DE602007006176D1 - Beta-kristalline form von perindopril-arginin-salz, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen - Google Patents
Beta-kristalline form von perindopril-arginin-salz, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungenInfo
- Publication number
- DE602007006176D1 DE602007006176D1 DE602007006176T DE602007006176T DE602007006176D1 DE 602007006176 D1 DE602007006176 D1 DE 602007006176D1 DE 602007006176 T DE602007006176 T DE 602007006176T DE 602007006176 T DE602007006176 T DE 602007006176T DE 602007006176 D1 DE602007006176 D1 DE 602007006176D1
- Authority
- DE
- Germany
- Prior art keywords
- crystalline form
- arginine salt
- preparation
- perindopril
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0601747A FR2897865B1 (fr) | 2006-02-28 | 2006-02-28 | Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
PCT/FR2007/000334 WO2007099216A2 (fr) | 2006-02-28 | 2007-02-26 | FORME CRISTALLINE β DU SEL D'ARGININE DU PERINDOPRIL, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007006176D1 true DE602007006176D1 (de) | 2010-06-10 |
Family
ID=37198804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007006176T Active DE602007006176D1 (de) | 2006-02-28 | 2007-02-26 | Beta-kristalline form von perindopril-arginin-salz, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen |
Country Status (31)
Country | Link |
---|---|
US (1) | US7923569B2 (de) |
EP (1) | EP2016051B1 (de) |
JP (1) | JP5611524B2 (de) |
KR (1) | KR20080106947A (de) |
CN (1) | CN101389604B (de) |
AT (1) | ATE465992T1 (de) |
AU (1) | AU2007220434B2 (de) |
BR (1) | BRPI0708291B8 (de) |
CA (1) | CA2643803C (de) |
CY (1) | CY1110082T1 (de) |
DE (1) | DE602007006176D1 (de) |
DK (1) | DK2016051T3 (de) |
EA (1) | EA014715B1 (de) |
ES (1) | ES2345291T3 (de) |
FR (1) | FR2897865B1 (de) |
GE (1) | GEP20135839B (de) |
HK (1) | HK1129668A1 (de) |
HR (1) | HRP20100357T1 (de) |
MA (1) | MA30277B1 (de) |
ME (1) | ME01805B (de) |
MX (1) | MX2008010747A (de) |
MY (1) | MY143557A (de) |
NO (1) | NO341238B1 (de) |
NZ (1) | NZ570366A (de) |
PL (1) | PL2016051T3 (de) |
PT (1) | PT2016051E (de) |
RS (1) | RS51431B (de) |
SI (1) | SI2016051T1 (de) |
UA (1) | UA89904C2 (de) |
WO (1) | WO2007099216A2 (de) |
ZA (1) | ZA200807025B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2897866B1 (fr) | 2006-02-28 | 2008-04-18 | Servier Lab | Forme cristalline alpha du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
CA2919564A1 (en) * | 2008-06-24 | 2009-12-30 | Mylan Laboratories Limited | Polymorphic form gamma of perindopril (l)-arginine and processes for the preparation thereof |
AU2013245523C1 (en) * | 2008-06-24 | 2017-09-07 | Mylan Laboratories Ltd | Novel polymorphic forms of Perindopril (L)-Arginine and process for the preparation thereof |
AU2009212902A1 (en) | 2008-09-03 | 2010-03-18 | Apotex Pharmachem Inc. | Amorphous form of an L-arginine salt of perindopril and processes of preparation thereof |
FR2985512B1 (fr) * | 2012-01-05 | 2014-06-20 | Servier Lab | Procede de preparation du sel de l-arginine du perindopril |
FR2985511B1 (fr) * | 2012-01-05 | 2014-01-03 | Servier Lab | Forme cristalline delta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
CN103172696B (zh) * | 2012-12-19 | 2014-12-17 | 宁波美诺华药业股份有限公司 | 一种γ晶型的培哚普利精氨酸盐的制备方法 |
WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
EP3842035A1 (de) | 2019-12-23 | 2021-06-30 | KRKA, d.d., Novo mesto | Zusammensetzung zur herstellung von perindopril-arginin-granulaten, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung damit |
SI26268A (sl) | 2021-11-18 | 2023-05-31 | Zupet Rok | Postopek za pripravo hidratirane oblike perindopril l-arginina |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2811318B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811319B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811320B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2838648B1 (fr) * | 2002-04-18 | 2004-05-21 | Servier Lab | Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent |
FR2841140B1 (fr) * | 2002-06-24 | 2004-10-01 | Servier Lab | Microcapsules pour la liberation retardee et controlee du perindopril |
-
2006
- 2006-02-28 FR FR0601747A patent/FR2897865B1/fr not_active Expired - Fee Related
-
2007
- 2007-02-26 AT AT07731038T patent/ATE465992T1/de active
- 2007-02-26 GE GEAP2007010917 patent/GEP20135839B/en unknown
- 2007-02-26 EA EA200801772A patent/EA014715B1/ru unknown
- 2007-02-26 RS RSP-2010/0330A patent/RS51431B/en unknown
- 2007-02-26 BR BRPI0708291A patent/BRPI0708291B8/pt active IP Right Grant
- 2007-02-26 PL PL07731038T patent/PL2016051T3/pl unknown
- 2007-02-26 CN CN2007800061997A patent/CN101389604B/zh active Active
- 2007-02-26 AU AU2007220434A patent/AU2007220434B2/en active Active
- 2007-02-26 MX MX2008010747A patent/MX2008010747A/es active IP Right Grant
- 2007-02-26 DE DE602007006176T patent/DE602007006176D1/de active Active
- 2007-02-26 SI SI200730264T patent/SI2016051T1/sl unknown
- 2007-02-26 KR KR1020087023636A patent/KR20080106947A/ko active Search and Examination
- 2007-02-26 UA UAA200811434A patent/UA89904C2/ru unknown
- 2007-02-26 MY MYPI20082990A patent/MY143557A/en unknown
- 2007-02-26 EP EP07731038A patent/EP2016051B1/de active Active
- 2007-02-26 ES ES07731038T patent/ES2345291T3/es active Active
- 2007-02-26 US US12/224,415 patent/US7923569B2/en active Active
- 2007-02-26 NZ NZ570366A patent/NZ570366A/en unknown
- 2007-02-26 PT PT07731038T patent/PT2016051E/pt unknown
- 2007-02-26 JP JP2008556811A patent/JP5611524B2/ja active Active
- 2007-02-26 ME MEP-2010-330A patent/ME01805B/me unknown
- 2007-02-26 DK DK07731038.1T patent/DK2016051T3/da active
- 2007-02-26 CA CA2643803A patent/CA2643803C/fr not_active Expired - Fee Related
- 2007-02-26 WO PCT/FR2007/000334 patent/WO2007099216A2/fr active Application Filing
-
2008
- 2008-08-13 NO NO20083506A patent/NO341238B1/no unknown
- 2008-08-14 ZA ZA200807025A patent/ZA200807025B/xx unknown
- 2008-09-11 MA MA31233A patent/MA30277B1/fr unknown
-
2009
- 2009-08-24 HK HK09107754.2A patent/HK1129668A1/xx unknown
-
2010
- 2010-06-14 CY CY20101100547T patent/CY1110082T1/el unknown
- 2010-06-28 HR HR20100357T patent/HRP20100357T1/hr unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |