CA2656379A1 - Differential cytokine expression in human cancer - Google Patents
Differential cytokine expression in human cancer Download PDFInfo
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- CA2656379A1 CA2656379A1 CA002656379A CA2656379A CA2656379A1 CA 2656379 A1 CA2656379 A1 CA 2656379A1 CA 002656379 A CA002656379 A CA 002656379A CA 2656379 A CA2656379 A CA 2656379A CA 2656379 A1 CA2656379 A1 CA 2656379A1
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| EP06012754.5 | 2006-06-21 | ||
| EP06012754 | 2006-06-21 | ||
| PCT/EP2007/005480 WO2007147600A2 (en) | 2006-06-21 | 2007-06-21 | Differential il-4 and/or il-10 cytokine expression in human cancer |
Publications (1)
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| CA2656379A1 true CA2656379A1 (en) | 2007-12-27 |
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| US (1) | US20090324616A1 (enExample) |
| EP (1) | EP2041576B1 (enExample) |
| JP (1) | JP2010514409A (enExample) |
| CN (1) | CN101529253A (enExample) |
| AT (1) | ATE520032T1 (enExample) |
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| WO2007107349A1 (en) * | 2006-03-22 | 2007-09-27 | Apogenix Gmbh | Antibody specific for human il-4 for the treament of cancer |
| WO2008003514A2 (en) * | 2006-07-06 | 2008-01-10 | Apogenix Gmbh | Human il-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy |
| RU2648157C2 (ru) * | 2012-07-18 | 2018-03-22 | Аподжиникс Аг | КОМПОЗИЦИЯ, ВКЛЮЧАЮЩАЯ СМЕСЬ ИЗОФОРМ CD95-Fc |
| WO2015138638A1 (en) | 2014-03-11 | 2015-09-17 | Theraly Pharmaceuticals, Inc. | Long acting trail receptor agonists for treatment of autoimmune diseases |
| CA3003133C (en) * | 2014-10-24 | 2020-09-15 | StemImmune, Incorporated | Combination immunotherapy approach for treatment of cancer |
| EA201800148A1 (ru) | 2015-08-11 | 2019-01-31 | Калиди Биотерапьютикс, Инк. | Оспенная вакцина для лечения рака |
| ES3013312T3 (en) | 2015-12-17 | 2025-04-11 | Univ Johns Hopkins | Ameliorating systemic sclerosis with death receptor agonists |
| US11084879B2 (en) | 2016-04-07 | 2021-08-10 | The Johns Hopkins University | Compositions and methods for treating pancreatitis and pain with death receptor agonists |
| US20190317098A1 (en) * | 2016-11-24 | 2019-10-17 | Huvet Bio, Inc. | Composition for diagnosis of diseases |
| US20210023132A1 (en) * | 2017-09-06 | 2021-01-28 | Fred Hutchinson Cancer Research Center | Strep-tag specific chimeric receptors and uses thereof |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
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| WO1990005183A1 (en) | 1988-10-31 | 1990-05-17 | Immunex Corporation | Interleukin-4 receptors |
| DE4137333A1 (de) * | 1991-11-13 | 1993-05-19 | W Prof Dr Sebald | Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung |
| US6534051B1 (en) * | 1992-11-20 | 2003-03-18 | University Of Medicine And Dentistry Of New Jersey | Cell type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins and wild-type envelope fusion proteins |
| BR9407575A (pt) | 1993-09-07 | 1996-07-16 | Smithkline Beecham Corp | Recombinaçao il4 de anticorpos uteis no tratamento de desordens do il4 |
| DE4423131A1 (de) * | 1994-07-01 | 1996-01-04 | Bayer Ag | Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4 |
| CN1216992C (zh) * | 1994-07-05 | 2005-08-31 | 史廷诺研究集团有限公司 | 免疫调节剂 |
| CZ25697A3 (en) | 1994-07-29 | 1997-09-17 | Smithkline Beecham Plc | Novel compounds |
