BRPI0414573A - 7-amino alquilidenil-quinolonas e naftiridonas heterocìclicas - Google Patents
7-amino alquilidenil-quinolonas e naftiridonas heterocìclicasInfo
- Publication number
- BRPI0414573A BRPI0414573A BRPI0414573-9A BRPI0414573A BRPI0414573A BR PI0414573 A BRPI0414573 A BR PI0414573A BR PI0414573 A BRPI0414573 A BR PI0414573A BR PI0414573 A BRPI0414573 A BR PI0414573A
- Authority
- BR
- Brazil
- Prior art keywords
- quinolones
- alkylidenyl
- naphthyridones
- amino heterocyclic
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
"7-AMINO ALQUILIDENIL-QUINOLONAS E NAFTIRIDONAS HETEROCìCLICAS". A presente invenção refere-se a compostos tendo uma estrutura de acordo com a Fórmula I em que n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y a e b são conforme definido acima; ou um isómero ótico, diastereómero ou enantiómero dos mesmos; um sal, hidrato, ou pró-fármaco farmaceuticamente aceitável dos mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50492403P | 2003-09-22 | 2003-09-22 | |
PCT/US2004/029523 WO2005033108A1 (en) | 2003-09-22 | 2004-09-09 | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0414573A true BRPI0414573A (pt) | 2006-11-07 |
Family
ID=34421521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0414573-9A BRPI0414573A (pt) | 2003-09-22 | 2004-09-09 | 7-amino alquilidenil-quinolonas e naftiridonas heterocìclicas |
Country Status (24)
Country | Link |
---|---|
US (1) | US7179805B2 (pt) |
EP (1) | EP1675852B1 (pt) |
JP (2) | JP2007522093A (pt) |
KR (1) | KR101137311B1 (pt) |
CN (1) | CN1997642B (pt) |
AR (1) | AR045805A1 (pt) |
AT (1) | ATE423117T1 (pt) |
AU (1) | AU2004278320B2 (pt) |
BR (1) | BRPI0414573A (pt) |
CA (1) | CA2539349C (pt) |
CY (1) | CY1109424T1 (pt) |
DE (1) | DE602004019555D1 (pt) |
DK (1) | DK1675852T3 (pt) |
ES (1) | ES2321722T3 (pt) |
IL (1) | IL174397A (pt) |
MY (1) | MY176860A (pt) |
NZ (1) | NZ545970A (pt) |
PL (1) | PL1675852T3 (pt) |
PT (1) | PT1675852E (pt) |
RU (1) | RU2350615C2 (pt) |
SI (1) | SI1675852T1 (pt) |
TW (1) | TWI359150B (pt) |
WO (1) | WO2005033108A1 (pt) |
ZA (1) | ZA200603223B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004206998B2 (en) * | 2003-01-24 | 2009-12-17 | The General Hospital Corporation | System and method for identifying tissue using low-coherence interferometry |
US7732612B2 (en) * | 2004-09-09 | 2010-06-08 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
AU2012244358B2 (en) * | 2005-03-21 | 2015-05-28 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
EP2159225A1 (en) * | 2005-06-15 | 2010-03-03 | Hetero Drugs Limited | Gemifloxacin process and polymorphs |
JO2752B1 (en) * | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
WO2007019344A1 (en) | 2005-08-04 | 2007-02-15 | Sirtris Pharmaceuticals, Inc. | Imidazo [2,1-b] thiayole derivatives as sirtuin modulating compounds |
US20100152230A1 (en) * | 2005-09-02 | 2010-06-17 | Pfizer Inc. | Hydroxy substituted 1h-imidazopyridines and methods |
CA2626641A1 (en) * | 2005-10-21 | 2007-07-19 | Glaxo Group Limited | Compounds |
US20070185153A1 (en) | 2005-12-22 | 2007-08-09 | Nathalie Cailleau | Compounds |
JP5097967B2 (ja) * | 2006-03-28 | 2012-12-12 | タイゲン バイオテクノロジー カンパニー,リミテッド | リンゴ酸塩類、及び(3s,5s)−7−[3−アミノ−5−メチルーピペリジニル]−1−シクロプロピル−1,4−ジヒドロ−8−メトキシ−4−オキソ−3−キノリンカルボン酸の多形体類 |
KR20110082635A (ko) | 2006-03-28 | 2011-07-19 | 워너 칠콧 컴퍼니 엘엘씨 | 퀴놀론 중간체를 제조하기 위한 커플링 방법 |
US7528264B2 (en) | 2006-03-28 | 2009-05-05 | The Procter & Gamble Company | Hydride reduction process for preparing quinolone intermediates |
US20080009628A1 (en) * | 2006-07-05 | 2008-01-10 | Michael Reuman | One-Pot Condensation-Reduction Methods for Preparing Substituted Allylic Alcohols |
WO2009046383A1 (en) * | 2007-10-05 | 2009-04-09 | Cylene Pharmaceuticals, Inc. | Quinolone analogs and methods related thereto |
KR20120025519A (ko) | 2009-05-15 | 2012-03-15 | 레드엑스 파마 리미티드 | 산화환원 약물 유도체 |
US20110172193A1 (en) * | 2010-01-11 | 2011-07-14 | Mark Macielag | Pro-drugs of (e)-7-(3-(2-amino-1-fluoroethylidene)piperidin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
CN104098588B (zh) * | 2013-04-02 | 2016-05-25 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一类三环喹诺酮衍生物及其制备方法和用途 |
WO2015179547A2 (en) * | 2014-05-21 | 2015-11-26 | New York University | Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression |
CN108601789A (zh) | 2015-11-20 | 2018-09-28 | 生华生物科技股份有限公司 | 用于治疗癌症的四环喹诺酮类似物组合疗法 |
US9957282B2 (en) | 2015-12-14 | 2018-05-01 | Senhwa Biosciences, Inc. | Crystalline forms of quinolone analogs and their salts |
WO2019168688A2 (en) | 2018-02-15 | 2019-09-06 | Senhwa Biosciences, Inc. | Quinolone analogs and their salts, compositions, and method for their use |
RU2671573C1 (ru) * | 2018-09-03 | 2018-11-02 | Алина Викторовна Шумадалова | 2-[6-метил-4-(тиетан-3-илокси)пиримидин-2-илтио]ацетогидразид малеиновой кислоты, проявляющий противомикробную активность |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS605539B2 (ja) * | 1980-03-17 | 1985-02-12 | 日東紡績株式会社 | 耐アルカリ性、耐熱性無機質繊維 |
FI871419A (fi) | 1986-03-31 | 1987-10-01 | Sankyo Co | Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning. |
JPH0262875A (ja) * | 1988-05-23 | 1990-03-02 | Wakunaga Pharmaceut Co Ltd | 新規イソインドリン誘導体 |
CA1332605C (en) * | 1988-10-03 | 1994-10-18 | Yasuhiro Nishitani | Pyridonecarboxylic acids |
US5580872A (en) * | 1990-05-02 | 1996-12-03 | Abbott Laboratories | Quinolizinone type compounds |
FR2692577B1 (fr) * | 1992-05-26 | 1996-02-02 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
JPH06263754A (ja) * | 1993-03-12 | 1994-09-20 | Hokuriku Seiyaku Co Ltd | 7−アミノピロリジニルキノリン−3−カルボン酸誘導体 |
DE69430581D1 (de) * | 1993-10-14 | 2002-06-13 | Abbott Lab | Verbindungen des chinolizinon-typs |
US5392154A (en) * | 1994-03-30 | 1995-02-21 | Bell Communications Research, Inc. | Self-regulating multiwavelength optical amplifier module for scalable lightwave communications systems |
IL122296A0 (en) * | 1995-06-06 | 1998-04-05 | Abbott Lab | Quinolizinone type compounds |
TR200001435T2 (tr) * | 1997-09-15 | 2000-08-21 | The Procter & Gamble Company | Antimikrobiyal kuinolonlar, bunların bileşimleri ve kullanımları |
KR100330409B1 (ko) * | 1998-07-23 | 2002-08-27 | 한국과학기술원 | 파장분할다중 방식 다중화/역다중화 장치와 이를 이용한 파장분할다중 방식 수동형 광 가입자망 |
US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
-
2004
- 2004-09-09 RU RU2006109004/04A patent/RU2350615C2/ru active
- 2004-09-09 PT PT04783671T patent/PT1675852E/pt unknown
- 2004-09-09 SI SI200431076T patent/SI1675852T1/sl unknown
- 2004-09-09 BR BRPI0414573-9A patent/BRPI0414573A/pt not_active Application Discontinuation
- 2004-09-09 PL PL04783671T patent/PL1675852T3/pl unknown
- 2004-09-09 NZ NZ545970A patent/NZ545970A/en unknown
