BRPI0418226A - preparação de cloridrato r-5-(2-(2-(2-etoxifenoxietilamino) propil-2-metoxibenzenossulfonamida de alta pureza quìmica - Google Patents

preparação de cloridrato r-5-(2-(2-(2-etoxifenoxietilamino) propil-2-metoxibenzenossulfonamida de alta pureza quìmica

Info

Publication number
BRPI0418226A
BRPI0418226A BRPI0418226-0A BRPI0418226A BRPI0418226A BR PI0418226 A BRPI0418226 A BR PI0418226A BR PI0418226 A BRPI0418226 A BR PI0418226A BR PI0418226 A BRPI0418226 A BR PI0418226A
Authority
BR
Brazil
Prior art keywords
preparation
ethoxyphenoxyethylamino
propyl
high purity
methoxybenzenesulfonamide hydrochloride
Prior art date
Application number
BRPI0418226-0A
Other languages
English (en)
Inventor
Borut Furlan
Anton Copar
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Publication of BRPI0418226A publication Critical patent/BRPI0418226A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C07C303/44—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"PREPARAçãO DE CLORIDRATO R-5-(2-(2-(2ETOXIFENOXIETILAMINO) PROPIL-2-METOXIBENZENOSSULFONAMIDA DE ALTA PUREZA QUìMICA". Na presente invenção, estão descitos o processo para a preparação de cloridrato de tamsulosin e subseqüente purificação com cristalização térmica para proporcionar cloridrato de tamsulosin essencialmente puro.
BRPI0418226-0A 2003-12-29 2004-12-27 preparação de cloridrato r-5-(2-(2-(2-etoxifenoxietilamino) propil-2-metoxibenzenossulfonamida de alta pureza quìmica BRPI0418226A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200300319A SI21656A (sl) 2003-12-29 2003-12-29 Priprava (R)-5-(2-(2-(2-etoksifenoksi) etilamino)-1-propil)-2-metoksibenzensulfonamida hidroklorida z visoko kemijsko čistoto
PCT/SI2004/000047 WO2005063702A1 (en) 2003-12-29 2004-12-27 Preparation of r-5-(2-(2-ethoxyphenoxyetylamino)propyl)-2- methoxybenzenesulphonamide hydrochloride of high chemical

Publications (1)

Publication Number Publication Date
BRPI0418226A true BRPI0418226A (pt) 2007-04-27

Family

ID=34738129

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418226-0A BRPI0418226A (pt) 2003-12-29 2004-12-27 preparação de cloridrato r-5-(2-(2-(2-etoxifenoxietilamino) propil-2-metoxibenzenossulfonamida de alta pureza quìmica

Country Status (11)

Country Link
US (1) US20080033207A1 (pt)
EP (1) EP1708990A1 (pt)
JP (1) JP5305593B2 (pt)
CN (1) CN100584826C (pt)
AU (1) AU2004309315B8 (pt)
BR (1) BRPI0418226A (pt)
CA (1) CA2548316A1 (pt)
RU (1) RU2456269C2 (pt)
SI (1) SI21656A (pt)
WO (1) WO2005063702A1 (pt)
ZA (1) ZA200604240B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057290A1 (es) * 2005-05-04 2007-11-28 Medichem Sa Proceso para la preparacion de tamsulosina
US8273918B2 (en) * 2005-09-12 2012-09-25 Avrobindo Pharma Ltd. Process for preparing tamsulosin hydrochloride
CN101284807B (zh) * 2008-06-11 2010-12-08 药源药物化学（上海）有限公司 盐酸坦索罗辛的制备方法
EP2255793A1 (en) 2009-05-28 2010-12-01 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical composition comprising tamsulosin
CN104926699B (zh) * 2015-07-02 2018-09-25 成都丽凯手性技术有限公司 一种高光学纯度盐酸坦索罗辛的制备方法
EP3359351B1 (de) 2015-10-05 2021-08-25 Martin Zimmer Greifvorrichtung mit integriertem regler
CN112142627A (zh) * 2019-12-31 2020-12-29 北京鑫开元医药科技有限公司 一种盐酸坦索罗辛晶型的制备方法
CN111413435B (zh) * 2020-04-26 2022-07-08 珠海润都制药股份有限公司 一种盐酸坦索罗辛中间体的检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391825A (en) * 1980-02-08 1995-02-21 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine intermediates
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
JPS62114952A (ja) * 1985-11-13 1987-05-26 Yamanouchi Pharmaceut Co Ltd 置換フエネチルアミン誘導体の製造法
JPH02295967A (ja) * 1989-05-10 1990-12-06 Hokuriku Seiyaku Co Ltd フェノキシエチルアミン誘導体の製造方法
JP3662761B2 (ja) * 1999-02-10 2005-06-22 アステラス製薬株式会社 フェノキシアルキルハライド誘導体の新規製造法
KR100525493B1 (ko) * 2001-02-23 2005-11-02 연성정밀화학(주) 설파모일 치환 페네틸아민 유도체의 제조 방법
RU2205001C2 (ru) * 2001-06-05 2003-05-27 Новосибирский научно-исследовательский институт туберкулеза Способ определения вида лечения больных с доброкачественной гиперплазией предстательной железы
CZ20013848A3 (cs) * 2001-10-25 2003-05-14 Léčiva, A.S. Způsob výroby (R)-(-)-5-[2-[2-(2-ethoxyfenoxy)ethylamino]propyl]-2-methoxybenzensulfonamidu
US6835853B2 (en) * 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith

Also Published As

Publication number Publication date
CN1902166A (zh) 2007-01-24
RU2456269C2 (ru) 2012-07-20
SI21656A (sl) 2005-06-30
CA2548316A1 (en) 2005-07-14
ZA200604240B (en) 2007-10-31
JP2007517797A (ja) 2007-07-05
EP1708990A1 (en) 2006-10-11
RU2006127297A (ru) 2008-02-10
CN100584826C (zh) 2010-01-27
AU2004309315B2 (en) 2011-10-20
AU2004309315B8 (en) 2011-12-15
WO2005063702A1 (en) 2005-07-14
JP5305593B2 (ja) 2013-10-02
AU2004309315A1 (en) 2005-07-14
US20080033207A1 (en) 2008-02-07

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.