BRPI0619255A8 - Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer - Google Patents

Composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer

Info

Publication number
BRPI0619255A8
BRPI0619255A8 BRPI0619255A BRPI0619255A BRPI0619255A8 BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8 BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A BRPI0619255 A BR PI0619255A BR PI0619255 A8 BRPI0619255 A8 BR PI0619255A8
Authority
BR
Brazil
Prior art keywords
compound
cancer immunotherapy
pharmaceutical composition
hydrogen atom
drug
Prior art date
Application number
BRPI0619255A
Other languages
English (en)
Inventor
Nishihara Toshio
Gotoh Masashi
Original Assignee
Int Inst Cancer Immunology Inc
Dainippon Sumitomo Pharma Co
Chugai Seiyaku Kabishiki Kaisha
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc, Dainippon Sumitomo Pharma Co, Chugai Seiyaku Kabishiki Kaisha, Sumitomo Dainippon Pharma Co Ltd filed Critical Int Inst Cancer Immunology Inc
Publication of BRPI0619255A2 publication Critical patent/BRPI0619255A2/pt
Publication of BRPI0619255A8 publication Critical patent/BRPI0619255A8/pt
Publication of BRPI0619255B1 publication Critical patent/BRPI0619255B1/pt
Publication of BRPI0619255B8 publication Critical patent/BRPI0619255B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153Wilms tumor 1 [WT1]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production

Abstract

COMPOSTO DE PEPTÍDEO, COMPOSIÇÃO FARMACÊUTICA, ANTICORPO, USO DO COMPOSTO E MEDICAMENTO PARA IMUNOTERAPIA DE CÂNCER. A presente invenção refere-se a um composto da fórmula (1) em que X é um resíduo de tirosina ou um resíduo de metionina; Y e Z são, cada, uma ligação simples ou similar; R1 é um átomo de hidrogênio ou similar; R2 é um grupo hidróxi ou similar; R3 é um átomo de hidrogênio, grupo alquila, grupo amino ou similar; R4 é um átomo de hidrogênio, grupo alquila, grupo carbóxi ou similar; m é 1 ou 2; e n é um número inteiro de 0 a 2, com a condição de que quando n é 0, R3 é um átomo de hidrogênio ou um grupo alquila, ou um sal farmaceuticamente aceitável do mesmo, e seu uso em imunoterapia de câncer.
BRPI0619255A 2005-11-30 2006-11-29 composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer BRPI0619255B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005346577 2005-11-30
JP2005-346577 2005-11-30
PCT/JP2006/323827 WO2007063903A1 (ja) 2005-11-30 2006-11-29 新規ペプチド化合物

Publications (4)

Publication Number Publication Date
BRPI0619255A2 BRPI0619255A2 (pt) 2011-09-27
BRPI0619255A8 true BRPI0619255A8 (pt) 2015-12-15
BRPI0619255B1 BRPI0619255B1 (pt) 2021-05-11
BRPI0619255B8 BRPI0619255B8 (pt) 2021-05-25

Family

ID=38092236

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0619255A BRPI0619255B8 (pt) 2005-11-30 2006-11-29 composto de peptídeo, composição farmacêutica, uso do composto e medicamento para imunoterapia de câncer

Country Status (18)

Country Link
US (4) US7939627B2 (pt)
EP (1) EP1961761B1 (pt)
JP (4) JP4394724B2 (pt)
KR (1) KR101385805B1 (pt)
CN (2) CN101336249A (pt)
AU (1) AU2006319892B2 (pt)
BR (1) BRPI0619255B8 (pt)
CA (1) CA2631292C (pt)
DE (1) DE602006017880D1 (pt)
DK (1) DK1961761T3 (pt)
ES (1) ES2352855T3 (pt)
HK (2) HK1122819A1 (pt)
PL (1) PL1961761T3 (pt)
PT (1) PT1961761E (pt)
RU (1) RU2424247C2 (pt)
SI (1) SI1961761T1 (pt)
TW (1) TWI372152B (pt)
WO (1) WO2007063903A1 (pt)

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Also Published As

Publication number Publication date
PL1961761T3 (pl) 2011-04-29
EP1961761A1 (en) 2008-08-27
ES2352855T3 (es) 2011-02-23
KR20080073356A (ko) 2008-08-08
US7939627B2 (en) 2011-05-10
US20140046036A1 (en) 2014-02-13
AU2006319892A1 (en) 2007-06-07
PT1961761E (pt) 2010-12-16
KR101385805B1 (ko) 2014-04-16
CA2631292C (en) 2014-05-06
US20100062010A1 (en) 2010-03-11
US9273148B2 (en) 2016-03-01
JP5800928B2 (ja) 2015-10-28
HK1221230A1 (zh) 2017-05-26
DK1961761T3 (da) 2010-11-29
HK1122819A1 (en) 2009-05-29
US9765114B2 (en) 2017-09-19
BRPI0619255B1 (pt) 2021-05-11
EP1961761A4 (en) 2009-01-21
US20160168197A1 (en) 2016-06-16
WO2007063903A1 (ja) 2007-06-07
JPWO2007063903A1 (ja) 2009-05-07
RU2008126305A (ru) 2010-01-10
EP1961761B1 (en) 2010-10-27
BRPI0619255A2 (pt) 2011-09-27
BRPI0619255B8 (pt) 2021-05-25
SI1961761T1 (sl) 2010-12-31
JP5049323B2 (ja) 2012-10-17
AU2006319892B2 (en) 2012-05-10
RU2424247C2 (ru) 2011-07-20
TW200730540A (en) 2007-08-16
JP2014080435A (ja) 2014-05-08
CN101336249A (zh) 2008-12-31
JP5597668B2 (ja) 2014-10-01
JP2009286792A (ja) 2009-12-10
DE602006017880D1 (pt) 2010-12-09
TWI372152B (en) 2012-09-11
CN105315347A (zh) 2016-02-10
US8575308B2 (en) 2013-11-05
CA2631292A1 (en) 2007-06-07
JP4394724B2 (ja) 2010-01-06
JP2012158597A (ja) 2012-08-23
US20110229506A1 (en) 2011-09-22

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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Ipc: C07K 7/06 (2006.01), A61K 39/00 (2006.01), C07K 14

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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Owner name: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) ; SUMITOMO PHARMA CO., LTD. (JP)

B25G Requested change of headquarter approved

Owner name: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) ; SUMITOMO PHARMA CO., LTD. (JP)