BRPI0619255A8 - Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer - Google Patents
Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncerInfo
- Publication number
- BRPI0619255A8 BRPI0619255A8 BRPI0619255A BRPI0619255A BRPI0619255A8 BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8 BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- cancer immunotherapy
- pharmaceutical composition
- hydrogen atom
- drug
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 238000002619 cancer immunotherapy Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 ANTIBODY Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005346577 | 2005-11-30 | ||
JP2005-346577 | 2005-11-30 | ||
PCT/JP2006/323827 WO2007063903A1 (ja) | 2005-11-30 | 2006-11-29 | 新規ペプチド化合物 |
Publications (4)
Publication Number | Publication Date |
---|---|
BRPI0619255A2 BRPI0619255A2 (pt) | 2011-09-27 |
BRPI0619255A8 true BRPI0619255A8 (pt) | 2015-12-15 |
BRPI0619255B1 BRPI0619255B1 (pt) | 2021-05-11 |
BRPI0619255B8 BRPI0619255B8 (pt) | 2021-05-25 |
Family
ID=38092236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0619255A BRPI0619255B8 (pt) | 2005-11-30 | 2006-11-29 | composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer |
Country Status (18)
Country | Link |
---|---|
US (4) | US7939627B2 (pt) |
EP (1) | EP1961761B1 (pt) |
JP (4) | JP4394724B2 (pt) |
KR (1) | KR101385805B1 (pt) |
CN (2) | CN101336249A (pt) |
AU (1) | AU2006319892B2 (pt) |
BR (1) | BRPI0619255B8 (pt) |
CA (1) | CA2631292C (pt) |
DE (1) | DE602006017880D1 (pt) |
DK (1) | DK1961761T3 (pt) |
ES (1) | ES2352855T3 (pt) |
HK (2) | HK1122819A1 (pt) |
PL (1) | PL1961761T3 (pt) |
PT (1) | PT1961761E (pt) |
RU (1) | RU2424247C2 (pt) |
SI (1) | SI1961761T1 (pt) |
TW (1) | TWI372152B (pt) |
WO (1) | WO2007063903A1 (pt) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080070835A1 (en) | 2003-11-05 | 2008-03-20 | International Institute Of Cancer Immunology, Inc | Hla-Dr-Binding Antigen Peptide Derived From Wt1 |
US8765687B2 (en) | 2005-10-17 | 2014-07-01 | Sloan Kettering Institute For Cancer Research | WT1 HLA class II-binding peptides and compositions and methods comprising same |
JP4394724B2 (ja) * | 2005-11-30 | 2010-01-06 | 株式会社癌免疫研究所 | 新規ペプチド化合物 |
CA2645766A1 (en) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and methods of use thereof |
PT2119778E (pt) | 2007-02-27 | 2016-02-15 | Int Inst Cancer Immunology Inc | Método para ativação de célula t auxiliar e composição para utilização no método |
JP2011016751A (ja) * | 2009-07-08 | 2011-01-27 | Sumitomo Chemical Co Ltd | 光学活性3−アミノピペリジン−1−カルボキシレート化合物の製造方法およびその製造方法に用いられる中間体 |
BR112012025044A2 (pt) | 2010-03-31 | 2016-06-21 | Stabilitech Ltd | método para conservar adjuvantes de alum e vacinas com adjuvantes de alum |
US20130164296A1 (en) | 2010-03-31 | 2013-06-27 | Jeffrey Drew | Excipients for Stabilising Viral Particles, Polypeptides or Biological Material |
CA2795013C (en) | 2010-03-31 | 2018-10-16 | Stabilitech Ltd. | Stabilisation of viral particles |
AR083295A1 (es) | 2010-10-05 | 2013-02-13 | Univ Osaka | Metodo para activar celulas t auxiliares |
GB201117233D0 (en) | 2011-10-05 | 2011-11-16 | Stabilitech Ltd | Stabilisation of polypeptides |
US9539299B2 (en) * | 2011-10-27 | 2017-01-10 | International Institute Of Cancer Immunology, Inc. | Combination therapy with WT1 peptide vaccine and temozolomide |
EP3520810A3 (en) | 2012-01-13 | 2019-11-06 | Memorial Sloan-Kettering Cancer Center | Immunogenic wt1 peptides and use thereof |
WO2014007266A1 (ja) | 2012-07-02 | 2014-01-09 | 大日本住友製薬株式会社 | 癌抗原ペプチド経皮剤 |
CN104853764B (zh) * | 2012-12-13 | 2018-06-22 | 海德堡吕布莱希特-卡尔斯大学 | 用于预防和治疗癌症的msi-特异性移码肽(fsp) |
WO2014098012A1 (ja) | 2012-12-17 | 2014-06-26 | 大塚製薬株式会社 | ヘルパーt細胞の活性化方法 |
US9919037B2 (en) * | 2013-01-15 | 2018-03-20 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
