ZA200705043B - Contrast agents to target extracellular matrix - Google Patents

Contrast agents to target extracellular matrix

Info

Publication number
ZA200705043B
ZA200705043B ZA200705043A ZA200705043A ZA200705043B ZA 200705043 B ZA200705043 B ZA 200705043B ZA 200705043 A ZA200705043 A ZA 200705043A ZA 200705043 A ZA200705043 A ZA 200705043A ZA 200705043 B ZA200705043 B ZA 200705043B
Authority
ZA
South Africa
Prior art keywords
extracellular matrix
contrast agents
target extracellular
target
biomodifier
Prior art date
Application number
ZA200705043A
Other languages
English (en)
Inventor
Loevhaug Dagfinn
Hege B Fjerdingstad
Eriksen Morten
Healey Andrew
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of ZA200705043B publication Critical patent/ZA200705043B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
ZA200705043A 2004-11-22 2007-06-07 Contrast agents to target extracellular matrix ZA200705043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO20045081 2004-11-22

Publications (1)

Publication Number Publication Date
ZA200705043B true ZA200705043B (en) 2008-09-25

Family

ID=36182407

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200705043A ZA200705043B (en) 2004-11-22 2007-06-07 Contrast agents to target extracellular matrix

Country Status (17)

Country Link
US (1) US8182790B2 (enExample)
EP (2) EP2243496A3 (enExample)
JP (2) JP5116480B2 (enExample)
KR (1) KR20070091609A (enExample)
CN (1) CN101107016B (enExample)
AT (1) ATE494913T1 (enExample)
AU (1) AU2005307195A1 (enExample)
BR (1) BRPI0518328A2 (enExample)
CA (1) CA2586621A1 (enExample)
DE (1) DE602005025911D1 (enExample)
ES (1) ES2358745T3 (enExample)
IL (1) IL182898A0 (enExample)
MX (1) MX2007006050A (enExample)
NO (1) NO20073039L (enExample)
RU (1) RU2007118385A (enExample)
WO (1) WO2006054904A2 (enExample)
ZA (1) ZA200705043B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
US20100233082A1 (en) * 2006-08-28 2010-09-16 Bengt Langstrom 68GA-Labeled Peptide-Based Radiopharmaceuticals
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
WO2009074628A1 (en) * 2007-12-13 2009-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis
AU2009205950C1 (en) 2008-01-18 2015-08-06 Visen Medical, Inc. Fluorescent imaging agents
WO2009140408A2 (en) 2008-05-13 2009-11-19 University Of Kansas Metal abstraction peptide (map) tag and associated methods
GB0814722D0 (en) * 2008-08-12 2008-09-17 Ge Healthcare Ltd Treatment monitoring
GB0910013D0 (en) * 2009-06-10 2009-07-22 Ge Healthcare Ltd PET imaging of fibogenesis
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
CN102504603B (zh) * 2011-10-20 2014-01-29 中国海洋大学 一种多聚物与生物染色剂的偶合物及其制备方法和用途
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CN105939732A (zh) * 2013-12-03 2016-09-14 通用医疗公司 分子成像探针
CN117623996B (zh) * 2022-08-10 2025-07-22 中国药科大学 一种二价keap1-nrf2抑制剂、制备方法及其医药用途

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6048982A (en) 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
JP3038339B2 (ja) 1988-05-02 2000-05-08 ザイナクシス・テクノロジーズ・インコーポレーテッド バイオ粒子の表面膜に対してバイオアフェクティング物質を結合する化合物
GB8903022D0 (en) 1989-02-10 1989-03-30 Celltech Ltd Chemical compounds
WO1993011120A1 (en) 1991-11-27 1993-06-10 Zynaxis Technologies, Incorporated Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles
KR20000052830A (ko) 1996-10-28 2000-08-25 조오지 디빈센조, 토브 아스 헬지, 에바 요한손 진단/치료제 또는 그와 관련된 개선
ES2257771T3 (es) 1996-10-28 2006-08-01 Amersham Health As Agentes de contraste.
CA2278200A1 (en) * 1997-01-29 1998-07-30 Nycomed Imaging As Polymers
JP4549528B2 (ja) 1997-07-28 2010-09-22 ジーイー・ヘルスケア・リミテッド シアニン色素
US5942637A (en) 1998-03-30 1999-08-24 North Dakota State University Research Foundation Compounds containing tetradecachlorocyclohexasilane dianion
US6852318B1 (en) 1998-05-08 2005-02-08 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
EP1075277B2 (en) * 1998-05-08 2012-10-31 The Regents of the University of California Methods for detecting and inhibiting angiogenesis
JP2000095758A (ja) 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US6230777B1 (en) 1999-02-04 2001-05-15 Midmac Systems, Inc. Filter forming and joining apparatus
AU2001250683B2 (en) * 2000-04-12 2006-06-29 Ge Healthcare As Peptide-based compounds
NO20004795D0 (no) 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
CA2429956A1 (en) * 2000-11-27 2002-07-18 Alan P. Carpenter, Jr. Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
IL159310A0 (en) * 2001-07-10 2004-06-01 Amersham Health As Peptide-based compounds
GB0116815D0 (en) * 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
ATE412420T1 (de) 2002-06-17 2008-11-15 Cartela R & D Ab Verfahren und verwendungszwecke der integrin alpha 10 kette zur diagnose und nachweis von atherosklerotischer plaquebildung in vitro
US7063158B2 (en) 2003-06-16 2006-06-20 Deepwater Technologies, Inc. Bottom tensioned offshore oil well production riser
NO20033115D0 (no) 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0317815D0 (en) * 2003-07-30 2003-09-03 Amersham Health As Imaging agents
WO2005019247A2 (en) 2003-08-15 2005-03-03 Board Of Regents, The University Of Texas System Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
JP2007512321A (ja) * 2003-11-24 2007-05-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US7763234B2 (en) * 2004-03-04 2010-07-27 Ge Healthcare As Pharmaceutical compounds
WO2005123768A1 (en) * 2004-06-16 2005-12-29 Ge Healthcare As Peptide-based compounds
US8361443B2 (en) * 2004-06-16 2013-01-29 Ge Healthcare As Peptide-based compounds

