BRPI0708291B8 - forma cristalina beta de sal de arginina de perindopril, processo para sua preparação, composições farmacêuticas que a contêm e seus usos - Google Patents
forma cristalina beta de sal de arginina de perindopril, processo para sua preparação, composições farmacêuticas que a contêm e seus usosInfo
- Publication number
- BRPI0708291B8 BRPI0708291B8 BRPI0708291A BRPI0708291A BRPI0708291B8 BR PI0708291 B8 BRPI0708291 B8 BR PI0708291B8 BR PI0708291 A BRPI0708291 A BR PI0708291A BR PI0708291 A BRPI0708291 A BR PI0708291A BR PI0708291 B8 BRPI0708291 B8 BR PI0708291B8
- Authority
- BR
- Brazil
- Prior art keywords
- crystalline form
- arginine salt
- perindopril
- preparation
- beta crystalline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0601747 | 2006-02-28 | ||
FR0601747A FR2897865B1 (fr) | 2006-02-28 | 2006-02-28 | Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
PCT/FR2007/000334 WO2007099216A2 (fr) | 2006-02-28 | 2007-02-26 | FORME CRISTALLINE β DU SEL D'ARGININE DU PERINDOPRIL, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0708291A2 BRPI0708291A2 (pt) | 2011-05-24 |
BRPI0708291B1 BRPI0708291B1 (pt) | 2021-02-02 |
BRPI0708291B8 true BRPI0708291B8 (pt) | 2021-05-25 |
Family
ID=37198804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0708291A BRPI0708291B8 (pt) | 2006-02-28 | 2007-02-26 | forma cristalina beta de sal de arginina de perindopril, processo para sua preparação, composições farmacêuticas que a contêm e seus usos |
Country Status (31)
Country | Link |
---|---|
US (1) | US7923569B2 (pt) |
EP (1) | EP2016051B1 (pt) |
JP (1) | JP5611524B2 (pt) |
KR (1) | KR20080106947A (pt) |
CN (1) | CN101389604B (pt) |
AT (1) | ATE465992T1 (pt) |
AU (1) | AU2007220434B2 (pt) |
BR (1) | BRPI0708291B8 (pt) |
CA (1) | CA2643803C (pt) |
CY (1) | CY1110082T1 (pt) |
DE (1) | DE602007006176D1 (pt) |
DK (1) | DK2016051T3 (pt) |
EA (1) | EA014715B1 (pt) |
ES (1) | ES2345291T3 (pt) |
FR (1) | FR2897865B1 (pt) |
GE (1) | GEP20135839B (pt) |
HK (1) | HK1129668A1 (pt) |
HR (1) | HRP20100357T1 (pt) |
MA (1) | MA30277B1 (pt) |
ME (1) | ME01805B (pt) |
MX (1) | MX2008010747A (pt) |
MY (1) | MY143557A (pt) |
NO (1) | NO341238B1 (pt) |
NZ (1) | NZ570366A (pt) |
PL (1) | PL2016051T3 (pt) |
PT (1) | PT2016051E (pt) |
RS (1) | RS51431B (pt) |
SI (1) | SI2016051T1 (pt) |
UA (1) | UA89904C2 (pt) |
WO (1) | WO2007099216A2 (pt) |
ZA (1) | ZA200807025B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2897866B1 (fr) | 2006-02-28 | 2008-04-18 | Servier Lab | Forme cristalline alpha du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
AU2013245523C1 (en) * | 2008-06-24 | 2017-09-07 | Mylan Laboratories Ltd | Novel polymorphic forms of Perindopril (L)-Arginine and process for the preparation thereof |
CA2729604C (en) * | 2008-06-24 | 2017-12-05 | Matrix Laboratories Ltd. | Polymorphic forms of perindopril (l)-arginine and process for the preparation thereof |
AU2009212902A1 (en) | 2008-09-03 | 2010-03-18 | Apotex Pharmachem Inc. | Amorphous form of an L-arginine salt of perindopril and processes of preparation thereof |
FR2985511B1 (fr) * | 2012-01-05 | 2014-01-03 | Servier Lab | Forme cristalline delta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2985512B1 (fr) * | 2012-01-05 | 2014-06-20 | Servier Lab | Procede de preparation du sel de l-arginine du perindopril |
