EA200801772A1 - β КРИСТАЛЛИЧЕСКАЯ ФОРМА АРГИНИНОВОЙ СОЛИ ПЕРИНДОПРИЛА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ЕЁ СОДЕРЖАТ - Google Patents

β КРИСТАЛЛИЧЕСКАЯ ФОРМА АРГИНИНОВОЙ СОЛИ ПЕРИНДОПРИЛА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ЕЁ СОДЕРЖАТ

Info

Publication number
EA200801772A1
EA200801772A1 EA200801772A EA200801772A EA200801772A1 EA 200801772 A1 EA200801772 A1 EA 200801772A1 EA 200801772 A EA200801772 A EA 200801772A EA 200801772 A EA200801772 A EA 200801772A EA 200801772 A1 EA200801772 A1 EA 200801772A1
Authority
EA
Eurasian Patent Office
Prior art keywords
arginine salt
preparation
intensity
given
pharmaceutical compositions
Prior art date
Application number
EA200801772A
Other languages
English (en)
Other versions
EA014715B1 (ru
Inventor
Жерар Кокерель
Луа Лефебвре
Жан-Клод Сувье
Паскаль Отуар
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA200801772A1 publication Critical patent/EA200801772A1/ru
Publication of EA014715B1 publication Critical patent/EA014715B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

α кристаллическая форма соединения формулы (I), которая характеризуется ее рентгеновской дифракционной порошкограммой. Лекарственные средства.
EA200801772A 2006-02-28 2007-02-26 β-КРИСТАЛЛИЧЕСКАЯ ФОРМА АРГИНИНОВОЙ СОЛИ ПЕРИНДОПРИЛА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ЕЁ СОДЕРЖАТ EA014715B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0601747A FR2897865B1 (fr) 2006-02-28 2006-02-28 Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
PCT/FR2007/000334 WO2007099216A2 (fr) 2006-02-28 2007-02-26 FORME CRISTALLINE β DU SEL D'ARGININE DU PERINDOPRIL, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT

Publications (2)

Publication Number Publication Date
EA200801772A1 true EA200801772A1 (ru) 2009-02-27
EA014715B1 EA014715B1 (ru) 2011-02-28

Family

ID=37198804

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801772A EA014715B1 (ru) 2006-02-28 2007-02-26 β-КРИСТАЛЛИЧЕСКАЯ ФОРМА АРГИНИНОВОЙ СОЛИ ПЕРИНДОПРИЛА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ЕЁ СОДЕРЖАТ

Country Status (31)

Country Link
US (1) US7923569B2 (ru)
EP (1) EP2016051B1 (ru)
JP (1) JP5611524B2 (ru)
KR (1) KR20080106947A (ru)
CN (1) CN101389604B (ru)
AT (1) ATE465992T1 (ru)
AU (1) AU2007220434B2 (ru)
BR (1) BRPI0708291B8 (ru)
CA (1) CA2643803C (ru)
CY (1) CY1110082T1 (ru)
DE (1) DE602007006176D1 (ru)
DK (1) DK2016051T3 (ru)
EA (1) EA014715B1 (ru)
ES (1) ES2345291T3 (ru)
FR (1) FR2897865B1 (ru)
GE (1) GEP20135839B (ru)
HK (1) HK1129668A1 (ru)
HR (1) HRP20100357T1 (ru)
MA (1) MA30277B1 (ru)
ME (1) ME01805B (ru)
MX (1) MX2008010747A (ru)
MY (1) MY143557A (ru)
NO (1) NO341238B1 (ru)
NZ (1) NZ570366A (ru)
PL (1) PL2016051T3 (ru)
PT (1) PT2016051E (ru)
RS (1) RS51431B (ru)
SI (1) SI2016051T1 (ru)
UA (1) UA89904C2 (ru)
WO (1) WO2007099216A2 (ru)
ZA (1) ZA200807025B (ru)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA022573B1 (ru) * 2012-01-05 2016-01-29 Ле Лаборатуар Сервье Способ получения l-аргининовой соли периндоприла
EA022574B1 (ru) * 2012-01-05 2016-01-29 Ле Лаборатуар Сервье Дельта кристаллическая форма аргининовой соли периндоприла, способ ее получения и содержащие ее фармацевтические композиции