| US6664227B1 (en) * | 1996-03-01 | 2003-12-16 | Genetics Institute, Llc | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| US5710023A (en) * | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| US20030124125A1 (en) * | 1996-04-05 | 2003-07-03 | South Alabama Medical Science Foundation | Oncofetal antigen specific T-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10 |
| US6028176A (en) * | 1996-07-19 | 2000-02-22 | Bayer Corporation | High-affinity interleukin-4 muteins |
| WO1999024069A1 (fr) * | 1997-11-10 | 1999-05-20 | Mochida Pharmaceutical Co., Ltd. | Medicaments preventifs et therapeutiques pour des affections pulmonaires diffuses |
| JPH11312463A (ja) * | 1998-04-28 | 1999-11-09 | Hitachi Ltd | 配線基板およびそれを用いたガス放電型表示装置 |
| CA2404365A1 (en) * | 2000-03-31 | 2001-10-11 | Idec Pharmaceutical Corporation | Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma |
| US20020076409A1 (en) * | 2000-07-12 | 2002-06-20 | March Carl J. | Method for treating cancer |
| US20040023338A1 (en) * | 2001-10-26 | 2004-02-05 | Heavner George A. | IL-4 mutein proteins, antibodies, compositions, methods and uses |
| EP1578912A4 (en) * | 2001-10-26 | 2007-12-26 | Centocor Inc | IL-13 MUTEIN PROTEINS, ANTIBODIES, COMPOSITIONS, METHODS AND USES |
| EP1444989A1 (en) * | 2003-02-07 | 2004-08-11 | Giorgio Dr. Stassi | Sensitizing cells for apoptosis by selectively blocking cytokines |
| US7501121B2 (en) * | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| AR049390A1 (es) * | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| AU2005307831A1 (en) * | 2004-11-17 | 2006-05-26 | Amgen, Inc. | Fully human monoclonal antibodies to IL-13 |
| US20070122855A1 (en) * | 2005-11-28 | 2007-05-31 | Targetgen Inc. | Methods for diagnosing hepatocellular carcinoma |
| WO2007107349A1 (en) * | 2006-03-22 | 2007-09-27 | Apogenix Gmbh | Antibody specific for human il-4 for the treament of cancer |
| WO2008003514A2 (en) * | 2006-07-06 | 2008-01-10 | Apogenix Gmbh | Human il-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy |
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- 2007-06-21 EP EP07764767A patent/EP2041576B1/en active Active
- 2007-06-21 AU AU2007263265A patent/AU2007263265A1/en not_active Abandoned
- 2007-06-21 RU RU2009101783/15A patent/RU2009101783A/ru not_active Application Discontinuation
- 2007-06-21 AT AT07764767T patent/ATE520032T1/de not_active IP Right Cessation
- 2007-06-21 WO PCT/EP2007/005480 patent/WO2007147600A2/en not_active Ceased
- 2007-06-21 CA CA002656379A patent/CA2656379A1/en not_active Abandoned
- 2007-06-21 US US12/306,070 patent/US20090324616A1/en not_active Abandoned
- 2007-06-21 CN CNA2007800295788A patent/CN101529253A/zh active Pending
- 2007-06-21 JP JP2009515770A patent/JP2010514409A/ja active Pending
- 2007-06-21 DK DK07764767.5T patent/DK2041576T3/da active
- 2007-06-21 BR BRPI0713484-3A patent/BRPI0713484A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2009101783A (ru) | 2010-07-27 |
| AU2007263265A1 (en) | 2007-12-27 |
| JP2010514409A (ja) | 2010-05-06 |
| DK2041576T3 (da) | 2011-12-05 |
| EP2041576A2 (en) | 2009-04-01 |
| ES2371287T3 (es) | 2011-12-29 |
| WO2007147600A3 (en) | 2008-04-10 |
| ATE520032T1 (de) | 2011-08-15 |
| BRPI0713484A2 (pt) | 2012-11-06 |
| CN101529253A (zh) | 2009-09-09 |
| US20090324616A1 (en) | 2009-12-31 |
| EP2041576B1 (en) | 2011-08-10 |
| WO2007147600A2 (en) | 2007-12-27 |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20130621 |