BRPI0511111A - compostos de pirrol como inibidores de cinase de proteìna de erk, sua sìntese e seus intermediários - Google Patents
compostos de pirrol como inibidores de cinase de proteìna de erk, sua sìntese e seus intermediáriosInfo
- Publication number
- BRPI0511111A BRPI0511111A BRPI0511111-0A BRPI0511111A BRPI0511111A BR PI0511111 A BRPI0511111 A BR PI0511111A BR PI0511111 A BRPI0511111 A BR PI0511111A BR PI0511111 A BRPI0511111 A BR PI0511111A
- Authority
- BR
- Brazil
- Prior art keywords
- protein kinase
- synthesis
- kinase inhibitors
- compounds
- intermediates
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
COMPOSTOS DE PIRROL COMO INIBIDORES DE CINASE DE PROTEìNA DE ERK, SUA SìNTESE E SEUS INTERMEDIáRIOS. A presente invenção refere-se a compostos úteis de inibidores de proteína quinase. A invenção também provê composições farmaceuticamente aceitáveis compreendendo os ditos compostos e métodos de uso das composições no tratamento de vários distúrbios, condições ou distúrbios.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57130904P | 2004-05-14 | 2004-05-14 | |
PCT/US2005/016902 WO2005113541A1 (en) | 2004-05-14 | 2005-05-13 | Pyrrole compounds as inhibitors of erk protein kinase, synthesis thereof and intermediates thereto |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0511111A true BRPI0511111A (pt) | 2007-11-27 |
Family
ID=35106760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0511111-0A BRPI0511111A (pt) | 2004-05-14 | 2005-05-13 | compostos de pirrol como inibidores de cinase de proteìna de erk, sua sìntese e seus intermediários |
Country Status (26)
Country | Link |
---|---|
US (6) | US7354939B2 (pt) |
EP (5) | EP1753738B1 (pt) |
JP (1) | JP5132305B2 (pt) |
CN (1) | CN1976919A (pt) |
AR (2) | AR051735A1 (pt) |
AU (1) | AU2005245885B2 (pt) |
BR (1) | BRPI0511111A (pt) |
CA (1) | CA2566461C (pt) |
CY (1) | CY1122336T1 (pt) |
DK (1) | DK3305776T3 (pt) |
ES (4) | ES2513965T3 (pt) |
HK (2) | HK1203505A1 (pt) |
HU (1) | HUE047130T2 (pt) |
IL (1) | IL179207A0 (pt) |
LT (1) | LT3305776T (pt) |
MX (1) | MXPA06013209A (pt) |
NO (1) | NO20065727L (pt) |
NZ (1) | NZ551582A (pt) |
PL (1) | PL3305776T3 (pt) |
PT (1) | PT3305776T (pt) |
RU (1) | RU2376299C2 (pt) |
SI (1) | SI3305776T1 (pt) |
TW (1) | TW200607803A (pt) |
UA (1) | UA84930C2 (pt) |
WO (1) | WO2005113541A1 (pt) |
ZA (1) | ZA200609975B (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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JP4808154B2 (ja) * | 2003-03-13 | 2011-11-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼインヒビターとして有用な組成物 |
WO2005100342A1 (en) * | 2004-03-26 | 2005-10-27 | Vertex Pharmaceuticals, Incorporated | Pyridine inhibitors of erk2 and uses thereof |
EP1753738B1 (en) * | 2004-05-14 | 2014-07-09 | Vertex Pharmaceuticals Inc. | Pyrrole compounds as inhibitors of ERK protein kinases and pharmaceutical compositions containing these compounds |
US8546404B2 (en) | 2005-12-13 | 2013-10-01 | Merck Sharp & Dohme | Compounds that are ERK inhibitors |
ES2353437T3 (es) | 2006-02-16 | 2011-03-02 | Schering Corporation | Derivados de pirrolidina como inhibidores de erk. |
BRPI0812450A2 (pt) * | 2007-06-05 | 2019-09-24 | Schering Corp | derivados de indazol policíclicos e seu uso como inibidores de erk para o tratamento de câncer |
NZ587504A (en) | 2008-02-21 | 2012-09-28 | Merck Sharp & Dohme | Benzopyrazole derivatives as ERK inhibitors |
CN102146074B (zh) * | 2011-01-26 | 2013-02-06 | 江苏先声药物研究有限公司 | 吡咯衍生物的制备方法及应用 |
WO2012172093A1 (en) | 2011-06-17 | 2012-12-20 | Merz Pharma Gmbh & Co. Kgaa | Dihydroindolizine derivate as metabotropic glutamate receptor modulators |
WO2015057736A1 (en) | 2013-10-14 | 2015-04-23 | Indiana University Research And Technology Corporation | Use of acamprosate to modulate erk 1-2 activation in animal models for fxs and asd and individuals diagnosed with fxs and asd |
