BRPI0518328A2 - agente de contraste, composiÇço farmacÊutica, uso de um agente de contraste, mÉtodo para gerar imagens realÇadas de um corpo animal ou humano, e, kit para a preparaÇço de um composiÇço radiofarmacÊutica - Google Patents

agente de contraste, composiÇço farmacÊutica, uso de um agente de contraste, mÉtodo para gerar imagens realÇadas de um corpo animal ou humano, e, kit para a preparaÇço de um composiÇço radiofarmacÊutica

Info

Publication number
BRPI0518328A2
BRPI0518328A2 BRPI0518328-6A BRPI0518328A BRPI0518328A2 BR PI0518328 A2 BRPI0518328 A2 BR PI0518328A2 BR PI0518328 A BRPI0518328 A BR PI0518328A BR PI0518328 A2 BRPI0518328 A2 BR PI0518328A2
Authority
BR
Brazil
Prior art keywords
contrast agent
animal
kit
preparation
human body
Prior art date
Application number
BRPI0518328-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Dagfinn Lovhaug
Morten Eriksen
Hege B Fjerdingstad
Andrew Healey
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of BRPI0518328A2 publication Critical patent/BRPI0518328A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056Peptides, proteins, polyamino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
BRPI0518328-6A 2004-11-22 2005-11-21 agente de contraste, composiÇço farmacÊutica, uso de um agente de contraste, mÉtodo para gerar imagens realÇadas de um corpo animal ou humano, e, kit para a preparaÇço de um composiÇço radiofarmacÊutica BRPI0518328A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20045081 2004-11-22
PCT/NO2005/000435 WO2006054904A2 (en) 2004-11-22 2005-11-21 Contrast agents to target extracellular matrix

Publications (1)

Publication Number Publication Date
BRPI0518328A2 true BRPI0518328A2 (pt) 2008-11-11

Family

ID=36182407

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518328-6A BRPI0518328A2 (pt) 2004-11-22 2005-11-21 agente de contraste, composiÇço farmacÊutica, uso de um agente de contraste, mÉtodo para gerar imagens realÇadas de um corpo animal ou humano, e, kit para a preparaÇço de um composiÇço radiofarmacÊutica

Country Status (17)

Country Link
US (1) US8182790B2 (enExample)
EP (2) EP2243496A3 (enExample)
JP (2) JP5116480B2 (enExample)
KR (1) KR20070091609A (enExample)
CN (1) CN101107016B (enExample)
AT (1) ATE494913T1 (enExample)
AU (1) AU2005307195A1 (enExample)
BR (1) BRPI0518328A2 (enExample)
CA (1) CA2586621A1 (enExample)
DE (1) DE602005025911D1 (enExample)
ES (1) ES2358745T3 (enExample)
IL (1) IL182898A0 (enExample)
MX (1) MX2007006050A (enExample)
NO (1) NO20073039L (enExample)
RU (1) RU2007118385A (enExample)
WO (1) WO2006054904A2 (enExample)
ZA (1) ZA200705043B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
US20100233082A1 (en) * 2006-08-28 2010-09-16 Bengt Langstrom 68GA-Labeled Peptide-Based Radiopharmaceuticals
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
WO2009074628A1 (en) * 2007-12-13 2009-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis
AU2009205950C1 (en) 2008-01-18 2015-08-06 Visen Medical, Inc. Fluorescent imaging agents
WO2009140408A2 (en) 2008-05-13 2009-11-19 University Of Kansas Metal abstraction peptide (map) tag and associated methods
GB0814722D0 (en) * 2008-08-12 2008-09-17 Ge Healthcare Ltd Treatment monitoring
GB0910013D0 (en) * 2009-06-10 2009-07-22 Ge Healthcare Ltd PET imaging of fibogenesis
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
CN102504603B (zh) * 2011-10-20 2014-01-29 中国海洋大学 一种多聚物与生物染色剂的偶合物及其制备方法和用途
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CN105939732A (zh) * 2013-12-03 2016-09-14 通用医疗公司 分子成像探针
CN117623996B (zh) * 2022-08-10 2025-07-22 中国药科大学 一种二价keap1-nrf2抑制剂、制备方法及其医药用途

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6048982A (en) 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
JP3038339B2 (ja) 1988-05-02 2000-05-08 ザイナクシス・テクノロジーズ・インコーポレーテッド バイオ粒子の表面膜に対してバイオアフェクティング物質を結合する化合物
GB8903022D0 (en) 1989-02-10 1989-03-30 Celltech Ltd Chemical compounds
WO1993011120A1 (en) 1991-11-27 1993-06-10 Zynaxis Technologies, Incorporated Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles
KR20000052830A (ko) 1996-10-28 2000-08-25 조오지 디빈센조, 토브 아스 헬지, 에바 요한손 진단/치료제 또는 그와 관련된 개선
ES2257771T3 (es) 1996-10-28 2006-08-01 Amersham Health As Agentes de contraste.
CA2278200A1 (en) * 1997-01-29 1998-07-30 Nycomed Imaging As Polymers
JP4549528B2 (ja) 1997-07-28 2010-09-22 ジーイー・ヘルスケア・リミテッド シアニン色素
US5942637A (en) 1998-03-30 1999-08-24 North Dakota State University Research Foundation Compounds containing tetradecachlorocyclohexasilane dianion
US6852318B1 (en) 1998-05-08 2005-02-08 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
EP1075277B2 (en) * 1998-05-08 2012-10-31 The Regents of the University of California Methods for detecting and inhibiting angiogenesis
JP2000095758A (ja) 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US6230777B1 (en) 1999-02-04 2001-05-15 Midmac Systems, Inc. Filter forming and joining apparatus
AU2001250683B2 (en) * 2000-04-12 2006-06-29 Ge Healthcare As Peptide-based compounds
NO20004795D0 (no) 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
CA2429956A1 (en) * 2000-11-27 2002-07-18 Alan P. Carpenter, Jr. Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
IL159310A0 (en) * 2001-07-10 2004-06-01 Amersham Health As Peptide-based compounds
GB0116815D0 (en) * 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
ATE412420T1 (de) 2002-06-17 2008-11-15 Cartela R & D Ab Verfahren und verwendungszwecke der integrin alpha 10 kette zur diagnose und nachweis von atherosklerotischer plaquebildung in vitro
US7063158B2 (en) 2003-06-16 2006-06-20 Deepwater Technologies, Inc. Bottom tensioned offshore oil well production riser
NO20033115D0 (no) 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0317815D0 (en) * 2003-07-30 2003-09-03 Amersham Health As Imaging agents
WO2005019247A2 (en) 2003-08-15 2005-03-03 Board Of Regents, The University Of Texas System Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
JP2007512321A (ja) * 2003-11-24 2007-05-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US7763234B2 (en) * 2004-03-04 2010-07-27 Ge Healthcare As Pharmaceutical compounds
WO2005123768A1 (en) * 2004-06-16 2005-12-29 Ge Healthcare As Peptide-based compounds
US8361443B2 (en) * 2004-06-16 2013-01-29 Ge Healthcare As Peptide-based compounds

Also Published As

Publication number Publication date
JP2012207027A (ja) 2012-10-25
KR20070091609A (ko) 2007-09-11
US8182790B2 (en) 2012-05-22
AU2005307195A1 (en) 2006-05-26
IL182898A0 (en) 2007-08-19
WO2006054904A2 (en) 2006-05-26
JP5116480B2 (ja) 2013-01-09
WO2006054904A3 (en) 2007-04-05
JP2008520658A (ja) 2008-06-19
EP1814598A2 (en) 2007-08-08
EP2243496A3 (en) 2012-12-26
CN101107016B (zh) 2011-11-16
EP1814598B1 (en) 2011-01-12
NO20073039L (no) 2007-08-16
DE602005025911D1 (de) 2011-02-24
ZA200705043B (en) 2008-09-25
ES2358745T3 (es) 2011-05-13
EP2243496A2 (en) 2010-10-27
ATE494913T1 (de) 2011-01-15
US20090208412A1 (en) 2009-08-20
MX2007006050A (es) 2007-11-14
RU2007118385A (ru) 2008-12-27
CN101107016A (zh) 2008-01-16
CA2586621A1 (en) 2006-05-26

Similar Documents

Publication Publication Date Title
NO20073039L (no) Kontrastmidler
UA103758C2 (ru) Конъюгаты олигомеров инсулина, их композиции и применение
BRPI0515175A (pt) método para radiofluoração, composto, composição radiofarmacêutica, uso de um conjugado radiorrotulado ou um sal do mesmo, método para diagnose ou formação de imagem in vivo de uma doença ou condição associada com a angiogênese, e, método para monitorar o efeito do tratamento de um corpo humano ou animal com um medicamento para combater uma condição associada com cáncer
CY1114679T1 (el) Συνθεσεις για διαγνωση και θεραπεια ασθενειων που συνδυαζονται με παρεκκλινουσα εκφραση φουτρινων (r-σπονδινων)
DK0836380T3 (da) FGF9 som en specifik ligand for FGFR3
WO1998018497A3 (en) Contrast agents
DK1409544T3 (da) Humane DR4-antistoffer og anvendelser deraf
GB0421639D0 (en) Methods and compositions relating to alzheimer's disease
WO2001082975A3 (en) Membrane-permeant peptide complexes for medical imaging
AU6160201A (en) Human polypeptides causing or leading to the killing of cells including lymphoidtumor cells
BR0003987A (pt) Composição laxativa
GT200600001A (es) Uso de colorantes de cianina para el diagnostico de enfermedades proliferativas
WO2001092283A3 (en) Cobalamin compounds useful as cardiovascular agents and as imaging agents
BRPI0416528A (pt) agente de formação de imagem, composição farmacêutica, composição radiofarmacêutica, conjugado, kit para a preparação da composição radiofarmacêutica, e, uso do agente de formação de imagem
CY1109868T1 (el) Cd81 πρωτεϊνη υποδοχεας ηπατιτιδας c
BRPI0416938A (pt) agente de formação de imagem, composição, conjugado, kit para a preparação da composição radiofarmacêutica
BR0009472A (pt) Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas
DK1228770T3 (da) Törret kontrastmiddel
ATE425770T1 (de) Kontrastmittel
WO2004002984A3 (fr) Composes de maleimides marques, leur procede de preparation et leur utilisation pour le marquage de macromolecules
GR3020861T3 (en) Mri image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands
BRPI0515894A (pt) agente de formação de imagem, composições farmacêutica e radiofarmacêutica, conjugado de um inibidor de metaloproteinase matricial com um ligando, precursor para a preparação da composição radiofarmacêutica, kit para a preparação da composição radiofarmacêutica, e, uso do agente de formação de imagem
BRPI0412453A (pt) uso do ácido ascórbico ou um sal fisiologicamente aceitável do mesmo
BR0207327A (pt) Amino derivados de biotina e seus conjugados com agentes quelantes macrocìclicos
WO2005049095A3 (en) Contrast agent imaging angiotensin ii receptors

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]