RU2687144C2 (ru) | 2013-02-05 | 2019-05-07 | Нитто Денко Корпорейшн | Композиция противораковой вакцины, содержащей пептид wt1, для трансдермального введения |
US10195258B2 (en) | 2013-02-05 | 2019-02-05 | Nitto Denko Corporation | Tape preparation of WT1 peptide cancer vaccine for transdermal administration |
EP2762152A1 (en) | 2013-02-05 | 2014-08-06 | Nitto Denko Corporation | WT1 peptide cancer vaccine composition for transdermal administration |
CN103961702B (zh) | 2013-02-05 | 2019-04-09 | 日东电工株式会社 | 粘膜给予用wt1肽癌症疫苗组合物 |
WO2014136814A1 (ja) * | 2013-03-08 | 2014-09-12 | 大鵬薬品工業株式会社 | 新規ctlエピトープ5連結ペプチド |
ES2694328T3 (es) | 2013-03-12 | 2018-12-19 | Sumitomo Dainippon Pharma Co., Ltd. | Composición acuosa líquida |
WO2014157704A1 (ja) * | 2013-03-29 | 2014-10-02 | 大日本住友製薬株式会社 | Erap1によるトリミング機能をきっかけとしたコンジュゲートワクチン |
MY171854A (en) | 2013-03-29 | 2019-11-05 | Sumitomo Dainippon Pharma Co Ltd | Wt1 antigen peptide conjugate vaccine |
WO2015060235A1 (ja) | 2013-10-21 | 2015-04-30 | 大鵬薬品工業株式会社 | 新規ctlエピトープ4連結ペプチド |
GB201406569D0 (en) | 2014-04-11 | 2014-05-28 | Stabilitech Ltd | Vaccine compositions |
US10471136B2 (en) | 2014-09-27 | 2019-11-12 | Sumitomo Dainippon Pharma Co., Ltd. | Pharmaceutical composition for injection |
JP6671141B2 (ja) * | 2014-10-21 | 2020-03-25 | 大日本住友製薬株式会社 | 懸濁液剤 |
JP6699013B2 (ja) * | 2014-12-25 | 2020-05-27 | 国立大学法人三重大学 | Wt1由来ペプチド認識抗体 |
JP7209963B2 (ja) * | 2016-11-30 | 2023-01-23 | 住友ファーマ株式会社 | Wt1ヘルパーペプチド及びこれと癌抗原ペプチドコンジュゲート体との組合せ |
EP3604325A4 (en) | 2017-03-30 | 2021-01-13 | Sumitomo Dainippon Pharma Co., Ltd. | WT1 CANCER ANTIGEN PEPTIDE AND PEPTIDE CONJUGATE BODY WITH IT |
GB2562241B (en) | 2017-05-08 | 2022-04-06 | Stabilitech Biopharma Ltd | Vaccine compositions |
US20210338587A1 (en) | 2018-09-28 | 2021-11-04 | Sumitomo Dainippon Pharma Co., Ltd. | Injectable composition |
KR20210073540A (ko) | 2018-10-05 | 2021-06-18 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 양성 종양의 예방 또는 치료약 |
CN113412271A (zh) * | 2019-02-13 | 2021-09-17 | 大日本住友制药株式会社 | 具有半胱氨酸残基的哈米特林衍生物 |
AU2020255935A1 (en) | 2019-04-05 | 2021-12-02 | Sumitomo Pharma Co., Ltd. | Water soluble adjuvant and composition containing same |
KR20220004637A (ko) | 2019-04-05 | 2022-01-11 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 수용성 보조제 |
KR20230009426A (ko) | 2020-05-12 | 2023-01-17 | 스미토모 파마 가부시키가이샤 | 암을 처치하기 위한 의약 조성물 |
AU2022327884A1 (en) | 2021-08-12 | 2024-02-22 | International Institute Of Cancer Immunology, Inc. | Pharmaceutical composition and method for treatment or prevention of cancer |
Family Cites Families (23)
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US5858358A (en) * | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
US6297041B1 (en) * | 1992-03-11 | 2001-10-02 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
US6309642B1 (en) * | 1997-04-28 | 2001-10-30 | The Research And Development Institute, Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
US5858682A (en) * | 1996-08-02 | 1999-01-12 | Pharmingen | E2A/pbx1 fusion protein specific monoclonal antibodies |
AU4932199A (en) * | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
MXPA01003344A (es) | 1998-09-30 | 2004-04-21 | Corixa Corp | Composiciones y metodos para inmunoterapia especifica de wt1. |
GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
US7534605B2 (en) * | 1999-06-08 | 2009-05-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases |
US20040097703A1 (en) | 2001-03-22 | 2004-05-20 | Haruo Sugiyama | Wt1 modified peptide |
DE60235155D1 (de) * | 2001-04-17 | 2010-03-11 | Childrens Hosp Oak Res Inst | Monoklonale antikörper gegen molekulare mimetika von meningokokken-b-epitopen |
US20050002951A1 (en) * | 2001-09-28 | 2005-01-06 | Haruo Sugiyama | Novel method of inducing antigen-specific t cells |
US8735357B2 (en) * | 2001-09-28 | 2014-05-27 | International Institute Of Cancer Immunology, Inc. | Method of inducing antigen-specific T cells |
WO2003106682A1 (ja) * | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Hla−a24拘束性癌抗原ペプチド |
US7342092B2 (en) * | 2002-09-12 | 2008-03-11 | International Institute Of Cancer Immunology, Inc. | Cancer antigen peptide formulations |
DE60329201D1 (de) * | 2002-09-20 | 2009-10-22 | Chugai Pharmaceutical Co Ltd | Substituierte wt1-peptide |
CN1735864A (zh) * | 2003-01-13 | 2006-02-15 | 施克莱无线公司 | 主机可扩展无线应用接口 |
KR20120054644A (ko) * | 2003-01-15 | 2012-05-30 | 추가이 세이야쿠 가부시키가이샤 | 이량체화 펩티드 |
EP2343083B1 (en) * | 2003-06-27 | 2014-01-15 | International Institute of Cancer Immunology, Inc. | Method of diagnosing cancer comprising the measurement of WT1-specific CTL precursor cells |
US20080070835A1 (en) * | 2003-11-05 | 2008-03-20 | International Institute Of Cancer Immunology, Inc | Hla-Dr-Binding Antigen Peptide Derived From Wt1 |
EP1703887A4 (en) * | 2003-12-31 | 2009-10-21 | Univ Rochester | IMMUNOGENIC POLYPEPTIDES AND CONJUGATES THAT CAN INDUCE ANTIBODIES AGAINST PATHOGENIC AGENTS AND USES THEREOF |
DK1731605T3 (da) | 2004-03-31 | 2010-05-25 | Int Inst Cancer Immunology Inc | Cancerantigenpeptider der er afledt af WT1 |
WO2005121178A2 (en) * | 2004-06-08 | 2005-12-22 | Wisconsin Alumni Research Foundation | Immunoaffinity chromatography polyol-responsive monoclonal antibodies |
JP4394724B2 (ja) * | 2005-11-30 | 2010-01-06 | 株式会社癌免疫研究所 | 新規ペプチド化合物 |
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2006
- 2006-11-29 JP JP2007547975A patent/JP4394724B2/ja active Active
- 2006-11-29 PT PT06833631T patent/PT1961761E/pt unknown
- 2006-11-29 DE DE602006017880T patent/DE602006017880D1/de active Active
- 2006-11-29 EP EP06833631A patent/EP1961761B1/en active Active
- 2006-11-29 AU AU2006319892A patent/AU2006319892B2/en active Active
- 2006-11-29 SI SI200630824T patent/SI1961761T1/sl unknown
- 2006-11-29 KR KR1020087015751A patent/KR101385805B1/ko active IP Right Grant
- 2006-11-29 CN CNA2006800519144A patent/CN101336249A/zh active Pending
- 2006-11-29 US US12/095,418 patent/US7939627B2/en active Active
- 2006-11-29 ES ES06833631T patent/ES2352855T3/es active Active
- 2006-11-29 RU RU2008126305/04A patent/RU2424247C2/ru active
- 2006-11-29 WO PCT/JP2006/323827 patent/WO2007063903A1/ja active Application Filing
- 2006-11-29 BR BRPI0619255A patent/BRPI0619255B8/pt active IP Right Grant
- 2006-11-29 CN CN201510909871.XA patent/CN105315347A/zh active Pending
- 2006-11-29 CA CA2631292A patent/CA2631292C/en active Active
- 2006-11-29 PL PL06833631T patent/PL1961761T3/pl unknown
- 2006-11-29 DK DK06833631.2T patent/DK1961761T3/da active
- 2006-11-30 TW TW095144507A patent/TWI372152B/zh active
-
2008
- 2008-12-19 HK HK08113820.1A patent/HK1122819A1/xx unknown
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2009
- 2009-08-31 JP JP2009200003A patent/JP5049323B2/ja active Active
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2011
- 2011-03-22 US US13/053,996 patent/US8575308B2/en active Active
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2012
- 2012-03-29 JP JP2012077513A patent/JP5597668B2/ja active Active
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2013
- 2013-09-10 US US14/022,413 patent/US9273148B2/en active Active
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2014
- 2014-01-31 JP JP2014017168A patent/JP5800928B2/ja active Active
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2016
- 2016-02-26 US US15/054,805 patent/US9765114B2/en active Active
- 2016-08-02 HK HK16109195.6A patent/HK1221230A1/zh unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. |
|
B25A | Requested transfer of rights approved |
Owner name: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) , SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) Owner name: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C07K 7/06 (2006.01), A61K 39/00 (2006.01), C07K 14 |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
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