- 2004-09-09 CN CN2004800337880A patent/CN1997642B/zh not_active Expired - Fee Related
- 2004-09-09 AU AU2004278320A patent/AU2004278320B2/en not_active Ceased
- 2004-09-09 ES ES04783671T patent/ES2321722T3/es active Active
- 2004-09-09 WO PCT/US2004/029523 patent/WO2005033108A1/en active Application Filing
- 2004-09-09 US US10/937,238 patent/US7179805B2/en active Active
- 2004-09-09 KR KR1020067007817A patent/KR101137311B1/ko active IP Right Grant
- 2004-09-09 DK DK04783671T patent/DK1675852T3/da active
- 2004-09-09 EP EP04783671A patent/EP1675852B1/en active Active
- 2004-09-09 DE DE602004019555T patent/DE602004019555D1/de active Active
- 2004-09-09 CA CA2539349A patent/CA2539349C/en not_active Expired - Fee Related
- 2004-09-09 AT AT04783671T patent/ATE423117T1/de active
- 2004-09-09 JP JP2006526944A patent/JP2007522093A/ja active Pending
- 2004-09-21 TW TW093128488A patent/TWI359150B/zh not_active IP Right Cessation
- 2004-09-21 MY MYPI20043865A patent/MY176860A/en unknown
- 2004-09-22 AR ARP040103422A patent/AR045805A1/es not_active Application Discontinuation
-
2006
- 2006-03-19 IL IL174397A patent/IL174397A/en active IP Right Grant
- 2006-04-21 ZA ZA2006/03223A patent/ZA200603223B/en unknown
-
2009
- 2009-04-29 CY CY20091100474T patent/CY1109424T1/el unknown
-
2012
- 2012-03-07 JP JP2012050624A patent/JP5431515B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0414573A (pt) | 7-amino alquilidenil-quinolonas e naftiridonas heterocìclicas | |
BRPI0609426B8 (pt) | naftiridonas e quinolonas de alquilidenil-heterocíclicas de 7-amino | |
BRPI0412347A (pt) | 2-aminofenil-4-fenilpiridinas como inibidores de quinase | |
CY1118723T1 (el) | Ενωσεις βενζοθειαζολιου και αζαβενζοθειαζολιου χρησιμες ως αναστολεiς κινασης | |
BR0312934A (pt) | Derivados de 8-hidróxi quinolina | |
ATE556058T1 (de) | 1-(2h)-isochinolonderivat | |
PE20081530A1 (es) | Nuevos compuestos 617 | |
NO20060665L (no) | N-substituerte pyrazolyl-amidyl-benzimidazolyl C-kit inhibitorer | |
ATE241621T1 (de) | Arylsulfonyle als faktor xa inhibitoren | |
CY1106679T1 (el) | Αζαδικυκλικες ετεροκυκλικες ενωσεις ως τροποποιητες κανναβινοειδους υποδοχεα | |
NO20021358D0 (no) | Alkylendiamin-substituerte heterocykler | |
EA200500017A1 (ru) | Новые соединения | |
WO2004013120A8 (en) | Novel benzodioxoles | |
JO2282B1 (en) | Oxazole derivatives | |
MXPA05013474A (es) | Derivados de quinolilamida como antagonistas de ccr-5. | |
ATE374190T1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
TW200510317A (en) | Caspase inhibitors and uses thereof | |
ATE449776T1 (de) | Pyrroloä2,3-cüpyridinderivate | |
EA200970372A1 (ru) | Ингибитор развития болезни альцгеймера, содержащий гетероциклическое соединение | |
EA200401455A1 (ru) | Производные бензоксазина в качестве модуляторов 5-htи их применение | |
ATE498600T1 (de) | Inden derivate als pharmazeutika | |
MY138466A (en) | Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders | |
MXPA05009523A (es) | Derivados de quinolina/benzoxazinona y sus usos. | |
DE602004005881D1 (de) | Substituierte pyrazinonverbindungen zur behandlung von entzündungen | |
MXPA04000036A (es) | Benzofuranos sustituidos con (hetero) arilo como ligandos 5-ht. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C07D 471/04 (2006.01), C07D 401/04 (2006.01), C07D |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |