BRPI0606834A2 - usos de óxido nìtrico (no), dispositivo não implantável configurado, processo para fabricação de dispositivo configurado, uso de polìmero eluente de óxido nìtrico (no) e método de tratamento - Google Patents
usos de óxido nìtrico (no), dispositivo não implantável configurado, processo para fabricação de dispositivo configurado, uso de polìmero eluente de óxido nìtrico (no) e método de tratamentoInfo
- Publication number
- BRPI0606834A2 BRPI0606834A2 BRPI0606834-0A BRPI0606834A BRPI0606834A2 BR PI0606834 A2 BRPI0606834 A2 BR PI0606834A2 BR PI0606834 A BRPI0606834 A BR PI0606834A BR PI0606834 A2 BRPI0606834 A2 BR PI0606834A2
- Authority
- BR
- Brazil
- Prior art keywords
- nitric oxide
- eluting polymer
- neuropathy
- treatment method
- manufacturing process
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/114—Nitric oxide, i.e. NO
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
- A61L2300/622—Microcapsules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
- A61L2300/624—Nanocapsules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
USOS DE óXIDO NìTRICO (NO), DISPOSITIVO NãO IMPLANTáVEL CONFIGURADO, PROCESSO PARA FABRICAçãO DE DISPOSITIVO CONFIGURADO, USO DE POLìMERO ELUENTE DE óXIDO NìTRICO (NO) E MéTODO DE TRATAMENTO. A presente invenção refere-se a um dispositivo que permite o tratamento alvo de neuropatia, tal como neuropatia periférica diabética, ou neuropatia e úlceras resultantes da mencionada neuropatia. O dispositivo compreende um polímero eluente de óxido nítrico (NO) disposto para ficar emcontato com a área de tratamento, de tal forma que uma dose terapêutica de óxido nítrico é eluída do mencionado polímero eluente de óxido nítrico para a mencionada área. O polímero eluente de óxido nítrico (NO) é integrado com umveículo, de tal forma que o veículo, durante o uso, regule e controle a eluição da dosagem terapêutica de óxido nítrico (NO). Além disso, é descrito um método de fabricação correspondente para o dispositivo.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05002935A EP1690558A1 (en) | 2005-02-11 | 2005-02-11 | Device for treatment of diabetic disorders |
US65276005P | 2005-02-14 | 2005-02-14 | |
EP05018269A EP1757278A1 (en) | 2005-08-23 | 2005-08-23 | Device, system, and method comprising microencapsulated liquid for release of nitric oxide from a polymer |
US71100605P | 2005-08-24 | 2005-08-24 | |
PCT/EP2006/050891 WO2006084912A1 (en) | 2005-02-11 | 2006-02-13 | Device method, and use for treatment of neuropathy involving nitric oxide |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0606834A2 true BRPI0606834A2 (pt) | 2009-07-21 |
Family
ID=39188888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0606834-0A BRPI0606834A2 (pt) | 2005-02-11 | 2006-02-13 | usos de óxido nìtrico (no), dispositivo não implantável configurado, processo para fabricação de dispositivo configurado, uso de polìmero eluente de óxido nìtrico (no) e método de tratamento |
Country Status (12)
Country | Link |
---|---|
US (1) | US8241650B2 (pt) |
EP (2) | EP1846058B1 (pt) |
JP (2) | JP5175107B2 (pt) |
KR (1) | KR20070105331A (pt) |
BR (1) | BRPI0606834A2 (pt) |
CA (1) | CA2594407C (pt) |
DE (1) | DE602006007808D1 (pt) |
DK (1) | DK1846058T3 (pt) |
ES (1) | ES2329930T3 (pt) |
MX (1) | MX2007009690A (pt) |
PL (1) | PL1846058T3 (pt) |
WO (1) | WO2006084912A1 (pt) |
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EP1718316A4 (en) | 2004-02-09 | 2009-05-13 | Amulet Pharmaceuticals Inc | STAIN OXIDE RELEASING POLYMERS |
DE602006007808D1 (de) * | 2005-02-11 | 2009-08-27 | Nolabs Ab | Vorrichtung, verfahren und verwendung zur behandlung von neuropathie mit stickoxid |
WO2006100154A1 (en) | 2005-03-24 | 2006-09-28 | Nolabs Ab | Cosmetic treatment with nitric oxide, device for performing said treatment and manufacturing method therefor |