CN103172696B (zh) * | 2012-12-19 | 2014-12-17 | 宁波美诺华药业股份有限公司 | 一种γ晶型的培哚普利精氨酸盐的制备方法 |
WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
EP3842035A1 (en) | 2019-12-23 | 2021-06-30 | KRKA, d.d., Novo mesto | Composition for the preparation of perindopril arginine granules, a method for their preparation and pharmaceutical composition comprising the granules |
SI26268A (sl) | 2021-11-18 | 2023-05-31 | Zupet Rok | Postopek za pripravo hidratirane oblike perindopril l-arginina |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2811319B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811320B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811318B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2838648B1 (fr) * | 2002-04-18 | 2004-05-21 | Servier Lab | Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent |
FR2841140B1 (fr) * | 2002-06-24 | 2004-10-01 | Servier Lab | Microcapsules pour la liberation retardee et controlee du perindopril |
-
2006
- 2006-02-28 FR FR0601747A patent/FR2897865B1/fr not_active Expired - Fee Related
-
2007
- 2007-02-26 DE DE602007006176T patent/DE602007006176D1/de active Active
- 2007-02-26 KR KR1020087023636A patent/KR20080106947A/ko active Search and Examination
- 2007-02-26 CA CA2643803A patent/CA2643803C/fr not_active Expired - Fee Related
- 2007-02-26 EP EP07731038A patent/EP2016051B1/fr active Active
- 2007-02-26 EA EA200801772A patent/EA014715B1/ru unknown
- 2007-02-26 DK DK07731038.1T patent/DK2016051T3/da active
- 2007-02-26 AU AU2007220434A patent/AU2007220434B2/en active Active
- 2007-02-26 PT PT07731038T patent/PT2016051E/pt unknown
- 2007-02-26 PL PL07731038T patent/PL2016051T3/pl unknown
- 2007-02-26 MX MX2008010747A patent/MX2008010747A/es active IP Right Grant
- 2007-02-26 WO PCT/FR2007/000334 patent/WO2007099216A2/fr active Application Filing
- 2007-02-26 UA UAA200811434A patent/UA89904C2/ru unknown
- 2007-02-26 BR BRPI0708291A patent/BRPI0708291B8/pt active IP Right Grant
- 2007-02-26 NZ NZ570366A patent/NZ570366A/en unknown
- 2007-02-26 CN CN2007800061997A patent/CN101389604B/zh active Active
- 2007-02-26 ME MEP-2010-330A patent/ME01805B/me unknown
- 2007-02-26 GE GEAP2007010917 patent/GEP20135839B/en unknown
- 2007-02-26 ES ES07731038T patent/ES2345291T3/es active Active
- 2007-02-26 RS RSP-2010/0330A patent/RS51431B/en unknown
- 2007-02-26 SI SI200730264T patent/SI2016051T1/sl unknown
- 2007-02-26 AT AT07731038T patent/ATE465992T1/de active
- 2007-02-26 JP JP2008556811A patent/JP5611524B2/ja active Active
- 2007-02-26 MY MYPI20082990A patent/MY143557A/en unknown
- 2007-02-26 US US12/224,415 patent/US7923569B2/en active Active
-
2008
- 2008-08-13 NO NO20083506A patent/NO341238B1/no unknown
- 2008-08-14 ZA ZA200807025A patent/ZA200807025B/xx unknown
- 2008-09-11 MA MA31233A patent/MA30277B1/fr unknown
-
2009
- 2009-08-24 HK HK09107754.2A patent/HK1129668A1/xx unknown
-
2010
- 2010-06-14 CY CY20101100547T patent/CY1110082T1/el unknown
- 2010-06-28 HR HR20100357T patent/HRP20100357T1/hr unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/02/2021, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/02/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |