BRPI0618385A2 - uso de uma combinação de testosterona ou um análogo da mesma com tadalafil, kit de partes, e, uso de uma combinação de testosterona ou um análogo da mesma com um composto - Google Patents
uso de uma combinação de testosterona ou um análogo da mesma com tadalafil, kit de partes, e, uso de uma combinação de testosterona ou um análogo da mesma com um composto Download PDFInfo
- Publication number
- BRPI0618385A2 BRPI0618385A2 BRPI0618385-9A BRPI0618385A BRPI0618385A2 BR PI0618385 A2 BRPI0618385 A2 BR PI0618385A2 BR PI0618385 A BRPI0618385 A BR PI0618385A BR PI0618385 A2 BRPI0618385 A2 BR PI0618385A2
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- Prior art keywords
- analog
- testosterone
- combination
- tadalafil
- female sexual
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
USO DE UMA COMBINAçãO DE TESTOSTERONA OU UM ANáLOGO DA MESMA COM TADALAFIL, KIT DE PARTES, E, USO DE UMA COMBINAçãO DE TESTOSTERONA OU UM ANALOGO DA MESMA COM UM COMPOSTO. A invenção diz respeito ao campo da disfunção sexual feminina. Especificamente diz respeito à influência da combinação da testosterona ou um análogo da mesma, com o tadalafil, sobre a saúde sexual em indivíduos femininos com Disfunção Sexual Feminina (tal como o Distúrbio de Excitação Sexual Feminina (FSAD) ou Distúrbio do Desejo Sexual Feminino (FSDD). Diz respeito ainda à influência da combinação da testosterona, ou de um análogo do mesmo, com um composto capaz de, pelo menos em parte, inibir a contração dos músculos lisos, por exemplo um composto capaz de, pelo menos em parte, inibir a tonalidade adrenérgica. A invenção ainda descreve outras terapias combinatórias no tratamento da Disfunção Sexual Feminina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05077577A EP1790343A1 (en) | 2005-11-11 | 2005-11-11 | Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction |
PCT/NL2006/000542 WO2007055563A2 (en) | 2005-11-11 | 2006-11-10 | Pharmaceutical combinations comprising testosterone in the treatment of female sexual dysfunction |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0618385A2 true BRPI0618385A2 (pt) | 2011-08-30 |
Family
ID=36118697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0618385-9A BRPI0618385A2 (pt) | 2005-11-11 | 2006-11-10 | uso de uma combinação de testosterona ou um análogo da mesma com tadalafil, kit de partes, e, uso de uma combinação de testosterona ou um análogo da mesma com um composto |
Country Status (27)
Country | Link |
---|---|
US (3) | US9333203B2 (pt) |
EP (2) | EP1790343A1 (pt) |
JP (2) | JP2009515875A (pt) |
KR (5) | KR20170029011A (pt) |
CN (2) | CN103083325B (pt) |
AU (1) | AU2006312373B2 (pt) |
BR (1) | BRPI0618385A2 (pt) |
CA (1) | CA2629364C (pt) |
CY (1) | CY1122051T1 (pt) |
DK (1) | DK1965802T3 (pt) |
EA (2) | EA034539B1 (pt) |
ES (1) | ES2744206T3 (pt) |
HK (1) | HK1128226A1 (pt) |
HR (1) | HRP20191544T1 (pt) |
HU (1) | HUE045846T2 (pt) |
IL (1) | IL191280A (pt) |
LT (1) | LT1965802T (pt) |
ME (1) | ME03499B (pt) |
NO (3) | NO342986B1 (pt) |
NZ (1) | NZ567963A (pt) |
PL (1) | PL1965802T3 (pt) |
PT (1) | PT1965802T (pt) |
RS (1) | RS59268B1 (pt) |
SI (1) | SI1965802T1 (pt) |
UA (2) | UA97101C2 (pt) |
WO (1) | WO2007055563A2 (pt) |
ZA (2) | ZA200804443B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2005239962B2 (en) | 2004-05-11 | 2011-07-07 | Eb Ip Lybrido B.V. | Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction |
EP1790343A1 (en) | 2005-11-11 | 2007-05-30 | Emotional Brain B.V. | Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction |
EP1925307A1 (en) | 2006-11-03 | 2008-05-28 | Emotional Brain B.V. | Use of 3-alpha-androstanediol in the treatment of sexual dysfunction |
US20120010216A1 (en) * | 2010-07-06 | 2012-01-12 | Brown Arthur M | Pharmaceutical compositions containing vanoxerine |
ES2825799T3 (es) * | 2011-05-13 | 2021-05-17 | Acerus Biopharma Inc | Formulaciones en gel de testosterona intranasal de concentración de dosis más baja y uso de las mismas para tratar anorgasmia o trastorno del deseo sexual hipoactivo |
MX2013013369A (es) * | 2011-05-15 | 2014-10-17 | Trimel Biopharma Srl | Formulaciones de gel bioadhesivo de testosterona intranasal y uso del mismo para tratar hipogonadismo masculino. |
FR2999086B1 (fr) * | 2012-12-10 | 2015-04-10 | Ethypharm Sa | Composition orale et/ou buccale sous forme de film fin d'un principe actif faiblement soluble, son procede de preparation et son utilisation |
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WO2016201286A1 (en) * | 2015-06-11 | 2016-12-15 | Applied Biology, Inc. | Treatment of sexual dysfunction |
US11717495B2 (en) * | 2020-03-16 | 2023-08-08 | Vella Bioscience, Inc. | Use of cannabinoids in treating anti-depressant-induced female sexual dysfunction |
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EP1925307A1 (en) * | 2006-11-03 | 2008-05-28 | Emotional Brain B.V. | Use of 3-alpha-androstanediol in the treatment of sexual dysfunction |
HUE027647T2 (en) | 2007-11-28 | 2016-10-28 | Ucb Pharma Gmbh | Polymorphic form of Rotigotine |
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