US20160264536A1 (en) | 2013-10-23 | 2016-09-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
WO2015095835A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Methods of modulating radioiodine uptake for the treatment of radioiodine-refractory cancers |
WO2015095831A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of mtor and erk inhibitors |
JP6678584B2 (ja) * | 2013-12-20 | 2020-04-22 | バイオメッド バレー ディスカバリーズ,インコーポレイティド | Cdk阻害剤およびerk阻害剤の組み合わせを使用するがん処置 |
WO2015095825A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of type 2 mek and erk inhibitors |
WO2015095833A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Treatment of hematologic cancers |
WO2015095807A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of egfr and erk inhibitors |
EP3082800B1 (en) * | 2013-12-20 | 2022-02-02 | Biomed Valley Discoveries, Inc. | Cancer treatment using combinations of erk and raf inhibitors |
WO2015095842A2 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Methods and compositions for treating non-erk mapk pathway inhibitor-resistant cancers |
EP3082957B1 (en) * | 2013-12-20 | 2022-04-06 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of pi3k/akt pathway and erk inhibitors |
WO2015095838A2 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of mek type i and erk inhibitors |
CN116854662A (zh) * | 2015-01-30 | 2023-10-10 | 生物医学谷探索股份有限公司 | C21H22Cl2N4O2的晶型 |
WO2016123581A1 (en) * | 2015-01-30 | 2016-08-04 | Biomed Valley Discoveries, Inc. | Crystalline c21h22c12n4o2 malonate |
WO2016187028A1 (en) * | 2015-05-15 | 2016-11-24 | Celgene Avilomics Research, Inc. | Heteroaryl compounds, synthesis thereof, and intermediates thereto |
AU2015396809B2 (en) * | 2015-06-03 | 2019-07-11 | Js Innopharm (Shanghai) Ltd. | Heterocyclic compounds for treating psoriasis |
WO2016192063A1 (en) * | 2015-06-03 | 2016-12-08 | Changzhou Jiekai Pharmatech Co. Ltd | Heterocyclic compounds as erk inhibitors |
IL291017B2 (en) | 2015-10-21 | 2023-11-01 | Otsuka Pharma Co Ltd | Benzolactam compounds as protein kinase inhibitors |
EP3170822A1 (en) | 2015-11-18 | 2017-05-24 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
CN109890827A (zh) | 2016-10-05 | 2019-06-14 | 芝诺罗耶尔蒂里程碑有限责任公司 | 螺环化合物 |
GB201706327D0 (en) | 2017-04-20 | 2017-06-07 | Otsuka Pharma Co Ltd | A pharmaceutical compound |
WO2019073435A1 (en) * | 2017-10-12 | 2019-04-18 | Novartis Ag | COMBINATIONS OF MDM2 INHIBITORS WITH ERK INHIBITORS TO TREAT CANCERS |
WO2019180141A1 (en) | 2018-03-23 | 2019-09-26 | Bayer Aktiengesellschaft | Combinations of rogaratinib |
WO2021020841A1 (en) * | 2019-07-29 | 2021-02-04 | Standigm Inc. | Composition for preventing or treating metabolic liver disease |
EP4212531A1 (en) | 2022-01-14 | 2023-07-19 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
WO2023169480A1 (zh) * | 2022-03-08 | 2023-09-14 | 甘李药业股份有限公司 | 氘代化合物,及其制备方法和应用 |
TW202400572A (zh) * | 2022-03-24 | 2024-01-01 | 美商生物醫學谷探索公司 | Erk的吡咯抑制劑之氘化類似物、其合成及其中間物 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
US5565413A (en) * | 1994-12-06 | 1996-10-15 | Zeneca Limited | Substituted pyridyl phenyl ketone herbicides |
US5472966A (en) * | 1995-03-29 | 1995-12-05 | Bristol-Myers Squibb Company | Antidepressant heteroarylaminoalkyl derivatives of naphthyl-monazines |
US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
CA2383492A1 (en) | 1999-06-22 | 2000-12-28 | Takeda Chemical Industries, Ltd. | Acylhydrazine derivatives, their production and use |
MY130778A (en) * | 2001-02-09 | 2007-07-31 | Vertex Pharma | Heterocyclic inhibitiors of erk2 and uses thereof |
EP1506189A1 (en) * | 2002-04-26 | 2005-02-16 | Vertex Pharmaceuticals Incorporated | Pyrrole derivatives as inhibitors of erk2 and uses thereof |
US7361665B2 (en) * | 2002-07-09 | 2008-04-22 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases |
EP1546121B1 (en) * | 2002-07-18 | 2012-08-29 | Janssen Pharmaceutica NV | Substituted triazine kinase inhibitors |
