DK1675852T3 - Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner - Google Patents

Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner

Info

Publication number
DK1675852T3
DK1675852T3 DK04783671T DK04783671T DK1675852T3 DK 1675852 T3 DK1675852 T3 DK 1675852T3 DK 04783671 T DK04783671 T DK 04783671T DK 04783671 T DK04783671 T DK 04783671T DK 1675852 T3 DK1675852 T3 DK 1675852T3
Authority
DK
Denmark
Prior art keywords
naphthyridones
alkylidenyl
quinolones
heterocyclic
amino
Prior art date
Application number
DK04783671T
Other languages
Danish (da)
English (en)
Inventor
Grant Iii Eugene Bowers
Mark Joseph Macielag
Xiaoqing Xu
Steven David Paget
Michele Ann Weidner-Wells
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1675852T3 publication Critical patent/DK1675852T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK04783671T 2003-09-22 2004-09-09 Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner DK1675852T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50492403P 2003-09-22 2003-09-22
PCT/US2004/029523 WO2005033108A1 (en) 2003-09-22 2004-09-09 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

Publications (1)

Publication Number Publication Date
DK1675852T3 true DK1675852T3 (da) 2009-05-25

Family

ID=34421521

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04783671T DK1675852T3 (da) 2003-09-22 2004-09-09 Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner

Country Status (24)

Country Link
US (1) US7179805B2 (pt)
EP (1) EP1675852B1 (pt)
JP (2) JP2007522093A (pt)
KR (1) KR101137311B1 (pt)
CN (1) CN1997642B (pt)
AR (1) AR045805A1 (pt)
AT (1) ATE423117T1 (pt)
AU (1) AU2004278320B2 (pt)
BR (1) BRPI0414573A (pt)
CA (1) CA2539349C (pt)
CY (1) CY1109424T1 (pt)
DE (1) DE602004019555D1 (pt)
DK (1) DK1675852T3 (pt)
ES (1) ES2321722T3 (pt)
IL (1) IL174397A (pt)
MY (1) MY176860A (pt)
NZ (1) NZ545970A (pt)
PL (1) PL1675852T3 (pt)
PT (1) PT1675852E (pt)
RU (1) RU2350615C2 (pt)
SI (1) SI1675852T1 (pt)
TW (1) TWI359150B (pt)
WO (1) WO2005033108A1 (pt)
ZA (1) ZA200603223B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004206998B2 (en) * 2003-01-24 2009-12-17 The General Hospital Corporation System and method for identifying tissue using low-coherence interferometry
US7732612B2 (en) * 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
US20090156577A1 (en) * 2004-09-09 2009-06-18 Benjamin Davis 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
AU2012244358B2 (en) * 2005-03-21 2015-05-28 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
EP2159225A1 (en) * 2005-06-15 2010-03-03 Hetero Drugs Limited Gemifloxacin process and polymorphs
JO2752B1 (en) * 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
WO2007019344A1 (en) 2005-08-04 2007-02-15 Sirtris Pharmaceuticals, Inc. Imidazo [2,1-b] thiayole derivatives as sirtuin modulating compounds
US20100152230A1 (en) * 2005-09-02 2010-06-17 Pfizer Inc. Hydroxy substituted 1h-imidazopyridines and methods
CA2626641A1 (en) * 2005-10-21 2007-07-19 Glaxo Group Limited Compounds
US20070185153A1 (en) 2005-12-22 2007-08-09 Nathalie Cailleau Compounds
JP5097967B2 (ja) * 2006-03-28 2012-12-12 タイゲン バイオテクノロジー カンパニー,リミテッド リンゴ酸塩類、及び(3s,5s)−7−[3−アミノ−5−メチルーピペリジニル]−1−シクロプロピル−1,4−ジヒドロ−8−メトキシ−4−オキソ−3−キノリンカルボン酸の多形体類
KR20110082635A (ko) 2006-03-28 2011-07-19 워너 칠콧 컴퍼니 엘엘씨 퀴놀론 중간체를 제조하기 위한 커플링 방법
US7528264B2 (en) 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
US20080009628A1 (en) * 2006-07-05 2008-01-10 Michael Reuman One-Pot Condensation-Reduction Methods for Preparing Substituted Allylic Alcohols
WO2009046383A1 (en) * 2007-10-05 2009-04-09 Cylene Pharmaceuticals, Inc. Quinolone analogs and methods related thereto
KR20120025519A (ko) 2009-05-15 2012-03-15 레드엑스 파마 리미티드 산화환원 약물 유도체
US20110172193A1 (en) * 2010-01-11 2011-07-14 Mark Macielag Pro-drugs of (e)-7-(3-(2-amino-1-fluoroethylidene)piperidin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CN104098588B (zh) * 2013-04-02 2016-05-25 广州白云山医药集团股份有限公司白云山制药总厂 一类三环喹诺酮衍生物及其制备方法和用途
WO2015179547A2 (en) * 2014-05-21 2015-11-26 New York University Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression
CN108601789A (zh) 2015-11-20 2018-09-28 生华生物科技股份有限公司 用于治疗癌症的四环喹诺酮类似物组合疗法
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
WO2019168688A2 (en) 2018-02-15 2019-09-06 Senhwa Biosciences, Inc. Quinolone analogs and their salts, compositions, and method for their use
RU2671573C1 (ru) * 2018-09-03 2018-11-02 Алина Викторовна Шумадалова 2-[6-метил-4-(тиетан-3-илокси)пиримидин-2-илтио]ацетогидразид малеиновой кислоты, проявляющий противомикробную активность

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS605539B2 (ja) * 1980-03-17 1985-02-12 日東紡績株式会社 耐アルカリ性、耐熱性無機質繊維
FI871419A (fi) 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5580872A (en) * 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
JPH06263754A (ja) * 1993-03-12 1994-09-20 Hokuriku Seiyaku Co Ltd 7−アミノピロリジニルキノリン−3−カルボン酸誘導体
DE69430581D1 (de) * 1993-10-14 2002-06-13 Abbott Lab Verbindungen des chinolizinon-typs
US5392154A (en) * 1994-03-30 1995-02-21 Bell Communications Research, Inc. Self-regulating multiwavelength optical amplifier module for scalable lightwave communications systems
IL122296A0 (en) * 1995-06-06 1998-04-05 Abbott Lab Quinolizinone type compounds
TR200001435T2 (tr) * 1997-09-15 2000-08-21 The Procter & Gamble Company Antimikrobiyal kuinolonlar, bunların bileşimleri ve kullanımları
KR100330409B1 (ko) * 1998-07-23 2002-08-27 한국과학기술원 파장분할다중 방식 다중화/역다중화 장치와 이를 이용한 파장분할다중 방식 수동형 광 가입자망
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments

Also Published As

Publication number Publication date
ZA200603223B (en) 2007-09-26
PT1675852E (pt) 2009-03-25
TW200526654A (en) 2005-08-16
KR20060097119A (ko) 2006-09-13
IL174397A0 (en) 2006-08-01
NZ545970A (en) 2009-05-31
ATE423117T1 (de) 2009-03-15
JP2007522093A (ja) 2007-08-09
CN1997642B (zh) 2012-06-13
SI1675852T1 (sl) 2009-06-30
BRPI0414573A (pt) 2006-11-07
AR045805A1 (es) 2005-11-16
RU2006109004A (ru) 2007-09-27
US7179805B2 (en) 2007-02-20
EP1675852B1 (en) 2009-02-18
JP5431515B2 (ja) 2014-03-05
RU2350615C2 (ru) 2009-03-27
PL1675852T3 (pl) 2009-07-31
EP1675852A1 (en) 2006-07-05
CY1109424T1 (el) 2014-08-13
DE602004019555D1 (de) 2009-04-02
KR101137311B1 (ko) 2012-04-23
AU2004278320B2 (en) 2010-06-24
TWI359150B (en) 2012-03-01
CN1997642A (zh) 2007-07-11
WO2005033108A1 (en) 2005-04-14
CA2539349A1 (en) 2005-04-14
CA2539349C (en) 2012-06-05
AU2004278320A1 (en) 2005-04-14
MY176860A (en) 2020-08-24
ES2321722T3 (es) 2009-06-10
US20050101588A1 (en) 2005-05-12
IL174397A (en) 2014-01-30
JP2012162529A (ja) 2012-08-30

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