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2897866B1 (fr) 2006-02-28 2008-04-18 Servier Lab Forme cristalline alpha du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
AU2013245523C1 (en) * 2008-06-24 2017-09-07 Mylan Laboratories Ltd Novel polymorphic forms of Perindopril (L)-Arginine and process for the preparation thereof
PL2318365T3 (pl) * 2008-06-24 2016-02-29 Mylan Laboratories Ltd Nowe odmiany polimorficzne (L) argininianu peryndoprylu i sposoby ich wytwarzania
AU2009212902A1 (en) 2008-09-03 2010-03-18 Apotex Pharmachem Inc. Amorphous form of an L-arginine salt of perindopril and processes of preparation thereof
CN103172696B (zh) * 2012-12-19 2014-12-17 宁波美诺华药业股份有限公司 一种γ晶型的培哚普利精氨酸盐的制备方法
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity
FR3050380B1 (fr) 2016-04-20 2020-07-10 Les Laboratoires Servier Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains.
EP3842035A1 (en) 2019-12-23 2021-06-30 KRKA, d.d., Novo mesto Composition for the preparation of perindopril arginine granules, a method for their preparation and pharmaceutical composition comprising the granules
SI26268A (sl) 2021-11-18 2023-05-31 Zupet Rok Postopek za pripravo hidratirane oblike perindopril l-arginina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2811320B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811318B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811319B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2838648B1 (fr) * 2002-04-18 2004-05-21 Servier Lab Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent
FR2841140B1 (fr) * 2002-06-24 2004-10-01 Servier Lab Microcapsules pour la liberation retardee et controlee du perindopril

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA022573B1 (ru) * 2012-01-05 2016-01-29 Ле Лаборатуар Сервье Способ получения l-аргининовой соли периндоприла
EA022574B1 (ru) * 2012-01-05 2016-01-29 Ле Лаборатуар Сервье Дельта кристаллическая форма аргининовой соли периндоприла, способ ее получения и содержащие ее фармацевтические композиции

Also Published As

Publication number Publication date
WO2007099216A3 (fr) 2007-10-25
GEP20135839B (en) 2013-06-10
NZ570366A (en) 2011-05-27
RS51431B (en) 2011-04-30
PL2016051T3 (pl) 2010-08-31
DK2016051T3 (da) 2010-08-09
CN101389604B (zh) 2013-08-21
CA2643803C (fr) 2017-08-08
UA89904C2 (ru) 2010-03-10
AU2007220434A1 (en) 2007-09-07
HRP20100357T1 (hr) 2010-07-31
ME01805B (me) 2011-04-30
BRPI0708291A2 (pt) 2011-05-24
US7923569B2 (en) 2011-04-12
US20090186934A1 (en) 2009-07-23
CY1110082T1 (el) 2015-01-14
CA2643803A1 (fr) 2007-09-07
EA014715B1 (ru) 2011-02-28
WO2007099216A2 (fr) 2007-09-07
ZA200807025B (en) 2009-11-25
BRPI0708291B8 (pt) 2021-05-25
EP2016051B1 (fr) 2010-04-28
JP5611524B2 (ja) 2014-10-22
MX2008010747A (es) 2008-09-01
PT2016051E (pt) 2010-05-13
ATE465992T1 (de) 2010-05-15
DE602007006176D1 (de) 2010-06-10
ES2345291T3 (es) 2010-09-20
JP2009529500A (ja) 2009-08-20
EP2016051A2 (fr) 2009-01-21
KR20080106947A (ko) 2008-12-09
SI2016051T1 (sl) 2010-07-30
FR2897865A1 (fr) 2007-08-31
BRPI0708291B1 (pt) 2021-02-02
MY143557A (en) 2011-05-31
FR2897865B1 (fr) 2008-04-18
NO20083506L (no) 2008-08-13
MA30277B1 (fr) 2009-03-02
CN101389604A (zh) 2009-03-18
AU2007220434B2 (en) 2010-10-14
HK1129668A1 (ru) 2009-12-04
NO341238B1 (no) 2017-09-25

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