GB0217780D0 (en) * | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Compounds |
BR0313397A (pt) * | 2002-08-14 | 2005-06-28 | Vertex Pharmaceuticals Incorpo | Inibidores de proteina cinase e usos destes |
JP4808154B2 (ja) | 2003-03-13 | 2011-11-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼインヒビターとして有用な組成物 |
EP1753738B1 (en) * | 2004-05-14 | 2014-07-09 | Vertex Pharmaceuticals Inc. | Pyrrole compounds as inhibitors of ERK protein kinases and pharmaceutical compositions containing these compounds |
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2005
- 2005-05-13 EP EP05748073.3A patent/EP1753738B1/en active Active
- 2005-05-13 NZ NZ551582A patent/NZ551582A/en unknown
- 2005-05-13 SI SI200532267T patent/SI3305776T1/sl unknown
- 2005-05-13 WO PCT/US2005/016902 patent/WO2005113541A1/en active Application Filing
- 2005-05-13 EP EP19199330.2A patent/EP3608315B1/en active Active
- 2005-05-13 PL PL17184079T patent/PL3305776T3/pl unknown
- 2005-05-13 ES ES05748073.3T patent/ES2513965T3/es active Active
- 2005-05-13 BR BRPI0511111-0A patent/BRPI0511111A/pt not_active IP Right Cessation
- 2005-05-13 ZA ZA200609975A patent/ZA200609975B/en unknown
- 2005-05-13 ES ES19199330T patent/ES2897422T3/es active Active
- 2005-05-13 AU AU2005245885A patent/AU2005245885B2/en active Active
- 2005-05-13 ES ES17184079T patent/ES2751761T3/es active Active
- 2005-05-13 US US11/128,870 patent/US7354939B2/en not_active Ceased
- 2005-05-13 CA CA2566461A patent/CA2566461C/en active Active
- 2005-05-13 LT LTEP17184079.6T patent/LT3305776T/lt unknown
- 2005-05-13 MX MXPA06013209A patent/MXPA06013209A/es active IP Right Grant
- 2005-05-13 AR ARP050101987A patent/AR051735A1/es not_active Application Discontinuation
- 2005-05-13 JP JP2007513432A patent/JP5132305B2/ja active Active
- 2005-05-13 EP EP17184079.6A patent/EP3305776B1/en active Active
- 2005-05-13 HU HUE17184079A patent/HUE047130T2/hu unknown
- 2005-05-13 RU RU2006144445/04A patent/RU2376299C2/ru active
- 2005-05-13 EP EP21190432.1A patent/EP3943489A1/en active Pending
- 2005-05-13 CN CNA200580021418XA patent/CN1976919A/zh active Pending
- 2005-05-13 UA UAA200613208A patent/UA84930C2/ru unknown
- 2005-05-13 EP EP14163944.3A patent/EP2799434B1/en active Active
- 2005-05-13 TW TW094115644A patent/TW200607803A/zh unknown
- 2005-05-13 PT PT171840796T patent/PT3305776T/pt unknown
- 2005-05-13 DK DK17184079T patent/DK3305776T3/da active
- 2005-05-13 ES ES14163944.3T patent/ES2651439T3/es active Active
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2006
- 2006-11-13 IL IL179207A patent/IL179207A0/en unknown
- 2006-12-12 NO NO20065727A patent/NO20065727L/no not_active Application Discontinuation
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2013
- 2013-08-23 US US14/544,396 patent/USRE46097E1/en active Active
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2015
- 2015-05-04 HK HK15104226.1A patent/HK1203505A1/xx unknown
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2016
- 2016-06-28 US US15/195,021 patent/USRE47318E1/en active Active
- 2016-11-18 AR ARP160103545A patent/AR106755A2/es active IP Right Grant
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2018
- 2018-05-15 HK HK18106295.9A patent/HK1247910A1/zh unknown
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2019
- 2019-03-25 US US16/363,905 patent/USRE48266E1/en active Active
- 2019-12-03 CY CY20191101265T patent/CY1122336T1/el unknown
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2020
- 2020-10-15 US US17/071,566 patent/USRE49500E1/en active Active
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2023
- 2023-02-22 US US18/173,004 patent/US20230183276A1/en active Pending
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Legal Events
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 7A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |