BR9909641A - Processos para tratamento ou para prevenção de asma ou de seus sintomas, de dermatite, de rinite alérgica e de inflamação em um humano e de uma condição responsiva à inibição de leucotrieno, e, composição farmacêutica - Google Patents

Processos para tratamento ou para prevenção de asma ou de seus sintomas, de dermatite, de rinite alérgica e de inflamação em um humano e de uma condição responsiva à inibição de leucotrieno, e, composição farmacêutica

Info

Publication number
BR9909641A
BR9909641A BR9909641-2A BR9909641A BR9909641A BR 9909641 A BR9909641 A BR 9909641A BR 9909641 A BR9909641 A BR 9909641A BR 9909641 A BR9909641 A BR 9909641A
Authority
BR
Brazil
Prior art keywords
inflammation
symptoms
processes
dermatitis
human
Prior art date
Application number
BR9909641-2A
Other languages
English (en)
Inventor
Paul D Rubin
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of BR9909641A publication Critical patent/BR9909641A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSOS PARA TRATAMENTO OU PARA PREVENçãO DE ASMA OU DE SEUS SINTOMAS, DE DERMATITE, DE RINITE ALéRGICA E DE INFLAMAçãO EM UM HUMANO E DE UMA CONDIçãO RESPONSIVA à INIBIçãO DE LEUCOTRIENO, E, COMPOSIçãO FARMACêUTICA" Processos e composições farmacêuticas empregando um metabólito de terfenadina e um inibidor de leucotrieno para o tratamento ou a prevenção de inflamação ou de distúrbios alérgicos, tal como asma, ou seus sintomas. Também estão incluídos processos e composições empregando um metabólito de terfenadina, um inibidor de leucotrieno, e um descongestionante para o tratamento ou a prevenção de inflamação ou de distúrbios alérgicos, tal como asma, ou seus sintomas.
BR9909641-2A 1998-04-14 1999-04-13 Processos para tratamento ou para prevenção de asma ou de seus sintomas, de dermatite, de rinite alérgica e de inflamação em um humano e de uma condição responsiva à inibição de leucotrieno, e, composição farmacêutica BR9909641A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/059,570 US6194431B1 (en) 1998-04-14 1998-04-14 Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
PCT/US1999/008077 WO1999052554A1 (en) 1998-04-14 1999-04-13 Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors

Publications (1)

Publication Number Publication Date
BR9909641A true BR9909641A (pt) 2000-12-19

Family

ID=22023833

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909641-2A BR9909641A (pt) 1998-04-14 1999-04-13 Processos para tratamento ou para prevenção de asma ou de seus sintomas, de dermatite, de rinite alérgica e de inflamação em um humano e de uma condição responsiva à inibição de leucotrieno, e, composição farmacêutica

Country Status (21)

Country Link
US (4) US6194431B1 (pt)
EP (2) EP1071463B1 (pt)
JP (1) JP2002511426A (pt)
KR (1) KR100686297B1 (pt)
CN (2) CN1768749A (pt)
AT (1) ATE328608T1 (pt)
AU (1) AU763979B2 (pt)
BR (1) BR9909641A (pt)
CA (1) CA2328074C (pt)
CY (1) CY1106800T1 (pt)
DE (1) DE69931771T2 (pt)
DK (1) DK1071463T3 (pt)
ES (1) ES2260910T3 (pt)
HU (1) HU228035B1 (pt)
IL (2) IL138993A0 (pt)
NO (1) NO20005147L (pt)
NZ (1) NZ507762A (pt)
PL (1) PL343526A1 (pt)
PT (1) PT1071463E (pt)
WO (1) WO1999052554A1 (pt)
ZA (1) ZA200005553B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194431B1 (en) 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
US20020198246A1 (en) * 1998-09-30 2002-12-26 Ono Pharmaceutical Co., Ltd. Agent for preventing and/or treating sinusitis
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6440994B1 (en) 2000-03-29 2002-08-27 Richard J. Sanders, Jr. Method of treating acne
US20020198228A1 (en) * 2001-04-03 2002-12-26 Kaura Sita R. Composition and method for the treatment of respiratory desease
AU2003237253A1 (en) * 2002-05-29 2003-12-19 Aventis Pharmaceuticals Holdings Inc. Method of treating asthma using fexofenadine
US20040115647A1 (en) * 2002-12-12 2004-06-17 Paterson Thomas S. Apparatus and method for identifying biomarkers using a computer model
WO2009027852A2 (en) * 2007-08-28 2009-03-05 Agi Therapeutics, P.L.C. Methods and compositions for treating gastrointestinal conditions
WO2016011254A1 (en) * 2014-07-16 2016-01-21 Henry J. Legere Md, Pa Combinations of antihistamines and leukotriene antagonists and methods of use thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878217A (en) 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4783465A (en) 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4552899A (en) 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4617407A (en) * 1984-08-30 1986-10-14 Merck Frosst Canada, Inc. Leukotriene antagonists
US4742175A (en) 1986-05-07 1988-05-03 Merrell Dow Pharmaceuticals Inc. Preparation of polymorphically pure terfenadine
US4800162A (en) 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
US4829064A (en) 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4929605A (en) 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
US4996061A (en) 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
CN1053570C (zh) 1987-10-07 2000-06-21 默尔多药物公司 哌啶子基链烷醇的药用组合物-减充血剂复方的制备方法
US5057427A (en) 1988-04-07 1991-10-15 Sepracor, Inc. Method for resolution of stereoisomers
US4990259A (en) 1988-12-16 1991-02-05 The Amalgamated Sugar Company Chromatographic separator sorbent bed preparation
US5019591A (en) 1989-02-17 1991-05-28 Pennsylvania Research Corporation Method for treating retinopathy and other small vessel disorders associated with diabetes
JPH07506828A (ja) 1992-05-11 1995-07-27 メレルダウファーマス−ティカルズ　インコーポレイテッド 肝臓が損われた患者での抗ヒスタミン剤としてのターフェナジン誘導体の用途
JP3041954B2 (ja) 1992-08-03 2000-05-15 セプラコア インコーポレーテッド アレルギー疾患治療用のテルフェナジン代謝物及びその光学的に純粋な異性体
AU670004B2 (en) 1993-06-24 1996-06-27 Albany Molecular Research, Inc. Piperidine derivatives and process for their production
WO1995010278A1 (en) 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
JPH11507670A (ja) * 1995-06-12 1999-07-06 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ−２インヒビターと５−リポキシゲナーゼインヒビターの組合せによる炎症と炎症関連疾患の治療
CA2245162A1 (en) 1996-02-08 1997-08-14 Merck & Co., Inc. Method of treatment and pharmaceutical composition
ES2169351T3 (es) * 1996-02-13 2002-07-01 Searle & Co Combinaciones que tienen efectos inmunosupresores, que contienen inhibidores de ciclooxigenasa-2 y 5-lipoxigenasa.
US5919776A (en) * 1996-12-20 1999-07-06 Merck & Co., Inc. Substituted aminoquinolines as modulators of chemokine receptor activity
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
CA2315721C (en) * 1997-12-23 2008-08-12 Schering Corporation Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors

Also Published As

Publication number Publication date
DE69931771T2 (de) 2006-10-12
CA2328074C (en) 2012-02-21
US20120149730A1 (en) 2012-06-14
ZA200005553B (en) 2001-05-17
US6194431B1 (en) 2001-02-27
NZ507762A (en) 2003-09-26
US8404715B2 (en) 2013-03-26
EP1071463A1 (en) 2001-01-31
PT1071463E (pt) 2006-10-31
ES2260910T3 (es) 2006-11-01
KR20010042655A (ko) 2001-05-25
AU763979B2 (en) 2003-08-07
AU3640999A (en) 1999-11-01
US6509353B1 (en) 2003-01-21
CY1106800T1 (el) 2012-05-23
JP2002511426A (ja) 2002-04-16
HU228035B1 (en) 2012-08-28
IL138993A0 (en) 2001-11-25
HUP0102239A2 (hu) 2002-03-28
HUP0102239A3 (en) 2002-06-28
ATE328608T1 (de) 2006-06-15
CN1768749A (zh) 2006-05-10
NO20005147L (no) 2000-11-07
CN1305385A (zh) 2001-07-25
CA2328074A1 (en) 1999-10-21
DK1071463T3 (da) 2006-09-25
IL138993A (en) 2011-01-31
DE69931771D1 (de) 2006-07-20
US20030083343A1 (en) 2003-05-01
WO1999052554A1 (en) 1999-10-21
KR100686297B1 (ko) 2007-02-23
EP1707216A1 (en) 2006-10-04
PL343526A1 (en) 2001-08-27
NO20005147D0 (no) 2000-10-13
EP1071463B1 (en) 2006-06-07

Similar Documents

Publication Publication Date Title
BR9911666A (pt) Combinação farmacêutica, uso da combinação, processo para tratamento de uma doença inflamatória em uma pessoa sofrendo de ou susceptìvel a tal doença, e, composição farmacêutica
BR9807673A (pt) Processos para tratar asma alérgica e dermatite em um humano e composição farmacêutica.
EP1769797A3 (en) Methods and compositions using cetirizine in combination with leukotriene inhibitors for treating conditions responsive to leukotriene inhibition
CO5160320A1 (es) Metodos y composiciones para la prevencion de tolerancia a medicamentos das.
BR9808948A (pt) Composição de confeitaria
BRPI0414876A (pt) compostos e composições farmcêuticas para prevenção de overdose ou abuso e respectivos usos
BR0109211A (pt) Compostos com atividade 5-ht1a úteis para o tratamento de distúrbios da retina externa
BR9911440A (pt) Composição para a prevenção e/ou tratamento de osteoporose e alterações devido à sìndrome de menopausa
BR0000214A (pt) Loção capilar com propriedades melhoradas em sua ação protetora do cabelo e preventiva de sua queda e de redução dos efeitos externos da alopecia androgenética e com isso da queda do cabelo
BRPI0411319A (pt) compostos terapeuticamente ativos e sua utilização
SE9804000D0 (sv) New composition of matter
BRPI0411295A (pt) compostos e seu uso na terapia
BR9909641A (pt) Processos para tratamento ou para prevenção de asma ou de seus sintomas, de dermatite, de rinite alérgica e de inflamação em um humano e de uma condição responsiva à inibição de leucotrieno, e, composição farmacêutica
BR9912179A (pt) Composição neuroprotetora para a prevenção e/ou tratamento de alterações nervosas e do comportamento devido a estados de ansiedade ou depressão
BR0317361A (pt) Método de tratamento, prevenção ou inibição de um distúrbio do snc e/ou dor e inflamação utilizando uma associação de duloxetina, venlafaxina ou atomoxetina e um inibidor seletivo da ciclooxigenase-2 e suas formulações
BRPI0409199A (pt) composição para a prevenção ou tratamento de doenças alérgicas usando extrato de arroz preto e seu uso terapêutico
DK0909556T3 (da) Rosaceae-ekstrakt som bradykininantagonist
BR9812660A (pt) Composições e métodos para tratar distúrbios respiratórios
BR0012327A (pt) Pirrolidinas e piperidinas neurotróficas, e composições e métodos relacionados
DK0832078T3 (da) N-hydroxyurinstoffer som anti-inflammatoriske midler
BR0005010A (pt) Composição para tratamento de distúrbios de secreção externa exceto a hipolacrimação e seu uso
ITRM990707A0 (it) Composizione per la prevenzione e/o il trattamento di disturbi dovutiad un alterato metabolismo dei lipidi, che comprende propionil l-carni
WO2000021512A3 (en) Composition and method for treating allergic diseases
DK0752990T3 (da) Benzisothiazolderivater som inhibitorer af 5-lipoxygenasebiosyntese
WO1999034763A3 (en) Pharmaceutical compositions comprising thiram for inhibiting angiogenesis

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIDO O PEDIDO COM BASE NOS ARTIGOS 8O, 13 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.