996-07-19 | 2000-02-22 | Bayer Corporation | High-affinity interleukin-4 muteins |
| CA2309598A1 (en) * | 1997-11-10 | 1999-05-20 | Mochida Pharmaceutical Co., Ltd. | Preventives and remedies for diffuse lung disease |
| JPH11312463A (ja) * | 1998-04-28 | 1999-11-09 | Hitachi Ltd | 配線基板およびそれを用いたガス放電型表示装置 |
| KR20020091170A (ko) * | 2000-03-31 | 2002-12-05 | 아이덱 파마슈티칼즈 코포레이션 | Ｂ 세포 림프종의 치료를 위한 항-사이토카인 항체 또는길항제 및 항-ｃｄ２０의 조합된 사용 |
| US20020076409A1 (en) * | 2000-07-12 | 2002-06-20 | March Carl J. | Method for treating cancer |
| US20040023338A1 (en) * | 2001-10-26 | 2004-02-05 | Heavner George A. | IL-4 mutein proteins, antibodies, compositions, methods and uses |
| WO2003035847A2 (en) * | 2001-10-26 | 2003-05-01 | Centocor, Inc. | Il-13 mutein proteins, antibodies, compositions, methods and uses |
| EP1444989A1 (en) * | 2003-02-07 | 2004-08-11 | Giorgio Dr. Stassi | Sensitizing cells for apoptosis by selectively blocking cytokines |
| AR049390A1 (es) * | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| US7501121B2 (en) * | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| EP1824886B1 (en) * | 2004-11-17 | 2010-12-22 | Amgen Inc. | Fully human monoclonal antibodies to il-13 |
| US20070122855A1 (en) * | 2005-11-28 | 2007-05-31 | Targetgen Inc. | Methods for diagnosing hepatocellular carcinoma |
| US20100297110A1 (en) * | 2006-03-22 | 2010-11-25 | Apogenix Gmbh | Antibody specific for human il-4 for the treatment of cancer |
| CA2656135A1 (en) * | 2006-07-06 | 2008-01-10 | Apogenix Gmbh | Human il-4 muteins in cancer therapy |
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2007
- 2007-06-21 AT AT07764767T patent/ATE520032T1/de not_active IP Right Cessation
- 2007-06-21 DK DK07764767.5T patent/DK2041576T3/da active
- 2007-06-21 CN CNA2007800295788A patent/CN101529253A/zh active Pending
- 2007-06-21 WO PCT/EP2007/005480 patent/WO2007147600A2/en not_active Ceased
- 2007-06-21 ES ES07764767T patent/ES2371287T3/es active Active
- 2007-06-21 BR BRPI0713484-3A patent/BRPI0713484A2/pt not_active IP Right Cessation
- 2007-06-21 AU AU2007263265A patent/AU2007263265A1/en not_active Abandoned
- 2007-06-21 RU RU2009101783/15A patent/RU2009101783A/ru not_active Application Discontinuation
- 2007-06-21 CA CA002656379A patent/CA2656379A1/en not_active Abandoned
- 2007-06-21 EP EP07764767A patent/EP2041576B1/en active Active
- 2007-06-21 JP JP2009515770A patent/JP2010514409A/ja active Pending
- 2007-06-21 US US12/306,070 patent/US20090324616A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101529253A (zh) | 2009-09-09 |
| RU2009101783A (ru) | 2010-07-27 |
| US20090324616A1 (en) | 2009-12-31 |
| EP2041576A2 (en) | 2009-04-01 |
| ES2371287T3 (es) | 2011-12-29 |
| CA2656379A1 (en) | 2007-12-27 |
| EP2041576B1 (en) | 2011-08-10 |
| AU2007263265A1 (en) | 2007-12-27 |
| WO2007147600A3 (en) | 2008-04-10 |
| JP2010514409A (ja) | 2010-05-06 |
| DK2041576T3 (da) | 2011-12-05 |
| WO2007147600A2 (en) | 2007-12-27 |
| ATE520032T1 (de) | 2011-08-15 |
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