CY1117753T1 - Κρυσταλλικη μορφη του αλατος αργινινης της περινδοπριλης, μεθοδος παρασκευης της και φαρμακευτικες συνθεσεις οι οποιες την περιεχουν - Google Patents
Κρυσταλλικη μορφη του αλατος αργινινης της περινδοπριλης, μεθοδος παρασκευης της και φαρμακευτικες συνθεσεις οι οποιες την περιεχουνInfo
- Publication number
- CY1117753T1 CY1117753T1 CY20161100654T CY161100654T CY1117753T1 CY 1117753 T1 CY1117753 T1 CY 1117753T1 CY 20161100654 T CY20161100654 T CY 20161100654T CY 161100654 T CY161100654 T CY 161100654T CY 1117753 T1 CY1117753 T1 CY 1117753T1
- Authority
- CY
- Cyprus
- Prior art keywords
- crystalline form
- preparation
- pharmaceutical compositions
- compositions containing
- arginine salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Η κρυσταλλική μορφή α της ένωσης του τύπου (I) η οποία χαρακτηρίζεται από το διάγραμμα της περίθλασης Χ σε σκόνη. Φάρμακα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0601748A FR2897866B1 (fr) | 2006-02-28 | 2006-02-28 | Forme cristalline alpha du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
PCT/FR2007/000335 WO2007099217A1 (fr) | 2006-02-28 | 2007-02-26 | FORME CRISTALLINE α DU SEL D'ARGININE DU PERINDOPRIL, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1117753T1 true CY1117753T1 (el) | 2017-05-17 |
Family
ID=37022969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161100654T CY1117753T1 (el) | 2006-02-28 | 2016-07-11 | Κρυσταλλικη μορφη του αλατος αργινινης της περινδοπριλης, μεθοδος παρασκευης της και φαρμακευτικες συνθεσεις οι οποιες την περιεχουν |
Country Status (28)
Country | Link |
---|---|
US (1) | US7846961B2 (el) |
EP (1) | EP1989182B1 (el) |
JP (1) | JP5255454B2 (el) |
KR (2) | KR20120001818A (el) |
CN (1) | CN101389603B (el) |
AU (1) | AU2007220435B2 (el) |
BR (1) | BRPI0708278B8 (el) |
CA (1) | CA2644467C (el) |
CY (1) | CY1117753T1 (el) |
DK (1) | DK1989182T3 (el) |
EA (1) | EA014716B1 (el) |
ES (1) | ES2581982T3 (el) |
FR (1) | FR2897866B1 (el) |
GE (1) | GEP20125433B (el) |
HK (1) | HK1129669A1 (el) |
HR (1) | HRP20160644T1 (el) |
HU (1) | HUE027898T2 (el) |
MA (1) | MA30276B1 (el) |
ME (1) | ME02456B (el) |
MY (1) | MY151035A (el) |
NO (1) | NO20083535L (el) |
NZ (1) | NZ570367A (el) |
PL (1) | PL1989182T3 (el) |
RS (1) | RS54754B1 (el) |
SI (1) | SI1989182T1 (el) |
UA (1) | UA89905C2 (el) |
WO (1) | WO2007099217A1 (el) |
ZA (1) | ZA200807024B (el) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2318365T3 (en) * | 2008-06-24 | 2015-11-23 | Mylan Lab Ltd | NOVEL polymorphic forms of perindopril (L) -arginine AND PROCESS FOR PREPARATION THEREOF |
AU2009212902A1 (en) | 2008-09-03 | 2010-03-18 | Apotex Pharmachem Inc. | Amorphous form of an L-arginine salt of perindopril and processes of preparation thereof |
SI23149A (sl) | 2009-09-21 | 2011-03-31 | Silverstone Pharma | Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni |
FR2985512B1 (fr) * | 2012-01-05 | 2014-06-20 | Servier Lab | Procede de preparation du sel de l-arginine du perindopril |
FR2985511B1 (fr) * | 2012-01-05 | 2014-01-03 | Servier Lab | Forme cristalline delta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
CN103172696B (zh) * | 2012-12-19 | 2014-12-17 | 宁波美诺华药业股份有限公司 | 一种γ晶型的培哚普利精氨酸盐的制备方法 |
FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
EP3842035A1 (en) | 2019-12-23 | 2021-06-30 | KRKA, d.d., Novo mesto | Composition for the preparation of perindopril arginine granules, a method for their preparation and pharmaceutical composition comprising the granules |
SI26268A (sl) | 2021-11-18 | 2023-05-31 | Zupet Rok | Postopek za pripravo hidratirane oblike perindopril l-arginina |
CN114149357B (zh) * | 2021-12-29 | 2024-06-25 | 江苏嘉逸医药有限公司 | 一种γ晶型培哚普利精氨酸盐的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
FR2811318B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811320B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811319B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2838648B1 (fr) * | 2002-04-18 | 2004-05-21 | Servier Lab | Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent |
FR2897865B1 (fr) | 2006-02-28 | 2008-04-18 | Servier Lab | Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
DK2318365T3 (en) | 2008-06-24 | 2015-11-23 | Mylan Lab Ltd | NOVEL polymorphic forms of perindopril (L) -arginine AND PROCESS FOR PREPARATION THEREOF |
-
2006
- 2006-02-28 FR FR0601748A patent/FR2897866B1/fr active Active
-
2007
- 2007-02-26 EP EP07731039.9A patent/EP1989182B1/fr not_active Revoked
- 2007-02-26 NZ NZ570367A patent/NZ570367A/en unknown
- 2007-02-26 DK DK07731039.9T patent/DK1989182T3/en active
- 2007-02-26 KR KR1020117028452A patent/KR20120001818A/ko active Search and Examination
- 2007-02-26 UA UAA200811436A patent/UA89905C2/ru unknown
- 2007-02-26 PL PL07731039.9T patent/PL1989182T3/pl unknown
- 2007-02-26 RS RS20160321A patent/RS54754B1/sr unknown
- 2007-02-26 BR BRPI0708278A patent/BRPI0708278B8/pt active IP Right Grant
- 2007-02-26 CN CN2007800061889A patent/CN101389603B/zh active Active
- 2007-02-26 ZA ZA200807024A patent/ZA200807024B/xx unknown
- 2007-02-26 ES ES07731039.9T patent/ES2581982T3/es active Active
- 2007-02-26 CA CA2644467A patent/CA2644467C/fr not_active Expired - Fee Related
- 2007-02-26 JP JP2008556812A patent/JP5255454B2/ja active Active
- 2007-02-26 KR KR1020087023638A patent/KR20080106948A/ko not_active Application Discontinuation
- 2007-02-26 MY MYPI20082991 patent/MY151035A/en unknown
- 2007-02-26 EA EA200801777A patent/EA014716B1/ru unknown
- 2007-02-26 HU HUE07731039A patent/HUE027898T2/en unknown
- 2007-02-26 AU AU2007220435A patent/AU2007220435B2/en active Active
- 2007-02-26 ME MEP-2016-140A patent/ME02456B/me unknown
- 2007-02-26 WO PCT/FR2007/000335 patent/WO2007099217A1/fr active Application Filing
- 2007-02-26 GE GEAP200710918A patent/GEP20125433B/en unknown
- 2007-02-26 US US12/224,369 patent/US7846961B2/en active Active
- 2007-02-26 SI SI200731781A patent/SI1989182T1/sl unknown
-
2008
- 2008-08-14 NO NO20083535A patent/NO20083535L/no not_active Application Discontinuation
- 2008-09-11 MA MA31232A patent/MA30276B1/fr unknown
-
2009
- 2009-08-24 HK HK09107755.1A patent/HK1129669A1/xx unknown
-
2016
- 2016-06-09 HR HRP20160644TT patent/HRP20160644T1/hr unknown
- 2016-07-11 CY CY20161100654T patent/CY1117753T1/el unknown
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