ES2731298T3 (es) | 2005-05-27 | 2019-11-14 | Univ North Carolina Chapel Hill | Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas |
US8221690B2 (en) | 2007-10-30 | 2012-07-17 | The Invention Science Fund I, Llc | Systems and devices that utilize photolyzable nitric oxide donors |
US8642093B2 (en) | 2007-10-30 | 2014-02-04 | The Invention Science Fund I, Llc | Methods and systems for use of photolyzable nitric oxide donors |
US7846400B2 (en) | 2007-10-30 | 2010-12-07 | The Invention Science Fund I, Llc | Substrates for nitric oxide releasing devices |
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US8980332B2 (en) | 2007-10-30 | 2015-03-17 | The Invention Science Fund I, Llc | Methods and systems for use of photolyzable nitric oxide donors |
US8877508B2 (en) | 2007-10-30 | 2014-11-04 | The Invention Science Fund I, Llc | Devices and systems that deliver nitric oxide |
US20100069887A1 (en) * | 2008-09-16 | 2010-03-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Multiple chamber ex vivo adjustable-release final dosage form |
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US20100068283A1 (en) | 2008-09-16 | 2010-03-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Ex VIVO modifiable particle or polymeric material medicament carrier |
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CN102695528B (zh) | 2009-08-21 | 2016-07-13 | 诺万公司 | 创伤敷料、其使用方法及其形成方法 |
JP5758904B2 (ja) | 2009-10-14 | 2015-08-05 | セラバスク インコーポレーテッド | ニトライトの医薬製剤及びそれらの使用 |
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ES2804263T3 (es) | 2011-07-05 | 2021-02-05 | Novan Inc | Composiciones tópicas |
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US9636521B2 (en) | 2013-07-12 | 2017-05-02 | Jonathan Isserow | Heat and light treatment device using nanotechnology |
US10010445B2 (en) | 2013-01-23 | 2018-07-03 | Jonathan Isserow | Treatment device using nanotechnology |
US10583037B2 (en) | 2013-01-23 | 2020-03-10 | Transqtronics, Llc. | Heating device using exothermic chemical reaction |
US9675817B2 (en) | 2013-01-23 | 2017-06-13 | Jonathan Isserow | Heating device using exothermic chemical reaction |
US9855211B2 (en) | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
KR101743124B1 (ko) | 2013-03-07 | 2017-06-02 | 주식회사 아이센스 | 일산화질소를 저장, 전달 할 수 있는 나노섬유의 제조방법 및 이에 의하여 제조된 일산화질소를 저장, 전달 할 수 있는 나노섬유 |
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2006
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- 2006-02-13 DK DK06708229T patent/DK1846058T3/da active
- 2006-02-13 EP EP06708229A patent/EP1846058B1/en active Active
- 2006-02-13 BR BRPI0606834-0A patent/BRPI0606834A2/pt not_active IP Right Cessation
- 2006-02-13 KR KR1020077018436A patent/KR20070105331A/ko not_active Application Discontinuation
- 2006-02-13 EP EP09165415A patent/EP2119459A1/en not_active Ceased
- 2006-02-13 WO PCT/EP2006/050891 patent/WO2006084912A1/en active Application Filing
- 2006-02-13 MX MX2007009690A patent/MX2007009690A/es active IP Right Grant
- 2006-02-13 PL PL06708229T patent/PL1846058T3/pl unknown
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- 2006-02-13 CA CA2594407A patent/CA2594407C/en active Active
- 2006-02-13 JP JP2007554578A patent/JP5175107B2/ja active Active
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US8241650B2 (en) | 2012-08-14 |
DE602006007808D1 (de) | 2009-08-27 |
EP1846058B1 (en) | 2009-07-15 |
KR20070105331A (ko) | 2007-10-30 |
WO2006084912A8 (en) | 2007-09-07 |
WO2006084912A1 (en) | 2006-08-17 |
US20080069848A1 (en) | 2008-03-20 |
EP2119459A1 (en) | 2009-11-18 |
JP5175107B2 (ja) | 2013-04-03 |
CA2594407C (en) | 2014-06-10 |
ES2329930T3 (es) | 2009-12-02 |
JP2008530055A (ja) | 2008-08-07 |
CA2594407A1 (en) | 2006-08-17 |
MX2007009690A (es) | 2007-10-15 |
DK1846058T3 (da) | 2009-11-23 |
EP1846058A1 (en) | 2007-10-24 |
PL1846058T3 (pl) | 2009-12-31 |
JP2013047241A (ja) | 2013-03-07 |
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