BRPI0618599A2 - uso de um ácido alfa-cetoglutárico ou de um sal farmaceuticamente aceitável de ácido alfa-cetoglutárico - Google Patents

uso de um ácido alfa-cetoglutárico ou de um sal farmaceuticamente aceitável de ácido alfa-cetoglutárico Download PDF

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Publication number
BRPI0618599A2
BRPI0618599A2 BRPI0618599-1A BRPI0618599A BRPI0618599A2 BR PI0618599 A2 BRPI0618599 A2 BR PI0618599A2 BR PI0618599 A BRPI0618599 A BR PI0618599A BR PI0618599 A2 BRPI0618599 A2 BR PI0618599A2
Authority
BR
Brazil
Prior art keywords
alpha
akg
acid
ketoglutaric acid
pharmaceutically acceptable
Prior art date
Application number
BRPI0618599-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Stefan G Pierzynowski
Original Assignee
Entress Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entress Ab filed Critical Entress Ab
Publication of BRPI0618599A2 publication Critical patent/BRPI0618599A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0618599-1A 2005-11-15 2006-11-15 uso de um ácido alfa-cetoglutárico ou de um sal farmaceuticamente aceitável de ácido alfa-cetoglutárico BRPI0618599A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59717205P 2005-11-15 2005-11-15
US60/597172 2005-11-15
PCT/SE2006/050479 WO2007058612A1 (en) 2005-11-15 2006-11-15 Medicament for use in connection with cartilage impairment

Publications (1)

Publication Number Publication Date
BRPI0618599A2 true BRPI0618599A2 (pt) 2011-09-06

Family

ID=38048916

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0618599-1A BRPI0618599A2 (pt) 2005-11-15 2006-11-15 uso de um ácido alfa-cetoglutárico ou de um sal farmaceuticamente aceitável de ácido alfa-cetoglutárico

Country Status (10)

Country Link
US (2) US20090312427A1 (enExample)
EP (1) EP1951218A4 (enExample)
JP (1) JP2009515953A (enExample)
KR (1) KR20080074182A (enExample)
CN (2) CN101843609A (enExample)
AU (1) AU2006316059A1 (enExample)
BR (1) BRPI0618599A2 (enExample)
CA (1) CA2629683A1 (enExample)
RU (1) RU2454999C2 (enExample)
WO (1) WO2007058612A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090312427A1 (en) * 2005-11-15 2009-12-17 Entress Ab Medicament for Use in Connection With Cartilage Impairment
PL226695B1 (pl) 2006-07-03 2017-08-31 Danuta Kruszewska Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori
EP2106791A1 (en) * 2008-03-31 2009-10-07 Biotempt B.V. Glutamine or glutamine-containing dipeptide in a specific dosage for the treatment of inflammation
KR101080271B1 (ko) * 2009-03-31 2011-11-08 주식회사 웰스킨 다이펩타이드를 유효성분으로 포함하는 자외선에 의한 홍반반응 억제용 화장품 조성물
WO2011126163A1 (ko) * 2010-04-08 2011-10-13 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물
CN113018288A (zh) * 2019-12-25 2021-06-25 同济大学 α-酮戊二酸在制备药物中的用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687782A (en) * 1984-12-10 1987-08-18 Nutri-Fuels Systems, Inc. Nutritional composition for enhancing skeletal muscle adaptation to exercise training
SE9303691D0 (sv) * 1993-11-09 1993-11-09 Gramineer Ab New beverage
WO1998059035A2 (en) * 1997-06-25 1998-12-30 The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health Serum-free cell growth medium
US6846501B2 (en) * 2000-04-12 2005-01-25 Mid-America Commercialization Corporation Traditional snacks having balanced nutritional profiles
DE10057290B4 (de) * 2000-11-17 2004-01-08 Fresenius Kabi Deutschland Gmbh Enteral zu verabreichendes Supplement zur parenteralen Ernährung oder partiellen enteralen/oralen Ernährung bei kritisch Kranken, chronisch Kranken und Mangelernährten
SE0201713D0 (sv) * 2001-11-23 2002-06-06 Gramineer Internat Ab New methods and use III
RU2211037C1 (ru) * 2001-12-29 2003-08-27 Институт органической и физической химии им. А.Е.Арбузова Казанского научного центра РАН Препарат селективного действия и способ лечения остеоартрозов
WO2004028448A2 (en) * 2002-09-13 2004-04-08 Miller Kenneth E Method of alleviating pain via inhibition of neurotransmitter synthesis
DE602004002832T2 (de) * 2003-05-07 2007-06-06 Osteologix A/S Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
US20050176807A1 (en) * 2004-02-09 2005-08-11 Friesen Kim G. Composition and method for use in cartilage affecting conditions
JP2005312402A (ja) * 2004-04-30 2005-11-10 Kanazawa Univ Tlo Inc グルタミン酸伝達系を利用した骨・軟骨疾患治療薬の評価方法
PL368573A1 (en) * 2004-06-17 2005-12-27 Sgp & Sons Ab Pharmaceutical compound influencing growth and mineralization processes in the axial and the appendicular skeleton as well as bone diseases of mature years among humans and animals as well as application of the pharmaceutical compound in the process of growth and mineralization of axial and appendicular skeleton and bone diseases of mature years among humans and animals
PL371081A1 (pl) * 2004-11-08 2006-05-15 Sgp & Sons Ab Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt
US20090312427A1 (en) * 2005-11-15 2009-12-17 Entress Ab Medicament for Use in Connection With Cartilage Impairment

Also Published As

Publication number Publication date
CN101309678A (zh) 2008-11-19
KR20080074182A (ko) 2008-08-12
CN101309678B (zh) 2011-04-20
WO2007058612A1 (en) 2007-05-24
CN101843609A (zh) 2010-09-29
US20090312427A1 (en) 2009-12-17
RU2008123806A (ru) 2009-12-27
HK1126128A1 (en) 2009-08-28
AU2006316059A1 (en) 2007-05-24
RU2454999C2 (ru) 2012-07-10
US20110082086A1 (en) 2011-04-07
CA2629683A1 (en) 2007-05-24
EP1951218A4 (en) 2010-11-10
EP1951218A1 (en) 2008-08-06
JP2009515953A (ja) 2009-04-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2280 DE 16/09/2014.