Also Published As

Publication number Publication date
JP2012207027A (ja) 2012-10-25
KR20070091609A (ko) 2007-09-11
US8182790B2 (en) 2012-05-22
AU2005307195A1 (en) 2006-05-26
IL182898A0 (en) 2007-08-19
WO2006054904A2 (en) 2006-05-26
JP5116480B2 (ja) 2013-01-09
BRPI0518328A2 (pt) 2008-11-11
WO2006054904A3 (en) 2007-04-05
JP2008520658A (ja) 2008-06-19
EP1814598A2 (en) 2007-08-08
EP2243496A3 (en) 2012-12-26
CN101107016B (zh) 2011-11-16
EP1814598B1 (en) 2011-01-12
NO20073039L (no) 2007-08-16
DE602005025911D1 (de) 2011-02-24
ES2358745T3 (es) 2011-05-13
EP2243496A2 (en) 2010-10-27
ATE494913T1 (de) 2011-01-15
US20090208412A1 (en) 2009-08-20
MX2007006050A (es) 2007-11-14
RU2007118385A (ru) 2008-12-27
CN101107016A (zh) 2008-01-16
CA2586621A1 (en) 2006-05-26

Similar Documents

Publication Publication Date Title
ZA200705043B (en) Contrast agents to target extracellular matrix
WO1998018497A3 (en) Contrast agents
WO2006079120A3 (en) Fc-fusion constructs binding to phosphatidylserine and their therapeutic use
WO1998018496A3 (en) Contrast agents
IL173032A0 (en) Pyridazine derivatives and their use as therapeutic agents
EP2269610A3 (en) Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
IL173396A0 (en) Piperazine derivatives and their use as therapeutic agents
EP2060272A3 (en) Vitamin-mitomycin conjugates
GB0421639D0 (en) Methods and compositions relating to alzheimer's disease
ATE213590T1 (de) Fgf9 als spezifischer ligand für fgfr3
WO2003049684A3 (en) Pseudo-antibody constructs
DE69628731D1 (de) Gelierte magnetisch markierte molekularsysteme als nmr-bilderzeugungsmittel
TW200635612A (en) Use of cyanine dyes for the diagnosis of proliferative diseases
NZ593311A (en) Albumin binding peptide-mediated disease targeting
BRPI0515175A (pt) método para radiofluoração, composto, composição radiofarmacêutica, uso de um conjugado radiorrotulado ou um sal do mesmo, método para diagnose ou formação de imagem in vivo de uma doença ou condição associada com a angiogênese, e, método para monitorar o efeito do tratamento de um corpo humano ou animal com um medicamento para combater uma condição associada com cáncer
WO1999048536A3 (en) Delivery of long lasting therapeutic agents by forming covalent attachments in vivo
AU8366398A (en) Trifunctional reagent for conjugation to a biomolecule
WO2004013307A3 (en) Compounds for targeting hepatocytes
WO2002087497A3 (en) Therapeutic agent/ligand conjugate compositions, their methods of synthesis and use
ATE425770T1 (de) Kontrastmittel
WO2011008985A3 (en) Conjugates comprising dna-binding agent for targeted delivery of therapeutic agents
WO2004110255A3 (en) Antineoplastic agents targeted via glut transporters
AU2003283228A8 (en) Shiga toxin b-subunit as a vector for tumor diagnosis and drug delivery to gb3 expressing tumors
WO2010032248A3 (en) Multifunctional albumin conjugates
WO2004087734A3 (en) Stq-peptides